SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bge'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 3bge PREDICTED ATPASE
(Haemophilus
influenzae) 		5 / 11 ARG A 279
ALA A 278
LEU A 261
ALA A 260
LEU A 274
 None
 1.12A 2bxeB-3bgeA:
2.4		 2bxeB-3bgeA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_A_IBPA2001_1
(SERUM ALBUMIN)		 3bge PREDICTED ATPASE
(Haemophilus
influenzae) 		5 / 11 LEU A 295
VAL A 302
GLY A 303
ALA A 309
LEU A 339
 None
 1.27A 2bxgA-3bgeA:
2.4		 2bxgA-3bgeA:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 3bge PREDICTED ATPASE
(Haemophilus
influenzae) 		5 / 12 LEU A 261
ILE A 336
ALA A 335
ALA A 298
GLY A 303
 None
 0.98A 4enhA-3bgeA:
undetectable		 4enhA-3bgeA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 3bge PREDICTED ATPASE
(Haemophilus
influenzae) 		4 / 6 ARG A 420
GLY A 421
ALA A 347
GLU A 423
 None
 1.07A 4g0uA-3bgeA:
undetectable		 4g0uA-3bgeA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3bge PREDICTED ATPASE
(Haemophilus
influenzae) 		4 / 5 ALA A 351
TYR A 414
HIS A 370
PHE A 405
 None
None
None
SO4  A   1 (-4.8A)
 1.21A 4ze2A-3bgeA:
undetectable		 4ze2A-3bgeA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3bge PREDICTED ATPASE
(Haemophilus
influenzae) 		5 / 8 ILE A 426
PRO A 307
ALA A 351
THR A 350
TYR A 349
 None
 1.45A 6cduD-3bgeA:
undetectable
6cduE-3bgeA:
undetectable		 6cduD-3bgeA:
20.06
6cduE-3bgeA:
20.06