SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bgf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I7Z_A_COCA301_1
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 3bgf F26G19 FAB
(Mus
musculus) 		4 / 8 TYR L  86
LEU L  73
LEU L  89
SER L  34
 None
 0.89A 1i7zA-3bgfL:
24.6		 1i7zA-3bgfL:
58.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LBC_A_CYZA330_1
(GLUTAMINE RECEPTOR 2)		 3bgf F26G19 FAB
(Mus
musculus) 		5 / 12 MET L 175
SER L 174
LEU H 179
SER H 180
SER H 182
 None
 1.46A 1lbcA-3bgfL:
undetectable
1lbcC-3bgfL:
undetectable		 1lbcA-3bgfL:
20.22
1lbcC-3bgfL:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_A_SAMA5635_0
(PROTEIN RDMB)		 3bgf F26G19 FAB
F26G19 FAB
(Mus
musculus;
Mus
musculus) 		5 / 12 GLY L 101
GLY L 100
GLY L  99
LEU H  45
SER L   7
 None
 1.13A 1xdsA-3bgfL:
undetectable		 1xdsA-3bgfL:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDS_B_SAMB9635_0
(PROTEIN RDMB)		 3bgf F26G19 FAB
F26G19 FAB
(Mus
musculus;
Mus
musculus) 		5 / 12 GLY L 101
GLY L 100
GLY L  99
LEU H  45
SER L   7
 None
 1.12A 1xdsB-3bgfL:
undetectable		 1xdsB-3bgfL:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_G_BEZG3385_0
(CES1 PROTEIN)		 3bgf F26G19 FAB
(Mus
musculus) 		3 / 3 SER L 177
VAL L 115
LEU L 136
 None
 0.72A 1yajG-3bgfL:
undetectable		 1yajG-3bgfL:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD2_A_CHDA2_0
(FERROCHELATASE)		 3bgf F26G19 FAB
F26G19 FAB
(Mus
musculus;
Mus
musculus) 		4 / 8 MET L 175
LEU L 136
SER H 180
VAL L 159
 None
 0.93A 2qd2A-3bgfL:
undetectable		 2qd2A-3bgfL:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_A_NCAA302_0
(ADP-RIBOSYL CYCLASE
1)		 3bgf F26G19 FAB
F26G19 FAB
(Mus
musculus;
Mus
musculus) 		4 / 7 TRP L  96
LEU L  89
TRP H 103
SER L  34
 None
 1.09A 3dzgA-3bgfL:
undetectable		 3dzgA-3bgfL:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 3bgf F26G19 FAB
F26G19 FAB
(Mus
musculus;
Mus
musculus) 		4 / 7 TRP L  96
LEU L  89
TRP H 103
SER L  34
 None
 1.10A 3dzgB-3bgfL:
undetectable		 3dzgB-3bgfL:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 3bgf F26G19 FAB
F26G19 FAB
(Mus
musculus;
Mus
musculus) 		4 / 7 ILE H  37
LEU H  45
SER L  34
VAL L  58
 None
 0.99A 3r9vA-3bgfH:
undetectable
3r9vB-3bgfH:
undetectable		 3r9vA-3bgfH:
22.90
3r9vB-3bgfH:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 3bgf F26G19 FAB
SPIKE PROTEIN S1
(Mus
musculus;
Severe
acute
respiratory
syndrome-related
coronavirus) 		5 / 12 GLN H  99
GLY S 391
GLY S 490
GLN S 492
ASP S 392
 None
 1.33A 3t7sD-3bgfH:
undetectable		 3t7sD-3bgfH:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB160_0
(HEME-BINDING PROTEIN
HUTZ)		 3bgf F26G19 FAB
(Mus
musculus) 		4 / 4 LEU L  15
GLY L  16
LEU L  78
GLU L  79
 None
 1.03A 3tgvB-3bgfL:
undetectable		 3tgvB-3bgfL:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3bgf SPIKE PROTEIN S1
(Severe
acute
respiratory
syndrome-related
coronavirus) 		5 / 12 PHE S 329
LEU S 374
VAL S 369
PHE S 501
PHE S 364
 None
 1.17A 3u9fB-3bgfS:
undetectable
3u9fC-3bgfS:
undetectable		 3u9fB-3bgfS:
21.89
3u9fC-3bgfS:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_R_CLMR221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3bgf SPIKE PROTEIN S1
(Severe
acute
respiratory
syndrome-related
coronavirus) 		5 / 10 PHE S 329
SER S 353
LEU S 374
VAL S 369
PHE S 501
 None
 1.43A 3u9fR-3bgfS:
undetectable		 3u9fR-3bgfS:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3bgf F26G19 FAB
F26G19 FAB
(Mus
musculus;
Mus
musculus) 		5 / 12 ILE L  48
GLN L   6
TYR L  86
GLN H  39
LEU H  45
 None
 1.46A 4qztA-3bgfL:
undetectable		 4qztA-3bgfL:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_C_RTLC201_0
(RETINOL-BINDING
PROTEIN 2)		 3bgf F26G19 FAB
F26G19 FAB
(Mus
musculus;
Mus
musculus) 		5 / 12 ALA L  25
GLN L  90
THR H 100
ARG L  66
TYR L  32
 None
 1.47A 4qztC-3bgfL:
undetectable		 4qztC-3bgfL:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 3bgf F26G19 FAB
(Mus
musculus) 		5 / 12 GLY H 104
GLN L  37
LEU L  36
GLU L  38
LEU H  45
 None
 1.22A 5nwwA-3bgfH:
undetectable		 5nwwA-3bgfH:
15.38