SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bgk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		5 / 11 LEU A  85
LEU A 124
LEU A  28
VAL A 113
ILE A 118
 None
 1.43A 1ee2B-3bgkA:
6.2		 1ee2B-3bgkA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ESW_A_ACRA652_1
(AMYLOMALTASE)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 6 GLY A 214
ASP A 217
GLY A  37
TYR A  36
 PO4  A 278 (-3.3A)
PO4  A 278 (-3.1A)
None
None
 0.97A 1eswA-3bgkA:
undetectable		 1eswA-3bgkA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 5 VAL A  55
VAL A  27
GLN A 122
PHE A  24
 None
 1.34A 3bjwH-3bgkA:
undetectable		 3bjwH-3bgkA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC59_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		3 / 3 GLY A  25
GLY A  51
GLY A  53
 None
 0.38A 3bogC-3bgkA:
undetectable		 3bogC-3bgkA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		5 / 12 LEU A 101
TYR A  36
ALA A  39
GLY A  37
GLY A  31
 None
 1.25A 3ou7A-3bgkA:
4.5		 3ou7A-3bgkA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		5 / 12 LEU A 101
TYR A  36
ALA A  39
GLY A  37
GLY A  31
 None
 1.25A 3ou7D-3bgkA:
4.5		 3ou7D-3bgkA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		5 / 11 ILE A 184
ILE A 125
ILE A 194
ALA A 220
VAL A 227
 None
 0.96A 3tmzA-3bgkA:
undetectable		 3tmzA-3bgkA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		3 / 3 ASP A 112
ARG A 137
ASP A 105
 None
 0.81A 4fp9A-3bgkA:
4.5		 4fp9A-3bgkA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		5 / 12 GLY A 225
ALA A  52
VAL A  55
LEU A  29
SER A 265
 None
 1.16A 4pd5A-3bgkA:
undetectable		 4pd5A-3bgkA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		5 / 12 GLY A 225
ALA A  52
VAL A  55
LEU A  29
SER A 265
 None
 1.19A 4pd9A-3bgkA:
1.6		 4pd9A-3bgkA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 5 GLY A 214
THR A 218
GLN A 210
THR A 212
 PO4  A 278 (-3.3A)
None
None
None
 1.16A 5h5fA-3bgkA:
3.1		 5h5fA-3bgkA:
25.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA301_1
(CHITOSANASE)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 8 ILE A 268
GLY A 221
THR A 218
LEU A  29
 None
 1.03A 5hwaA-3bgkA:
undetectable		 5hwaA-3bgkA:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 4 GLN A 146
THR A 144
THR A 150
LEU A  96
 None
 1.43A 5m5kA-3bgkA:
6.5		 5m5kA-3bgkA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5K_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 4 GLN A 146
THR A 144
THR A 150
LEU A  96
 None
 1.45A 5m5kC-3bgkA:
6.3		 5m5kC-3bgkA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 4 GLN A 146
THR A 144
THR A 150
LEU A  96
 None
 1.41A 5m66B-3bgkA:
7.2		 5m66B-3bgkA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		6 / 12 GLY A  31
GLY A 100
GLY A 128
HIS A  60
VAL A  57
PHE A  77
 None
 1.47A 5vimA-3bgkA:
3.8		 5vimA-3bgkA:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3A_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		5 / 12 MET A  97
GLY A  98
GLY A 100
ALA A 102
ILE A 126
 None
 1.12A 6b3aA-3bgkA:
undetectable		 6b3aA-3bgkA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B3B_A_SAMA701_0
(APRA
METHYLTRANSFERASE 1)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		5 / 12 MET A  97
GLY A  98
GLY A 100
ALA A 102
ILE A 126
 None
 1.13A 6b3bA-3bgkA:
3.6		 6b3bA-3bgkA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3M_B_ADNB502_2
(-)		 3bgk PUTATIVE
UNCHARACTERIZED
PROTEIN
(Streptococcus
mutans) 		4 / 4 GLN A 146
THR A 144
THR A 150
LEU A  96
 None
 1.48A 6f3mB-3bgkA:
6.8		 6f3mB-3bgkA:
20.39