SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bgy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q6I_A_FK5A301_1
(FKBP-TYPE
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKPA)		 3bgy POLYNUCLEOTIDE
5'-TRIPHOSPHATASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 9 TYR A 112
LEU A 116
ILE A 170
TYR A 172
ILE A 199
 None
 1.30A 1q6iA-3bgyA:
undetectable		 1q6iA-3bgyA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO5_A_CHDA131_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3bgy POLYNUCLEOTIDE
5'-TRIPHOSPHATASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 12 ILE A  12
ILE A  23
ILE A 137
VAL A  40
PHE A 232
 None
 1.14A 2qo5A-3bgyA:
1.6		 2qo5A-3bgyA:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HAV_A_SRYA403_1
(AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)		 3bgy POLYNUCLEOTIDE
5'-TRIPHOSPHATASE
(Acanthamoeba
polyphaga
mimivirus) 		4 / 8 SER A  31
ASP A 220
ASP A  29
TYR A  20
 None
 1.26A 3havA-3bgyA:
undetectable		 3havA-3bgyA:
24.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 3bgy POLYNUCLEOTIDE
5'-TRIPHOSPHATASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 12 GLU A 210
GLU A  39
VAL A 231
ASP A 189
ILE A 188
 None
 1.42A 3jayA-3bgyA:
undetectable		 3jayA-3bgyA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 3bgy POLYNUCLEOTIDE
5'-TRIPHOSPHATASE
(Acanthamoeba
polyphaga
mimivirus) 		5 / 11 PHE A 232
ILE A 137
TRP A 140
ILE A 221
ILE A 188
 None
 1.17A 5hw8A-3bgyA:
undetectable
5hw8D-3bgyA:
undetectable		 5hw8A-3bgyA:
21.76
5hw8D-3bgyA:
21.76