SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bh0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		5 / 12 LEU A 380
LEU A 374
ILE A 314
VAL A 361
ARG A 364
 None
 1.27A 1hrkB-3bh0A:
2.9		 1hrkB-3bh0A:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		5 / 11 LEU A 320
ALA A 353
SER A 355
LEU A 380
SER A 377
 None
 1.22A 1tz8A-3bh0A:
undetectable
1tz8B-3bh0A:
undetectable		 1tz8A-3bh0A:
19.41
1tz8B-3bh0A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_B_DESB128_1
(TRANSTHYRETIN)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		5 / 11 LEU A 380
SER A 377
LEU A 320
ALA A 353
SER A 355
 None
 1.19A 1tz8A-3bh0A:
undetectable
1tz8B-3bh0A:
undetectable		 1tz8A-3bh0A:
19.41
1tz8B-3bh0A:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		4 / 6 ARG A 258
ILE A 249
GLY A 247
ALA A 246
 None
 1.00A 1wmqA-3bh0A:
undetectable		 1wmqA-3bh0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		4 / 6 ARG A 258
ILE A 249
GLY A 247
ALA A 246
 None
 0.99A 1wmqB-3bh0A:
undetectable		 1wmqB-3bh0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		4 / 6 ARG A 258
ILE A 249
GLY A 247
ALA A 246
 None
 1.00A 1wpuA-3bh0A:
undetectable		 1wpuA-3bh0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		4 / 6 ARG A 258
ILE A 249
GLY A 247
ALA A 246
 None
 1.00A 1wpuB-3bh0A:
undetectable		 1wpuB-3bh0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		4 / 6 ARG A 258
ILE A 249
GLY A 247
ALA A 246
 None
 0.97A 1wrqA-3bh0A:
undetectable		 1wrqA-3bh0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		4 / 6 ARG A 258
ILE A 249
GLY A 247
ALA A 246
 None
 0.98A 1wrqB-3bh0A:
undetectable		 1wrqB-3bh0A:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YI4_A_ADNA306_1
(PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		5 / 10 LEU A 213
ALA A 216
ILE A 352
LEU A 354
ILE A 200
 None
 1.12A 1yi4A-3bh0A:
undetectable		 1yi4A-3bh0A:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		5 / 9 SER A 279
LEU A 213
ILE A 276
ALA A 246
GLY A 181
 None
 0.95A 2v0mB-3bh0A:
undetectable		 2v0mB-3bh0A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_1
(CYTOCHROME P450 3A4)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		5 / 12 SER A 279
LEU A 213
ILE A 276
ALA A 246
GLY A 181
 None
 0.98A 3nxuA-3bh0A:
undetectable		 3nxuA-3bh0A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		5 / 12 ILE A 175
GLY A 191
ILE A 311
VAL A 226
ASP A 224
 None
 0.87A 4a81A-3bh0A:
undetectable		 4a81A-3bh0A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HAJ_A_DXCA75_0
(PPCA)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		4 / 7 ILE A 200
LEU A 390
PHE A 432
GLY A 430
 None
 0.85A 4hajA-3bh0A:
undetectable		 4hajA-3bh0A:
12.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		5 / 12 LEU A 354
LEU A 199
ILE A 333
ILE A 336
LEU A 319
 None
 1.09A 4j24A-3bh0A:
undetectable		 4j24A-3bh0A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_C_ESTC600_1
(ESTROGEN RECEPTOR
BETA)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		5 / 12 LEU A 354
LEU A 199
ILE A 333
ILE A 336
LEU A 319
 None
 1.09A 4j24C-3bh0A:
undetectable		 4j24C-3bh0A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_B_ESTB600_1
(ESTROGEN RECEPTOR
BETA)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		5 / 12 LEU A 354
LEU A 199
ILE A 333
ILE A 336
LEU A 319
 None
 1.12A 4j26B-3bh0A:
undetectable		 4j26B-3bh0A:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTH_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		3 / 3 ASP A 186
LEU A 185
PHE A 182
 None
 0.43A 4pthA-3bh0A:
undetectable		 4pthA-3bh0A:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		4 / 6 ASP A 373
ILE A 409
ARG A 368
TYR A 391
 None
 1.00A 5igyA-3bh0A:
undetectable		 5igyA-3bh0A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		4 / 6 ASP A 373
ILE A 409
ARG A 368
TYR A 391
 None
 1.02A 5iwuA-3bh0A:
undetectable		 5iwuA-3bh0A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UBB_A_SAMA301_0
(ALPHA N-TERMINAL
PROTEIN
METHYLTRANSFERASE 1B)		 3bh0 DNAB-LIKE
REPLICATIVE HELICASE
(Bacillus
phage
SPP1) 		5 / 12 VAL A 198
SER A 290
LEU A 320
HIS A 229
LEU A 231
 None
 1.27A 5ubbA-3bh0A:
2.8		 5ubbA-3bh0A:
22.09