SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bh1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 10 ALA A 288
PHE A  52
LEU A  33
VAL A 175
ILE A  20
 None
 0.86A 1claA-3bh1A:
undetectable		 1claA-3bh1A:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EUP_A_ASDA452_1
(CYTOCHROME P450ERYF)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 8 PHE A 475
SER A 384
LEU A 388
LEU A 391
 None
None
GOL  A 507 ( 4.5A)
None
 0.85A 1eupA-3bh1A:
undetectable		 1eupA-3bh1A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 8 GLY A 107
ARG A 104
LEU A 109
ASP A 101
 None
 0.93A 1jg4A-3bh1A:
undetectable		 1jg4A-3bh1A:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TLM_A_MILA128_1
(TRANSTHYRETIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		3 / 3 LEU A 427
LEU A 380
SER A 377
 None
 0.68A 1tlmA-3bh1A:
undetectable		 1tlmA-3bh1A:
13.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZX_A_TRPA602_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 8 LEU A 366
ILE A 364
LEU A 391
HIS A 393
 None
 0.86A 2azxA-3bh1A:
2.8		 2azxA-3bh1A:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 5 TYR A  12
ARG A   9
MET A  60
LEU A  61
 None
 1.40A 2eimW-3bh1A:
undetectable		 2eimW-3bh1A:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HZQ_A_STRA300_1
(APOLIPOPROTEIN D)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 7 ALA A 288
ASN A 286
PHE A 208
LEU A  49
 None
 1.01A 2hzqA-3bh1A:
undetectable		 2hzqA-3bh1A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 5 TYR A  12
ARG A   9
MET A  60
LEU A  61
 None
 1.38A 3ag1J-3bh1A:
undetectable		 3ag1J-3bh1A:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 9 ALA A 288
PHE A  52
LEU A  33
VAL A 175
ILE A  20
 None
 0.86A 3claA-3bh1A:
undetectable		 3claA-3bh1A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 11 LEU A 436
ALA A 440
ASN A 445
ALA A 395
LYS A 392
 None
None
None
None
GOL  A 507 (-3.0A)
 1.21A 3e22D-3bh1A:
undetectable		 3e22D-3bh1A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_A_CLYA900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 10 GLU A  10
GLU A  14
PHE A   7
SER A 293
ILE A   5
 None
 1.28A 3jz0A-3bh1A:
0.0		 3jz0A-3bh1A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZ0_B_CLYB900_1
(LINCOSAMIDE
NUCLEOTIDYLTRANSFERA
SE)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 8 GLU A  10
GLU A  14
PHE A   7
SER A 293
ILE A   5
 None
 1.25A 3jz0B-3bh1A:
undetectable		 3jz0B-3bh1A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 6 ILE A  70
VAL A  68
LEU A 173
LEU A  33
 None
 0.70A 3kp6A-3bh1A:
undetectable
3kp6B-3bh1A:
undetectable		 3kp6A-3bh1A:
17.17
3kp6B-3bh1A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_A_OBNA1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 11 PRO A 212
ASN A 237
VAL A 333
ALA A 330
ILE A 306
 None
 1.27A 3n23A-3bh1A:
undetectable		 3n23A-3bh1A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_A_FUNA201_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 11 ARG A 308
SER A 484
VAL A 347
VAL A 346
ILE A 307
 None
 1.40A 3rf4A-3bh1A:
undetectable
3rf4C-3bh1A:
undetectable		 3rf4A-3bh1A:
12.43
3rf4C-3bh1A:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 11 ILE A 307
ARG A 308
SER A 484
VAL A 347
VAL A 346
 None
 1.38A 3rf4A-3bh1A:
undetectable
3rf4B-3bh1A:
undetectable		 3rf4A-3bh1A:
12.43
3rf4B-3bh1A:
12.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 7 LEU A 427
LEU A 379
GLU A 410
PRO A 406
ILE A 409
 None
 1.43A 3s56B-3bh1A:
undetectable		 3s56B-3bh1A:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		3 / 3 LEU A 271
HIS A 197
MET A 272
 None
 0.92A 3thrD-3bh1A:
1.5		 3thrD-3bh1A:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_B_ACHB301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 8 TYR A 166
THR A 170
TYR A  32
ARG A 171
 None
 1.47A 3wipB-3bh1A:
undetectable
3wipC-3bh1A:
undetectable		 3wipB-3bh1A:
18.09
3wipC-3bh1A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_C_ACHC301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 8 TYR A 166
THR A 170
TYR A  32
ARG A 171
 None
 1.47A 3wipC-3bh1A:
undetectable
3wipD-3bh1A:
undetectable		 3wipC-3bh1A:
18.09
3wipD-3bh1A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_F_ACHF301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 7 TYR A 166
THR A 170
TYR A  32
ARG A 171
 None
 1.46A 3wipF-3bh1A:
undetectable
3wipG-3bh1A:
undetectable		 3wipF-3bh1A:
18.09
3wipG-3bh1A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 8 LEU A 190
PRO A 276
SER A 275
VAL A 285
GLY A 284
 None
 1.40A 4klrB-3bh1A:
undetectable		 4klrB-3bh1A:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 12 LEU A 271
ARG A 270
ALA A 260
HIS A 195
TYR A 148
 None
 1.29A 4l9qA-3bh1A:
undetectable		 4l9qA-3bh1A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 8 LEU A  27
VAL A 193
TYR A 205
LEU A  31
 None
 1.01A 4pwdA-3bh1A:
undetectable		 4pwdA-3bh1A:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 12 LEU A 415
THR A 414
ILE A 412
LEU A 420
LEU A 427
 None
 0.95A 5nfjA-3bh1A:
undetectable		 5nfjA-3bh1A:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 9 ALA A 395
ILE A 364
LEU A 366
ILE A 372
ALA A 449
 None
 1.00A 5nunA-3bh1A:
undetectable		 5nunA-3bh1A:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_1
(TETRACYCLINE
DESTRUCTASE TET(50))		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 5 ASP A  95
ARG A  98
ARG A  85
LEU A  61
 None
 1.43A 5tuiB-3bh1A:
undetectable		 5tuiB-3bh1A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		3 / 3 GLU A 165
TYR A 166
ARG A 199
 None
 0.60A 5uunA-3bh1A:
undetectable		 5uunA-3bh1A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		3 / 3 GLU A 165
TYR A 166
ARG A 199
 None
 0.49A 5uunB-3bh1A:
undetectable		 5uunB-3bh1A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB308_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		3 / 3 LEU A  33
ILE A  20
TYR A  12
 None
 0.63A 5uunB-3bh1A:
undetectable		 5uunB-3bh1A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 5 TYR A  12
ARG A   9
MET A  60
LEU A  61
 None
 1.44A 5x19J-3bh1A:
undetectable		 5x19J-3bh1A:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 5 TYR A  12
ARG A   9
MET A  60
LEU A  61
 None
 1.32A 5x1fW-3bh1A:
undetectable		 5x1fW-3bh1A:
6.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 8 PRO A 425
THR A 414
THR A 417
PRO A 406
 None
 1.35A 5x2sI-3bh1A:
undetectable
5x2sJ-3bh1A:
undetectable
5x2sK-3bh1A:
undetectable		 5x2sI-3bh1A:
16.89
5x2sJ-3bh1A:
15.58
5x2sK-3bh1A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		4 / 6 TYR A 254
LEU A 264
GLU A  34
LEU A 186
 None
None
GOL  A 506 (-3.2A)
GOL  A 506 (-4.3A)
 1.38A 5xooA-3bh1A:
undetectable		 5xooA-3bh1A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 12 LEU A 453
LEU A 478
SER A 408
LEU A 450
LEU A 403
 None
None
None
None
GOL  A 507 (-4.2A)
 1.00A 6ew0B-3bh1A:
undetectable		 6ew0B-3bh1A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 12 LEU A 453
LEU A 478
SER A 408
LEU A 450
LEU A 403
 None
None
None
None
GOL  A 507 (-4.2A)
 1.00A 6ew0D-3bh1A:
undetectable		 6ew0D-3bh1A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 12 LEU A 453
LEU A 478
SER A 408
LEU A 450
LEU A 403
 None
None
None
None
GOL  A 507 (-4.2A)
 1.00A 6ew0H-3bh1A:
undetectable		 6ew0H-3bh1A:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 3bh1 UPF0371 PROTEIN
DIP2346
(Corynebacterium
diphtheriae) 		5 / 12 LEU A 453
LEU A 478
SER A 408
LEU A 450
LEU A 403
 None
None
None
None
GOL  A 507 (-4.2A)
 0.99A 6ew0I-3bh1A:
undetectable		 6ew0I-3bh1A:
11.89