SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bh2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LWC_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		5 / 11 PRO A  50
LEU A  51
TYR A 240
LEU A 168
TYR A  92
 None
 1.50A 1lwcA-3bh2A:
undetectable		 1lwcA-3bh2A:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PLW_A_SAMA203_0
(RIBOSOMAL RNA
METHYLTRANSFERASE,
PUTATIVE)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		5 / 12 TYR A 135
GLY A 136
ILE A  62
ALA A 141
LEU A 203
 None
 1.03A 2plwA-3bh2A:
undetectable		 2plwA-3bh2A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		4 / 7 LYS A 169
ILE A 184
MET A  96
ARG A  21
 None
 1.32A 3ik3B-3bh2A:
undetectable		 3ik3B-3bh2A:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEE_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		5 / 12 PRO A  50
LEU A  51
TYR A 240
LEU A 168
TYR A  92
 None
 1.47A 3meeA-3bh2A:
undetectable		 3meeA-3bh2A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		4 / 5 LYS A 169
ILE A 184
MET A  96
ARG A  21
 None
 1.31A 3pyyB-3bh2A:
undetectable		 3pyyB-3bh2A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		3 / 3 LEU A  71
MET A  65
ASP A 230
 None
 0.86A 3v5wA-3bh2A:
undetectable		 3v5wA-3bh2A:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_A_C2FA302_0
(THYMIDYLATE SYNTHASE)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		5 / 11 SER A 224
ILE A  34
LEU A 213
GLY A 131
PHE A  32
 None
 1.22A 4fogA-3bh2A:
undetectable		 4fogA-3bh2A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		5 / 11 SER A 224
ILE A  34
LEU A 213
GLY A 131
PHE A  32
 None
 1.36A 4fogC-3bh2A:
undetectable		 4fogC-3bh2A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		4 / 8 SER A 126
ASP A 127
VAL A 130
THR A 144
 None
 1.15A 4lnwA-3bh2A:
undetectable		 4lnwA-3bh2A:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		5 / 12 THR A 144
GLY A 131
ASP A 125
ILE A  34
SER A 224
 None
 1.31A 4pooB-3bh2A:
undetectable		 4pooB-3bh2A:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		5 / 9 PRO A  50
LEU A  51
TYR A 240
LEU A 168
TYR A  92
 None
 1.50A 4puoA-3bh2A:
0.6		 4puoA-3bh2A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HBM_A_NVPA601_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		5 / 11 PRO A  50
LEU A  51
TYR A 240
LEU A 168
TYR A  92
 None
 1.43A 5hbmA-3bh2A:
undetectable		 5hbmA-3bh2A:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		4 / 7 ILE A  53
LEU A  43
LEU A 216
PRO A  82
 None
 1.02A 5u4sA-3bh2A:
undetectable		 5u4sA-3bh2A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_C_GM4C301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3bh2 ACETOACETATE
DECARBOXYLASE
(Clostridium
acetobutylicum) 		5 / 11 VAL A 106
TYR A  74
LEU A  98
GLU A  76
THR A  68
 None
 1.43A 6dk1C-3bh2A:
undetectable		 6dk1C-3bh2A:
18.92