SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bhi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_A_DVAA6_0
(GRAMICIDIN A)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		3 / 3 ALA A 224
VAL A 202
TRP A 276
 None
 0.92A 1jnoA-3bhiA:
undetectable		 1jnoA-3bhiA:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JNO_B_DVAB6_0
(GRAMICIDIN A)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		3 / 3 ALA A 224
VAL A 202
TRP A 276
 None
 0.92A 1jnoB-3bhiA:
undetectable		 1jnoB-3bhiA:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_A_DVAA6_0
(GRAMICIDIN A)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		3 / 3 ALA A 224
VAL A 202
TRP A 276
 None
 0.95A 1nrmA-3bhiA:
undetectable		 1nrmA-3bhiA:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRM_B_DVAB6_0
(GRAMICIDIN A)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		3 / 3 ALA A 224
VAL A 202
TRP A 276
 None
 0.95A 1nrmB-3bhiA:
undetectable		 1nrmB-3bhiA:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_A_DVAA6_0
(GRAMICIDIN A)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		3 / 3 ALA A 224
VAL A 202
TRP A 276
 None
 0.94A 1nruA-3bhiA:
undetectable		 1nruA-3bhiA:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NRU_B_DVAB6_0
(GRAMICIDIN A)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		3 / 3 ALA A 224
VAL A 202
TRP A 276
 None
 0.94A 1nruB-3bhiA:
undetectable		 1nruB-3bhiA:
4.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		5 / 12 LEU A 255
VAL A 251
VAL A  32
LEU A  49
LEU A  54
 None
 1.14A 1s19A-3bhiA:
undetectable		 1s19A-3bhiA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_B_ERYB1399_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		5 / 12 ASN A 136
VAL A 135
LEU A  61
ALA A   7
ASP A 119
 None
 1.39A 2iyfB-3bhiA:
6.1		 2iyfB-3bhiA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_A_MIYA2001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		4 / 8 SER A 204
GLY A  91
ASN A  88
PHE A 115
 None
NAP  A 309 (-4.0A)
None
None
 0.92A 3aodA-3bhiA:
undetectable		 3aodA-3bhiA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I45_A_NIOA500_1
(TWIN-ARGININE
TRANSLOCATION
PATHWAY SIGNAL
PROTEIN)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		4 / 8 LEU A   8
TYR A  80
PHE A  75
LEU A  72
 None
 0.93A 3i45A-3bhiA:
4.8		 3i45A-3bhiA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_2
(ADENOSINE KINASE)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		4 / 5 SER A 139
ILE A  16
TYR A 193
GLY A 228
 NAP  A 309 ( 3.8A)
NAP  A 309 (-3.8A)
NAP  A 309 (-4.8A)
CL  A 308 ( 3.9A)
 0.94A 3uboB-3bhiA:
5.5		 3uboB-3bhiA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		5 / 12 ILE A  20
GLY A  12
ILE A  63
ASN A 136
LEU A   8
 None
NAP  A 309 ( 4.8A)
NAP  A 309 (-4.2A)
None
None
 0.93A 4a81A-3bhiA:
undetectable		 4a81A-3bhiA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		3 / 3 SER A 191
ALA A 192
THR A 109
 None
 0.63A 5n0xB-3bhiA:
undetectable		 5n0xB-3bhiA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		4 / 6 ASN A 136
ALA A 224
PRO A 250
VAL A 135
 None
 1.05A 5umd2-3bhiA:
undetectable
5umdF-3bhiA:
undetectable		 5umd2-3bhiA:
13.77
5umdF-3bhiA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WQP_A_NCAA302_0
(PROBABLE
DEHYDROGENASE)		 3bhi CARBONYL REDUCTASE
[NADPH] 1
(Homo
sapiens) 		5 / 8 SER A 139
MET A 141
TYR A 193
TRP A 229
MET A 234
 NAP  A 309 ( 3.8A)
None
NAP  A 309 (-4.8A)
None
NAP  A 309 (-3.6A)
 0.62A 5wqpA-3bhiA:
24.9		 5wqpA-3bhiA:
25.86