SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bhn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3bhn THIJ/PFPI DOMAIN
PROTEIN
(Shewanella
loihica) 		4 / 5 PHE A  83
THR A  38
LEU A  36
ALA A  86
 EDO  A 219 ( 4.2A)
EDO  A 219 (-3.3A)
None
None
 1.15A 2e1qD-3bhnA:
undetectable		 2e1qD-3bhnA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3bhn THIJ/PFPI DOMAIN
PROTEIN
(Shewanella
loihica) 		4 / 5 PHE A 166
THR A  27
LEU A  24
ALA A 162
 None
 1.16A 2e1qD-3bhnA:
undetectable		 2e1qD-3bhnA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_D_SNLD4001_2
(MINERALOCORTICOID
RECEPTOR)		 3bhn THIJ/PFPI DOMAIN
PROTEIN
(Shewanella
loihica) 		4 / 5 LEU A 157
LEU A  19
CYH A 100
THR A 119
 None
 1.41A 2oaxD-3bhnA:
1.8		 2oaxD-3bhnA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_0
(PCZA361.24)		 3bhn THIJ/PFPI DOMAIN
PROTEIN
(Shewanella
loihica) 		5 / 12 ALA A 148
GLY A 150
LEU A 139
SER A 103
GLY A 102
 None
 1.10A 3g2oA-3bhnA:
undetectable		 3g2oA-3bhnA:
25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LK0_D_Z80D92_1
(PROTEIN S100-B)		 3bhn THIJ/PFPI DOMAIN
PROTEIN
(Shewanella
loihica) 		3 / 3 HIS A  43
PHE A  17
PHE A  18
 None
EDO  A 220 (-4.8A)
None
 0.57A 3lk0D-3bhnA:
undetectable		 3lk0D-3bhnA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_A_SAMA201_0
(YAEB-LIKE PROTEIN
RPA0152)		 3bhn THIJ/PFPI DOMAIN
PROTEIN
(Shewanella
loihica) 		5 / 12 LEU A 154
THR A  68
SER A  69
CYH A 151
LEU A 152
 None
 1.37A 3okxA-3bhnA:
undetectable		 3okxA-3bhnA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3bhn THIJ/PFPI DOMAIN
PROTEIN
(Shewanella
loihica) 		5 / 11 GLY A 102
ILE A  99
GLY A   5
PHE A   9
PHE A  83
 None
None
None
None
EDO  A 219 ( 4.2A)
 0.99A 4qoiA-3bhnA:
5.3
4qoiB-3bhnA:
5.2		 4qoiA-3bhnA:
22.96
4qoiB-3bhnA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_A_LURA706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3bhn THIJ/PFPI DOMAIN
PROTEIN
(Shewanella
loihica) 		5 / 12 VAL A  64
LEU A  66
LEU A 139
VAL A 158
LEU A 165
 None
 1.11A 4rrxA-3bhnA:
undetectable		 4rrxA-3bhnA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRX_B_LURB706_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3bhn THIJ/PFPI DOMAIN
PROTEIN
(Shewanella
loihica) 		5 / 12 VAL A  64
LEU A  66
LEU A 139
VAL A 158
LEU A 165
 None
 1.11A 4rrxB-3bhnA:
undetectable		 4rrxB-3bhnA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3bhn THIJ/PFPI DOMAIN
PROTEIN
(Shewanella
loihica) 		4 / 9 GLU A 199
LEU A 161
LEU A  95
ILE A  96
 None
None
EDO  A 218 (-4.3A)
None
 0.98A 4xtaA-3bhnA:
1.8		 4xtaA-3bhnA:
22.26