SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bho'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		5 / 12 LEU A  84
LEU A  96
LEU A 193
MET A 125
ILE A 128
 None
 1.07A 1g50B-3bhoA:
undetectable		 1g50B-3bhoA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		5 / 11 LEU A  84
LEU A  96
LEU A 193
MET A 125
ILE A 128
 None
 1.07A 1g50C-3bhoA:
undetectable		 1g50C-3bhoA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		5 / 9 LEU A  84
LEU A 215
GLU A  81
ILE A 145
PHE A 224
 None
 1.35A 1gx8A-3bhoA:
undetectable		 1gx8A-3bhoA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QVT_A_PRLA311_0
(TRANSCRIPTIONAL
REGULATOR QACR)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		4 / 8 LEU A  53
GLU A  55
THR A  79
ILE A 128
 None
 0.80A 1qvtA-3bhoA:
undetectable		 1qvtA-3bhoA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		5 / 7 LYS A 192
LEU A  97
GLN A  98
LEU A 129
PHE A 185
 None
 1.37A 1v55P-3bhoA:
undetectable
1v55W-3bhoA:
undetectable		 1v55P-3bhoA:
19.00
1v55W-3bhoA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		5 / 7 LYS A 192
LEU A  97
GLN A  98
LEU A 129
PHE A 185
 None
 1.23A 2dysC-3bhoA:
undetectable
2dysJ-3bhoA:
undetectable		 2dysC-3bhoA:
19.00
2dysJ-3bhoA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		5 / 7 LYS A 192
LEU A  97
GLN A  98
LEU A 129
PHE A 185
 None
 1.40A 2eijP-3bhoA:
undetectable
2eijW-3bhoA:
undetectable		 2eijP-3bhoA:
19.00
2eijW-3bhoA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		5 / 8 LYS A 192
LEU A  97
GLN A  98
LEU A 129
PHE A 185
 None
 1.36A 2eilP-3bhoA:
undetectable
2eilW-3bhoA:
undetectable		 2eilP-3bhoA:
19.00
2eilW-3bhoA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		5 / 12 LEU A  96
ALA A 195
LEU A 198
LEU A  39
PHE A 185
 None
 1.41A 2oaxF-3bhoA:
undetectable		 2oaxF-3bhoA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		5 / 7 LYS A 192
LEU A  97
GLN A  98
LEU A 129
PHE A 185
 None
 1.34A 2zxwC-3bhoA:
undetectable
2zxwJ-3bhoA:
undetectable		 2zxwC-3bhoA:
19.00
2zxwJ-3bhoA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		5 / 8 LYS A 192
LEU A  97
GLN A  98
LEU A 129
PHE A 185
 None
 1.39A 3asoC-3bhoA:
undetectable
3asoJ-3bhoA:
undetectable		 3asoC-3bhoA:
19.00
3asoJ-3bhoA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEL_D_QELD2_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE [NMDA]
RECEPTOR SUBUNIT
EPSILON-2)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		4 / 5 TYR A  45
THR A  46
PHE A  47
LEU A 129
 None
 1.23A 3qelC-3bhoA:
undetectable		 3qelC-3bhoA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		5 / 12 LEU A  84
LEU A  96
LEU A 193
MET A 125
LEU A 215
 None
 1.15A 4zn7A-3bhoA:
undetectable		 4zn7A-3bhoA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3bho CLEAVAGE AND
POLYADENYLATION
SPECIFICITY FACTOR
SUBUNIT 5
(Homo
sapiens) 		4 / 6 LYS A 192
GLN A  98
LEU A 129
PHE A 185
 None
 1.17A 6nmpC-3bhoA:
undetectable
6nmpJ-3bhoA:
undetectable		 6nmpC-3bhoA:
19.00
6nmpJ-3bhoA:
19.48