SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bhq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 11 LEU A  91
LEU A  94
ALA A  95
LEU A 169
MET A 168
 None
 1.11A 1g50A-3bhqA:
undetectable		 1g50A-3bhqA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 12 PHE A 201
MET A  87
GLY A  90
LEU A  91
LEU A  94
 None
 1.02A 2hw2A-3bhqA:
undetectable		 2hw2A-3bhqA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 12 VAL A  48
LEU A  58
ALA A  10
GLY A  42
ALA A  41
 None
 1.04A 3ln1A-3bhqA:
0.3		 3ln1A-3bhqA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 12 VAL A  48
LEU A  58
ALA A  10
GLY A  42
ALA A  41
 None
 1.04A 3ln1B-3bhqA:
0.8		 3ln1B-3bhqA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 12 VAL A  48
LEU A  58
ALA A  10
GLY A  42
ALA A  41
 None
 1.03A 3ln1C-3bhqA:
undetectable		 3ln1C-3bhqA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 12 VAL A  48
LEU A  58
ALA A  10
GLY A  42
ALA A  41
 None
 1.04A 3ln1D-3bhqA:
undetectable		 3ln1D-3bhqA:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_B_ESLB700_1
(ESTROGEN RECEPTOR)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 12 LEU A  91
LEU A  94
ALA A  95
LEU A 169
MET A 168
 None
 0.92A 3q95B-3bhqA:
undetectable		 3q95B-3bhqA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_A_ESTA2000_1
(ESTROGEN RECEPTOR)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 12 LEU A  91
LEU A  94
ALA A  95
LEU A 169
MET A 168
 None
 0.93A 4pxmA-3bhqA:
undetectable		 4pxmA-3bhqA:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 11 LEU A 165
LEU A  91
GLU A 199
ALA A 203
LEU A 202
 None
 1.13A 4wg0J-3bhqA:
undetectable
4wg0K-3bhqA:
undetectable
4wg0L-3bhqA:
undetectable		 4wg0J-3bhqA:
5.08
4wg0K-3bhqA:
5.08
4wg0L-3bhqA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 11 LEU A 165
LEU A  91
GLU A 199
ALA A 203
TYR A 205
 None
 1.01A 4wg0J-3bhqA:
undetectable
4wg0K-3bhqA:
undetectable
4wg0L-3bhqA:
undetectable		 4wg0J-3bhqA:
5.08
4wg0K-3bhqA:
5.08
4wg0L-3bhqA:
5.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 10 LEU A 169
LEU A 170
GLY A 167
SER A 163
ILE A  99
 None
 0.97A 4xj7C-3bhqA:
undetectable
4xj7D-3bhqA:
undetectable		 4xj7C-3bhqA:
22.61
4xj7D-3bhqA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 12 VAL A  48
LEU A  58
ALA A  10
GLY A  42
ALA A  41
 None
 0.99A 5jw1A-3bhqA:
2.2		 5jw1A-3bhqA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 3bhq TRANSCRIPTIONAL
REGULATOR
(Mesorhizobium
japonicum) 		5 / 12 LEU A  91
LEU A  94
ALA A  95
LEU A 169
MET A 168
 None
 0.97A 5toaA-3bhqA:
undetectable		 5toaA-3bhqA:
23.14