SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bhw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 10 GLU A 158
LEU A  15
LEU A  17
ILE A  23
LEU A  60
 None
 1.41A 1a52A-3bhwA:
undetectable		 1a52A-3bhwA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 10 GLU A 158
LEU A  15
LEU A  17
ILE A  23
LEU A  60
 None
 1.38A 1a52B-3bhwA:
undetectable		 1a52B-3bhwA:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_A_ESTA600_1
(ESTROGEN RECEPTOR)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 9 GLU A 158
LEU A  15
LEU A  17
ILE A  23
LEU A  60
 None
 1.45A 1ereA-3bhwA:
undetectable		 1ereA-3bhwA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_B_ESTB600_1
(ESTROGEN RECEPTOR)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 9 GLU A 158
LEU A  15
LEU A  17
ILE A  23
LEU A  60
 None
 1.45A 1ereB-3bhwA:
undetectable		 1ereB-3bhwA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_C_ESTC600_1
(ESTROGEN RECEPTOR)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 9 GLU A 158
LEU A  15
LEU A  17
ILE A  23
LEU A  60
 None
 1.44A 1ereC-3bhwA:
undetectable		 1ereC-3bhwA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERE_D_ESTD600_1
(ESTROGEN RECEPTOR)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 9 GLU A 158
LEU A  15
LEU A  17
ILE A  23
LEU A  60
 None
 1.45A 1ereD-3bhwA:
undetectable		 1ereD-3bhwA:
23.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 8 LEU A 127
VAL A 152
LEU A  98
TYR A 126
 None
 0.90A 1jlbA-3bhwA:
undetectable		 1jlbA-3bhwA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 8 LEU A 127
VAL A 152
LEU A  98
TYR A 126
 None
 0.87A 1s1xA-3bhwA:
undetectable		 1s1xA-3bhwA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		5 / 10 LEU A  65
ILE A  10
GLY A  11
GLY A  13
VAL A  88
 None
 0.91A 1sdtA-3bhwA:
undetectable		 1sdtA-3bhwA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		6 / 12 ILE A  93
ALA A  91
ALA A  92
LEU A  15
PHE A  89
ALA A  87
 None
 1.49A 1xiuB-3bhwA:
undetectable		 1xiuB-3bhwA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DH0_A_SAMA220_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 8 ARG A 133
TYR A   6
GLN A 110
MET A 122
 None
 1.18A 3dh0A-3bhwA:
undetectable		 3dh0A-3bhwA:
25.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 5 ARG A 154
ARG A  64
ILE A  93
PHE A  89
 None
 1.22A 3ln1D-3bhwA:
undetectable		 3ln1D-3bhwA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 8 LEU A 127
VAL A 152
LEU A  98
TYR A 126
 None
 0.95A 3v81C-3bhwA:
undetectable		 3v81C-3bhwA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 7 LEU A 127
VAL A 152
LEU A  98
TYR A 126
 None
 0.92A 4b3qA-3bhwA:
undetectable		 4b3qA-3bhwA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_1
(METHYLTRANSFERASE
NSUN4)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		3 / 3 ASP A 109
ARG A 112
ASP A 104
 None
 0.67A 4fp9A-3bhwA:
undetectable		 4fp9A-3bhwA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_1
(METHYLTRANSFERASE
NSUN4)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		3 / 3 ASP A 109
ARG A 112
ASP A 104
 None
 0.52A 4fp9C-3bhwA:
undetectable		 4fp9C-3bhwA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_1
(METHYLTRANSFERASE
NSUN4)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		3 / 3 ASP A 109
ARG A 112
ASP A 104
 None
 0.55A 4fp9F-3bhwA:
undetectable		 4fp9F-3bhwA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 8 LEU A 127
VAL A 152
LEU A  98
TYR A 126
 None
 0.96A 4puoC-3bhwA:
undetectable		 4puoC-3bhwA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 7 TYR A 161
ALA A  92
ILE A 195
LEU A 103
 None
 0.90A 4uymA-3bhwA:
undetectable		 4uymA-3bhwA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 7 TYR A 161
ALA A  92
ILE A 195
LEU A 103
 None
 1.02A 4uymB-3bhwA:
undetectable		 4uymB-3bhwA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BZO_C_FI8C1201_2
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
RNA POLYMERASE SIGMA
FACTOR SIGA)		 3bhw UNCHARACTERIZED
PROTEIN
(Magnetospirillum
magneticum) 		4 / 4 LEU A 170
ASP A 117
GLN A 110
VAL A  88
 None
 1.45A 6bzoF-3bhwA:
undetectable		 6bzoF-3bhwA:
17.21