SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bin'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 3bin BAND 4.1-LIKE
PROTEIN 3
(Homo
sapiens) 		5 / 11 GLY A 297
TYR A 296
PHE A 386
PHE A 387
HIS A 383
 None
 1.38A 1w76A-3binA:
undetectable		 1w76A-3binA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_B_8MOB501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3bin BAND 4.1-LIKE
PROTEIN 3
(Homo
sapiens) 		5 / 11 PHE A 332
ILE A 363
GLY A 364
ILE A 311
LEU A 313
 None
 1.07A 1z11B-3binA:
undetectable		 1z11B-3binA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ROX_B_T44B128_1
(TRANSTHYRETIN)		 3bin BAND 4.1-LIKE
PROTEIN 3
(Homo
sapiens) 		4 / 6 LYS A 266
GLU A 269
LEU A 225
THR A 260
 None
 1.06A 2roxB-3binA:
undetectable		 2roxB-3binA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_0
(GLYCINE
N-METHYLTRANSFERASE)		 3bin BAND 4.1-LIKE
PROTEIN 3
(Homo
sapiens) 		4 / 6 SER A 235
LEU A 237
THR A 232
ARG A 210
 None
 0.74A 3thrB-3binA:
undetectable		 3thrB-3binA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 3bin BAND 4.1-LIKE
PROTEIN 3
(Homo
sapiens) 		4 / 6 MET A 295
ILE A 340
ILE A 349
VAL A 337
 None
 0.98A 4olmA-3binA:
undetectable		 4olmA-3binA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_A_X2NA590_1
(CYP51 VARIANT1)		 3bin BAND 4.1-LIKE
PROTEIN 3
(Homo
sapiens) 		5 / 12 ALA A 280
LEU A 145
PHE A 136
GLY A 152
LEU A 117
 None
 1.17A 5fsaA-3binA:
undetectable		 5fsaA-3binA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 3bin BAND 4.1-LIKE
PROTEIN 3
(Homo
sapiens) 		5 / 11 VAL A 186
THR A 154
TYR A 150
PRO A 190
LEU A 205
 None
 1.47A 5jh7B-3binA:
undetectable		 5jh7B-3binA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 3bin BAND 4.1-LIKE
PROTEIN 3
(Homo
sapiens) 		5 / 11 VAL A 186
THR A 154
TYR A 150
PRO A 190
LEU A 205
 None
 1.47A 5jh7D-3binA:
undetectable		 5jh7D-3binA:
20.84