SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bit'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_A_DVAA8_0
(GRAMICIDIN A)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		3 / 3 VAL A 175
TRP A 173
TRP A  54
 None
 1.35A 1c4dA-3bitA:
undetectable
1c4dB-3bitA:
undetectable		 1c4dA-3bitA:
5.83
1c4dB-3bitA:
5.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 ILE A  98
LYS A  12
ALA A  87
VAL A  72
 None
 1.04A 1hk1A-3bitA:
undetectable		 1hk1A-3bitA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.48A 1k2rA-3bitA:
undetectable
1k2rB-3bitA:
undetectable		 1k2rA-3bitA:
23.65
1k2rB-3bitA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.48A 1k2rA-3bitA:
undetectable
1k2rB-3bitA:
undetectable		 1k2rA-3bitA:
23.65
1k2rB-3bitA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.48A 1k2sA-3bitA:
undetectable
1k2sB-3bitA:
undetectable		 1k2sA-3bitA:
23.65
1k2sB-3bitA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 1k2tA-3bitA:
undetectable
1k2tB-3bitA:
undetectable		 1k2tA-3bitA:
23.65
1k2tB-3bitA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 1k2tA-3bitA:
undetectable
1k2tB-3bitA:
undetectable		 1k2tA-3bitA:
23.65
1k2tB-3bitA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.47A 1k2uA-3bitA:
undetectable
1k2uB-3bitA:
undetectable		 1k2uA-3bitA:
23.65
1k2uB-3bitA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 1k2uA-3bitA:
undetectable
1k2uB-3bitA:
undetectable		 1k2uA-3bitA:
23.65
1k2uB-3bitA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 1lzxA-3bitA:
undetectable
1lzxB-3bitA:
undetectable		 1lzxA-3bitA:
23.65
1lzxB-3bitA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 1mmwA-3bitA:
undetectable
1mmwB-3bitA:
undetectable		 1mmwA-3bitA:
23.65
1mmwB-3bitA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 1om4A-3bitA:
undetectable
1om4B-3bitA:
undetectable		 1om4A-3bitA:
23.51
1om4B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 8 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.47A 1om5A-3bitA:
undetectable
1om5B-3bitA:
undetectable		 1om5A-3bitA:
23.55
1om5B-3bitA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.48A 1om5A-3bitA:
undetectable
1om5B-3bitA:
undetectable		 1om5A-3bitA:
23.55
1om5B-3bitA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 1p6hA-3bitA:
undetectable
1p6hB-3bitA:
undetectable		 1p6hA-3bitA:
23.55
1p6hB-3bitA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 1p6iA-3bitA:
undetectable
1p6iB-3bitA:
undetectable		 1p6iA-3bitA:
23.55
1p6iB-3bitA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 1rs7A-3bitA:
undetectable
1rs7B-3bitA:
undetectable		 1rs7A-3bitA:
23.55
1rs7B-3bitA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC2_E_NCAE509_0
(NAD-DEPENDENT
DEACETYLASE 2)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 ASP A 384
GLU A 343
ARG A 336
LYS A 339
 None
 1.11A 1yc2A-3bitA:
undetectable
1yc2B-3bitA:
undetectable
1yc2E-3bitA:
undetectable		 1yc2A-3bitA:
19.65
1yc2B-3bitA:
19.65
1yc2E-3bitA:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_B_H4BB920_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.45A 1zvlA-3bitA:
undetectable
1zvlB-3bitA:
1.1		 1zvlA-3bitA:
22.89
1zvlB-3bitA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA502_1
(CYTOCHROME P450 2B4)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 12 LEU A  84
LEU A   4
ASN A 296
LEU A  55
PHE A  11
 None
 1.07A 2bdmA-3bitA:
undetectable		 2bdmA-3bitA:
22.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 225
LEU A 231
GLY A 190
SER A 188
ILE A 292
 None
 1.14A 2e7fA-3bitA:
undetectable		 2e7fA-3bitA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 225
LEU A 231
GLY A 190
SER A 188
ILE A 292
 None
 1.13A 2e7fB-3bitA:
undetectable		 2e7fB-3bitA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 2g6hA-3bitA:
undetectable
2g6hB-3bitA:
undetectable		 2g6hA-3bitA:
23.60
2g6hB-3bitA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 2g6kA-3bitA:
undetectable
2g6kB-3bitA:
undetectable		 2g6kA-3bitA:
23.60
2g6kB-3bitA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.48A 2g6kA-3bitA:
undetectable
2g6kB-3bitA:
undetectable		 2g6kA-3bitA:
23.60
2g6kB-3bitA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 2g6mA-3bitA:
undetectable
2g6mB-3bitA:
undetectable		 2g6mA-3bitA:
23.60
2g6mB-3bitA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GL0_D_ADND904_1
(CONSERVED
HYPOTHETICAL PROTEIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 12 HIS A  52
PHE A  60
SER A  39
ASN A  53
THR A  49
 None
 1.36A 2gl0D-3bitA:
0.7
2gl0E-3bitA:
undetectable		 2gl0D-3bitA:
18.26
2gl0E-3bitA:
18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 2hx4A-3bitA:
undetectable
2hx4B-3bitA:
undetectable		 2hx4A-3bitA:
23.51
2hx4B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 225
LEU A 231
GLY A 190
SER A 188
ILE A 292
 None
 1.17A 2ogyA-3bitA:
undetectable		 2ogyA-3bitA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 225
LEU A 231
GLY A 190
SER A 188
ILE A 292
 None
 1.18A 2ogyB-3bitA:
undetectable		 2ogyB-3bitA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A600_1
(ORF12)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 11 SER A 187
THR A 419
SER A 299
TYR A 257
GLY A 190
 None
 1.42A 2xf3A-3bitA:
undetectable		 2xf3A-3bitA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_B_J01B600_1
(ORF12)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 11 SER A 187
THR A 419
SER A 299
TYR A 257
GLY A 190
 None
 1.44A 2xf3B-3bitA:
undetectable		 2xf3B-3bitA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_A_J01A1437_1
(ORF12)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 11 SER A 187
THR A 419
SER A 299
TYR A 257
GLY A 190
 None
 1.46A 2xh9A-3bitA:
1.4		 2xh9A-3bitA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XH9_B_J01B1437_1
(ORF12)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 10 SER A 187
THR A 419
SER A 299
TYR A 257
GLY A 190
 None
 1.43A 2xh9B-3bitA:
undetectable		 2xh9B-3bitA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 267
THR A 302
LEU A 198
ILE A 261
SER A 263
 None
 1.38A 2xrlA-3bitA:
undetectable		 2xrlA-3bitA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XYT_H_TC9H1206_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 THR A 302
GLN A 262
ILE A 260
SER A 397
 None
 1.17A 2xytI-3bitA:
undetectable		 2xytI-3bitA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YCJ_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 225
LEU A 231
GLY A 190
SER A 188
ILE A 292
 None
 1.29A 2ycjA-3bitA:
undetectable		 2ycjA-3bitA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA1_0
(FERROCHELATASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 11 LEU A  32
PHE A  34
ILE A  15
SER A  28
VAL A 172
 None
 1.34A 3aqiA-3bitA:
2.5		 3aqiA-3bitA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 3b3mA-3bitA:
undetectable
3b3mB-3bitA:
undetectable		 3b3mA-3bitA:
23.51
3b3mB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 3b3nA-3bitA:
1.6
3b3nB-3bitA:
1.3		 3b3nA-3bitA:
23.51
3b3nB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 3fc5A-3bitA:
undetectable
3fc5B-3bitA:
undetectable		 3fc5A-3bitA:
23.51
3fc5B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 3fc5A-3bitA:
undetectable
3fc5B-3bitA:
undetectable		 3fc5A-3bitA:
23.51
3fc5B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.48A 3hsnA-3bitA:
undetectable
3hsnB-3bitA:
undetectable		 3hsnA-3bitA:
23.51
3hsnB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 3hsoA-3bitA:
undetectable
3hsoB-3bitA:
undetectable		 3hsoA-3bitA:
23.51
3hsoB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 3hsoA-3bitA:
undetectable
3hsoB-3bitA:
undetectable		 3hsoA-3bitA:
23.51
3hsoB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.47A 3hspA-3bitA:
undetectable
3hspB-3bitA:
undetectable		 3hspA-3bitA:
23.51
3hspB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_A_SAMA301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 12 TRP A 151
PHE A 160
GLY A 132
ASP A 137
THR A  48
 None
 1.13A 3iv6A-3bitA:
undetectable		 3iv6A-3bitA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 3jt4A-3bitA:
undetectable
3jt4B-3bitA:
undetectable		 3jt4A-3bitA:
23.51
3jt4B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.48A 3jt5A-3bitA:
undetectable
3jt5B-3bitA:
undetectable		 3jt5A-3bitA:
23.51
3jt5B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.47A 3jt6A-3bitA:
undetectable
3jt6B-3bitA:
undetectable		 3jt6A-3bitA:
23.51
3jt6B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.48A 3jt9A-3bitA:
undetectable
3jt9B-3bitA:
undetectable		 3jt9A-3bitA:
23.51
3jt9B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.45A 3jtaA-3bitA:
undetectable
3jtaB-3bitA:
undetectable		 3jtaA-3bitA:
23.51
3jtaB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_A_AC2A301_1
(DEOXYCYTIDINE KINASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 9 ILE A 422
GLU A 174
ARG A 386
PHE A 394
LEU A 332
 None
 1.45A 3mjrA-3bitA:
undetectable		 3mjrA-3bitA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 3n5vA-3bitA:
undetectable
3n5vB-3bitA:
undetectable		 3n5vA-3bitA:
23.51
3n5vB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 3nlnA-3bitA:
undetectable
3nlnB-3bitA:
undetectable		 3nlnA-3bitA:
23.51
3nlnB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.48A 3nloA-3bitA:
undetectable
3nloB-3bitA:
1.3		 3nloA-3bitA:
23.51
3nloB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 3nloA-3bitA:
undetectable
3nloB-3bitA:
1.3		 3nloA-3bitA:
23.51
3nloB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 3nlwA-3bitA:
undetectable
3nlwB-3bitA:
undetectable		 3nlwA-3bitA:
23.51
3nlwB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 3nnzA-3bitA:
undetectable
3nnzB-3bitA:
undetectable		 3nnzA-3bitA:
23.51
3nnzB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PEO_F_CU9F301_2
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 THR A 302
GLN A 262
ILE A 260
SER A 397
 None
 1.00A 3peoG-3bitA:
undetectable		 3peoG-3bitA:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 3pnfA-3bitA:
undetectable
3pnfB-3bitA:
undetectable		 3pnfA-3bitA:
23.51
3pnfB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.48A 3q9aA-3bitA:
undetectable
3q9aB-3bitA:
undetectable		 3q9aA-3bitA:
23.51
3q9aB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 3rqjA-3bitA:
undetectable
3rqjB-3bitA:
undetectable		 3rqjA-3bitA:
23.51
3rqjB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 3svpA-3bitA:
undetectable
3svpB-3bitA:
undetectable		 3svpA-3bitA:
23.51
3svpB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 3tymA-3bitA:
undetectable
3tymB-3bitA:
undetectable		 3tymA-3bitA:
23.51
3tymB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 3tymA-3bitA:
undetectable
3tymB-3bitA:
undetectable		 3tymA-3bitA:
23.51
3tymB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 3tynA-3bitA:
undetectable
3tynB-3bitA:
undetectable		 3tynA-3bitA:
23.51
3tynB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 3tyoA-3bitA:
undetectable
3tyoB-3bitA:
1.3		 3tyoA-3bitA:
23.51
3tyoB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 3ufoA-3bitA:
undetectable
3ufoB-3bitA:
undetectable		 3ufoA-3bitA:
23.51
3ufoB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 3ufpA-3bitA:
undetectable
3ufpB-3bitA:
undetectable		 3ufpA-3bitA:
23.51
3ufpB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 3uftA-3bitA:
undetectable
3uftB-3bitA:
undetectable		 3uftA-3bitA:
23.51
3uftB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA505_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		3 / 3 THR A  49
ASN A  53
GLU A  59
 None
 0.68A 3v4tA-3bitA:
undetectable
3v4tC-3bitA:
undetectable		 3v4tA-3bitA:
22.49
3v4tC-3bitA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1479_0
(MJ0495-LIKE PROTEIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 5 THR A  99
ILE A  98
LYS A  71
PHE A  11
 None
 1.33A 4ac9C-3bitA:
undetectable		 4ac9C-3bitA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1479_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 5 THR A  99
ILE A  98
LYS A  71
PHE A  11
 None
 1.35A 4acaC-3bitA:
undetectable		 4acaC-3bitA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 4c39A-3bitA:
undetectable
4c39B-3bitA:
undetectable		 4c39A-3bitA:
23.51
4c39B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.48A 4ctrA-3bitA:
undetectable
4ctrB-3bitA:
0.0		 4ctrA-3bitA:
23.51
4ctrB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 4cttA-3bitA:
undetectable
4cttB-3bitA:
undetectable		 4cttA-3bitA:
23.51
4cttB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 4d1nC-3bitA:
undetectable
4d1nD-3bitA:
undetectable		 4d1nC-3bitA:
21.79
4d1nD-3bitA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.48A 4d2yA-3bitA:
undetectable
4d2yB-3bitA:
undetectable		 4d2yA-3bitA:
23.51
4d2yB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 4d2yA-3bitA:
undetectable
4d2yB-3bitA:
undetectable		 4d2yA-3bitA:
23.51
4d2yB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.48A 4d2zA-3bitA:
undetectable
4d2zB-3bitA:
undetectable		 4d2zA-3bitA:
23.51
4d2zB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.48A 4d30A-3bitA:
undetectable
4d30B-3bitA:
undetectable		 4d30A-3bitA:
23.51
4d30B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.47A 4d30A-3bitA:
undetectable
4d30B-3bitA:
undetectable		 4d30A-3bitA:
23.51
4d30B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 4d31A-3bitA:
undetectable
4d31B-3bitA:
undetectable		 4d31A-3bitA:
23.51
4d31B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.48A 4d31A-3bitA:
undetectable
4d31B-3bitA:
undetectable		 4d31A-3bitA:
23.51
4d31B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.46A 4d32A-3bitA:
undetectable
4d32B-3bitA:
undetectable		 4d32A-3bitA:
23.51
4d32B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 4d3bA-3bitA:
undetectable
4d3bB-3bitA:
undetectable		 4d3bA-3bitA:
23.51
4d3bB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 254
LEU A 231
GLY A 190
SER A 188
ILE A 292
 None
 1.30A 4djeA-3bitA:
undetectable		 4djeA-3bitA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.48A 4fvwA-3bitA:
undetectable
4fvwB-3bitA:
undetectable		 4fvwA-3bitA:
23.51
4fvwB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 4fvzA-3bitA:
undetectable
4fvzB-3bitA:
undetectable		 4fvzA-3bitA:
23.51
4fvzB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 4fw0A-3bitA:
undetectable
4fw0B-3bitA:
undetectable		 4fw0A-3bitA:
23.51
4fw0B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 4gqeA-3bitA:
undetectable
4gqeB-3bitA:
undetectable		 4gqeA-3bitA:
23.51
4gqeB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 4jsfA-3bitA:
undetectable
4jsfB-3bitA:
undetectable		 4jsfA-3bitA:
23.51
4jsfB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 4jsgA-3bitA:
undetectable
4jsgB-3bitA:
undetectable		 4jsgA-3bitA:
22.95
4jsgB-3bitA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.47A 4jshA-3bitA:
undetectable
4jshB-3bitA:
1.4		 4jshA-3bitA:
23.51
4jshB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 4jsiA-3bitA:
undetectable
4jsiB-3bitA:
undetectable		 4jsiA-3bitA:
23.51
4jsiB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 4k5eA-3bitA:
undetectable
4k5eB-3bitA:
undetectable		 4k5eA-3bitA:
22.95
4k5eB-3bitA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 4k5gA-3bitA:
undetectable
4k5gB-3bitA:
undetectable		 4k5gA-3bitA:
23.51
4k5gB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.47A 4uchA-3bitA:
undetectable
4uchB-3bitA:
undetectable		 4uchA-3bitA:
22.59
4uchB-3bitA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 8 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.46A 4uchA-3bitA:
undetectable
4uchB-3bitA:
undetectable		 4uchA-3bitA:
22.59
4uchB-3bitA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 4ugzA-3bitA:
undetectable
4ugzB-3bitA:
undetectable		 4ugzA-3bitA:
23.51
4ugzB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.48A 4uh1A-3bitA:
undetectable
4uh1B-3bitA:
undetectable		 4uh1A-3bitA:
23.51
4uh1B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 4uh4A-3bitA:
undetectable
4uh4B-3bitA:
undetectable		 4uh4A-3bitA:
23.51
4uh4B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 4uh5A-3bitA:
undetectable
4uh5B-3bitA:
undetectable		 4uh5A-3bitA:
22.64
4uh5B-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 4uh5A-3bitA:
undetectable
4uh5B-3bitA:
undetectable		 4uh5A-3bitA:
22.64
4uh5B-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 4v3uA-3bitA:
1.5
4v3uB-3bitA:
undetectable		 4v3uA-3bitA:
21.79
4v3uB-3bitA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.47A 4v3uC-3bitA:
undetectable
4v3uD-3bitA:
undetectable		 4v3uC-3bitA:
21.79
4v3uD-3bitA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3W_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.44A 4v3wA-3bitA:
undetectable
4v3wB-3bitA:
undetectable		 4v3wA-3bitA:
23.51
4v3wB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.46A 4v3yA-3bitA:
undetectable
4v3yB-3bitA:
undetectable		 4v3yA-3bitA:
23.51
4v3yB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.47A 4v3zA-3bitA:
undetectable
4v3zB-3bitA:
undetectable		 4v3zA-3bitA:
23.51
4v3zB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.46A 4v3zA-3bitA:
undetectable
4v3zB-3bitA:
undetectable		 4v3zA-3bitA:
23.51
4v3zB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.48A 5ad4A-3bitA:
undetectable
5ad4B-3bitA:
undetectable		 5ad4A-3bitA:
23.51
5ad4B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 5ad5A-3bitA:
undetectable
5ad5B-3bitA:
undetectable		 5ad5A-3bitA:
23.51
5ad5B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.48A 5ad6A-3bitA:
undetectable
5ad6B-3bitA:
undetectable		 5ad6A-3bitA:
23.51
5ad6B-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.46A 5adbA-3bitA:
0.1
5adbB-3bitA:
0.3		 5adbA-3bitA:
23.51
5adbB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.47A 5adcA-3bitA:
undetectable
5adcB-3bitA:
undetectable		 5adcA-3bitA:
23.51
5adcB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 5adeA-3bitA:
undetectable
5adeB-3bitA:
undetectable		 5adeA-3bitA:
23.92
5adeB-3bitA:
23.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 5agkA-3bitA:
undetectable
5agkB-3bitA:
undetectable		 5agkA-3bitA:
23.51
5agkB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.48A 5agkA-3bitA:
undetectable
5agkB-3bitA:
undetectable		 5agkA-3bitA:
23.51
5agkB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.47A 5agnA-3bitA:
undetectable
5agnB-3bitA:
undetectable		 5agnA-3bitA:
23.51
5agnB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 5fvpA-3bitA:
undetectable
5fvpB-3bitA:
undetectable		 5fvpA-3bitA:
23.51
5fvpB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.48A 5fvpA-3bitA:
undetectable
5fvpB-3bitA:
undetectable		 5fvpA-3bitA:
23.51
5fvpB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 5fvsA-3bitA:
undetectable
5fvsB-3bitA:
undetectable		 5fvsA-3bitA:
23.51
5fvsB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 5fvuA-3bitA:
1.4
5fvuB-3bitA:
undetectable		 5fvuA-3bitA:
22.64
5fvuB-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.43A 5fvuA-3bitA:
1.4
5fvuB-3bitA:
undetectable		 5fvuA-3bitA:
22.64
5fvuB-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.48A 5fvvA-3bitA:
undetectable
5fvvB-3bitA:
undetectable		 5fvvA-3bitA:
22.64
5fvvB-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.46A 5fvvA-3bitA:
undetectable
5fvvB-3bitA:
undetectable		 5fvvA-3bitA:
22.64
5fvvB-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 6 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.47A 5fvxA-3bitA:
0.8
5fvxB-3bitA:
0.6		 5fvxA-3bitA:
22.64
5fvxB-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 5g0nA-3bitA:
undetectable
5g0nB-3bitA:
undetectable		 5g0nA-3bitA:
23.71
5g0nB-3bitA:
23.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 LEU A  18
TYR A  22
THR A 130
LEU A  51
 None
 1.13A 5jq7B-3bitA:
undetectable		 5jq7B-3bitA:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 10 TYR A  19
ILE A  15
ILE A  65
ILE A  73
ILE A  74
 None
 1.09A 5murE-3bitA:
undetectable		 5murE-3bitA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_1
(METHYLTRANSFERASE)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 143
SER A  38
GLU A 146
ASN A 106
 None
 1.07A 5n5dB-3bitA:
undetectable		 5n5dB-3bitA:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		3 / 3 CYH A 285
MET A 313
ASN A 316
 None
 1.23A 5qh8A-3bitA:
undetectable		 5qh8A-3bitA:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.48A 5untA-3bitA:
undetectable
5untB-3bitA:
undetectable		 5untA-3bitA:
23.51
5untB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.47A 5uo4A-3bitA:
undetectable
5uo4B-3bitA:
undetectable		 5uo4A-3bitA:
22.64
5uo4B-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 5uo4A-3bitA:
undetectable
5uo4B-3bitA:
undetectable		 5uo4A-3bitA:
22.64
5uo4B-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 5vujA-3bitA:
undetectable
5vujB-3bitA:
undetectable		 5vujA-3bitA:
23.51
5vujB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.48A 5vujA-3bitA:
undetectable
5vujB-3bitA:
undetectable		 5vujA-3bitA:
23.51
5vujB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 5vukA-3bitA:
0.6
5vukB-3bitA:
undetectable		 5vukA-3bitA:
23.51
5vukB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 5vunA-3bitA:
undetectable
5vunB-3bitA:
undetectable		 5vunA-3bitA:
23.51
5vunB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.49A 5vurA-3bitA:
undetectable
5vurB-3bitA:
undetectable		 5vurA-3bitA:
23.51
5vurB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 5vutA-3bitA:
undetectable
5vutB-3bitA:
undetectable		 5vutA-3bitA:
23.51
5vutB-3bitA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 5vuwA-3bitA:
undetectable
5vuwB-3bitA:
undetectable		 5vuwA-3bitA:
22.64
5vuwB-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 5vuyA-3bitA:
undetectable
5vuyB-3bitA:
undetectable		 5vuyA-3bitA:
22.64
5vuyB-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 5vv2A-3bitA:
undetectable
5vv2B-3bitA:
undetectable		 5vv2A-3bitA:
22.64
5vv2B-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 5vv5A-3bitA:
undetectable
5vv5B-3bitA:
undetectable		 5vv5A-3bitA:
22.64
5vv5B-3bitA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		5 / 12 GLY A 291
LEU A 252
ASN A 295
ASP A 251
PHE A 250
 None
 1.26A 5yn6A-3bitA:
undetectable		 5yn6A-3bitA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 6auqA-3bitA:
undetectable
6auqB-3bitA:
undetectable		 6auqA-3bitA:
11.11
6auqB-3bitA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 6ausA-3bitA:
undetectable
6ausB-3bitA:
undetectable		 6ausA-3bitA:
11.11
6ausB-3bitA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 6auyA-3bitA:
1.4
6auyB-3bitA:
undetectable		 6auyA-3bitA:
10.43
6auyB-3bitA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 6auzA-3bitA:
undetectable
6auzB-3bitA:
undetectable		 6auzA-3bitA:
10.43
6auzB-3bitA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.46A 6av1A-3bitA:
undetectable
6av1B-3bitA:
undetectable		 6av1A-3bitA:
10.43
6av1B-3bitA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.50A 6av2A-3bitA:
undetectable
6av2B-3bitA:
undetectable		 6av2A-3bitA:
10.43
6av2B-3bitA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 ARG A 105
VAL A  35
TRP A 147
PHE A 117
 None
 1.49A 6av3A-3bitA:
undetectable
6av3B-3bitA:
undetectable		 6av3A-3bitA:
10.43
6av3B-3bitA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bit FACT COMPLEX SUBUNIT
SPT16
(Saccharomyces
cerevisiae) 		4 / 7 TRP A 147
PHE A 117
ARG A 105
VAL A  35
 None
 1.50A 6av3A-3bitA:
undetectable
6av3B-3bitA:
undetectable		 6av3A-3bitA:
10.43
6av3B-3bitA:
10.43