SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bj5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3bj5 PROTEIN
DISULFIDE-ISOMERASE
(Homo
sapiens) 		5 / 12 THR A 302
PHE A 232
PHE A 288
PHE A 243
ALA A 272
 None
 1.29A 1q23A-3bj5A:
undetectable
1q23B-3bj5A:
undetectable		 1q23A-3bj5A:
19.63
1q23B-3bj5A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_G_FUAG708_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3bj5 PROTEIN
DISULFIDE-ISOMERASE
(Homo
sapiens) 		5 / 11 THR A 302
PHE A 232
PHE A 288
PHE A 325
PHE A 243
 None
 1.46A 1q23G-3bj5A:
undetectable		 1q23G-3bj5A:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 3bj5 PROTEIN
DISULFIDE-ISOMERASE
(Homo
sapiens) 		5 / 12 LEU A 255
ILE A 269
PRO A 296
VAL A 248
VAL A 298
 None
 1.33A 3aqiB-3bj5A:
undetectable		 3aqiB-3bj5A:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 3bj5 PROTEIN
DISULFIDE-ISOMERASE
(Homo
sapiens) 		5 / 12 ALA A 272
ILE A 301
PHE A 232
GLY A 234
ILE A 221
 None
 1.05A 5m24A-3bj5A:
undetectable		 5m24A-3bj5A:
22.40