SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bjb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 3bjb PROBABLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 5 ARG A  49
ALA A  33
LYS A  36
GLU A  35
 None
 1.07A 1e7cA-3bjbA:
3.2		 1e7cA-3bjbA:
15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 3bjb PROBABLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 ALA A  50
GLY A  55
THR A  56
LEU A  32
LEU A  67
 None
SO4  A 319 (-3.2A)
SO4  A 320 (-2.8A)
None
None
 1.29A 1jipA-3bjbA:
undetectable		 1jipA-3bjbA:
22.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QAB_F_RTLF2_0
(PROTEIN (RETINOL
BINDING PROTEIN))		 3bjb PROBABLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 ALA A  53
ALA A  47
GLY A  55
TYR A  58
LEU A  67
 SO4  A 320 (-3.7A)
None
SO4  A 319 (-3.2A)
None
None
 1.16A 1qabF-3bjbA:
undetectable		 1qabF-3bjbA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XP0_A_VDNA201_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 3bjb PROBABLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 10 LEU A  26
ALA A  28
VAL A  52
ALA A  53
PHE A  61
 None
None
SO4  A 320 ( 4.0A)
SO4  A 320 (-3.7A)
None
 1.02A 1xp0A-3bjbA:
undetectable		 1xp0A-3bjbA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3bjb PROBABLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 MET A  72
ILE A 189
LEU A 164
GLY A 170
ILE A 172
 None
 1.26A 2e7fA-3bjbA:
undetectable		 2e7fA-3bjbA:
23.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 3bjb PROBABLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 MET A  72
ILE A 189
LEU A 164
GLY A 170
ILE A 172
 None
 1.30A 2ogyA-3bjbA:
undetectable		 2ogyA-3bjbA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3bjb PROBABLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 6 GLN A  42
PHE A  68
LEU A  67
PHE A  61
 None
 1.11A 3ablP-3bjbA:
3.2
3ablW-3bjbA:
undetectable		 3ablP-3bjbA:
20.75
3ablW-3bjbA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3bjb PROBABLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 ASP A 194
LEU A 145
ASP A 157
ARG A 190
LEU A 101
 None
 1.32A 5syfB-3bjbA:
undetectable		 5syfB-3bjbA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3bjb PROBABLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 5 LEU A 196
LEU A 163
MET A 144
TYR A  98
 None
 1.23A 5uc3A-3bjbA:
undetectable		 5uc3A-3bjbA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 3bjb PROBABLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		5 / 12 ILE A 119
VAL A 165
LEU A 176
THR A 105
LEU A 109
 None
 1.15A 6b54A-3bjbA:
undetectable		 6b54A-3bjbA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_D_EY4D500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3bjb PROBABLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 7 ILE A 119
GLN A 120
ALA A  33
THR A  34
 None
 0.94A 6cduC-3bjbA:
3.5
6cduD-3bjbA:
3.4		 6cduC-3bjbA:
20.87
6cduD-3bjbA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3bjb PROBABLE
TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY PROTEIN
(Rhodococcus
jostii) 		4 / 7 ALA A  33
THR A  34
ILE A 119
GLN A 120
 None
 0.86A 6cduF-3bjbA:
3.6
6cduJ-3bjbA:
3.3		 6cduF-3bjbA:
20.87
6cduJ-3bjbA:
20.87