SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bjl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 5 LYS A  46
ALA A  44
LEU A  40
SER A  41
 None
 0.89A 1tt6B-3bjlA:
2.7		 1tt6B-3bjlA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TZ8_C_DESC129_1
(TRANSTHYRETIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 6 LYS A  46
ALA A  44
LEU A  40
SER A  41
 None
 0.85A 1tz8C-3bjlA:
3.7
1tz8D-3bjlA:
undetectable		 1tz8C-3bjlA:
22.79
1tz8D-3bjlA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.20A 1zzrA-3bjlA:
undetectable
1zzrB-3bjlA:
undetectable		 1zzrA-3bjlA:
21.09
1zzrB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.23A 1zzrA-3bjlA:
undetectable
1zzrB-3bjlA:
undetectable		 1zzrA-3bjlA:
21.09
1zzrB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.17A 1zzuA-3bjlA:
undetectable
1zzuB-3bjlA:
undetectable		 1zzuA-3bjlA:
21.09
1zzuB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.17A 1zzuA-3bjlA:
undetectable
1zzuB-3bjlA:
undetectable		 1zzuA-3bjlA:
21.09
1zzuB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 SER A  66
ALA A  72
SER A  73
SER A  68
 None
 1.02A 2i91B-3bjlA:
undetectable		 2i91B-3bjlA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		3 / 3 LYS A 167
TYR A 176
PRO A 168
 None
 1.49A 2j9cC-3bjlA:
undetectable		 2j9cC-3bjlA:
17.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OLD_B_IPHB2001_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 TYR A  37
HIS A  39
PRO A  45
TYR A  88
 None
 0.51A 2oldA-3bjlA:
18.9
2oldB-3bjlA:
18.9		 2oldA-3bjlA:
77.88
2oldB-3bjlA:
77.88
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 TYR A  37
HIS A  39
PRO A  45
TYR A  88
 None
 0.60A 2ombC-3bjlA:
24.4
2ombD-3bjlA:
20.3		 2ombC-3bjlA:
77.88
2ombD-3bjlA:
77.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		5 / 12 LEU A  74
ILE A  20
VAL A  59
THR A  85
ARG A  62
 None
 1.27A 2qo4A-3bjlA:
undetectable		 2qo4A-3bjlA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO6_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		5 / 12 LEU A  74
ILE A  20
VAL A  59
THR A  85
ARG A  62
 None
 1.28A 2qo6A-3bjlA:
undetectable		 2qo6A-3bjlA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_A_1FLA502_1
(TRANSTHYRETIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 LYS A  46
ALA A  44
LEU A  40
SER A  41
 None
 0.95A 3d2tA-3bjlA:
3.6		 3d2tA-3bjlA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D2T_B_1FLB500_1
(TRANSTHYRETIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 6 LYS A  46
ALA A  44
LEU A  40
SER A  41
 None
 0.94A 3d2tB-3bjlA:
3.8		 3d2tB-3bjlA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.23A 3dqrA-3bjlA:
undetectable
3dqrB-3bjlA:
undetectable		 3dqrA-3bjlA:
21.09
3dqrB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.26A 3dqrA-3bjlA:
undetectable
3dqrB-3bjlA:
undetectable		 3dqrA-3bjlA:
21.09
3dqrB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.14A 3jx2A-3bjlA:
undetectable
3jx2B-3bjlA:
undetectable		 3jx2A-3bjlA:
21.09
3jx2B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.19A 3jx2A-3bjlA:
undetectable
3jx2B-3bjlA:
undetectable		 3jx2A-3bjlA:
21.09
3jx2B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.18A 3jx3A-3bjlA:
undetectable
3jx3B-3bjlA:
undetectable		 3jx3A-3bjlA:
21.09
3jx3B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.17A 3jx3A-3bjlA:
undetectable
3jx3B-3bjlA:
undetectable		 3jx3A-3bjlA:
21.09
3jx3B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.23A 3jx4A-3bjlA:
undetectable
3jx4B-3bjlA:
undetectable		 3jx4A-3bjlA:
21.09
3jx4B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.19A 3jx5A-3bjlA:
undetectable
3jx5B-3bjlA:
undetectable		 3jx5A-3bjlA:
21.09
3jx5B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.20A 3jx5A-3bjlA:
undetectable
3jx5B-3bjlA:
undetectable		 3jx5A-3bjlA:
21.09
3jx5B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.08A 3jx6A-3bjlA:
undetectable
3jx6B-3bjlA:
undetectable		 3jx6A-3bjlA:
21.09
3jx6B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX6_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.14A 3jx6A-3bjlA:
undetectable
3jx6B-3bjlA:
undetectable		 3jx6A-3bjlA:
21.09
3jx6B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.11A 3nljA-3bjlA:
undetectable
3nljB-3bjlA:
undetectable		 3nljA-3bjlA:
21.09
3nljB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLJ_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.17A 3nljA-3bjlA:
undetectable
3nljB-3bjlA:
undetectable		 3nljA-3bjlA:
21.09
3nljB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.16A 3nlpA-3bjlA:
undetectable
3nlpB-3bjlA:
undetectable		 3nlpA-3bjlA:
21.09
3nlpB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.20A 3nlpA-3bjlA:
undetectable
3nlpB-3bjlA:
undetectable		 3nlpA-3bjlA:
21.09
3nlpB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 8 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.15A 3nlqA-3bjlA:
undetectable
3nlqB-3bjlA:
undetectable		 3nlqA-3bjlA:
21.09
3nlqB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.23A 3nlqA-3bjlA:
undetectable
3nlqB-3bjlA:
undetectable		 3nlqA-3bjlA:
21.09
3nlqB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.14A 3nlrA-3bjlA:
undetectable
3nlrB-3bjlA:
undetectable		 3nlrA-3bjlA:
21.09
3nlrB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.18A 4cx3A-3bjlA:
undetectable
4cx3B-3bjlA:
undetectable		 4cx3A-3bjlA:
21.09
4cx3B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.18A 4cx3A-3bjlA:
undetectable
4cx3B-3bjlA:
undetectable		 4cx3A-3bjlA:
21.09
4cx3B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.21A 4cx4A-3bjlA:
undetectable
4cx4B-3bjlA:
undetectable		 4cx4A-3bjlA:
21.09
4cx4B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.18A 4cx4A-3bjlA:
undetectable
4cx4B-3bjlA:
undetectable		 4cx4A-3bjlA:
21.09
4cx4B-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 6 LYS A  46
ALA A  44
LEU A  40
SER A  41
 None
 0.89A 4i89A-3bjlA:
3.6		 4i89A-3bjlA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0U_A_ADNA501_1
(AURORA KINASE A)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		5 / 6 VAL A 159
ALA A 154
LEU A 136
THR A 185
LEU A 184
 None
 1.45A 4o0uA-3bjlA:
undetectable		 4o0uA-3bjlA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 6 LYS A  46
ALA A  44
LEU A  40
SER A  41
 None
 0.78A 4pwjA-3bjlA:
3.7		 4pwjA-3bjlA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_B_30ZB201_1
(TRANSTHYRETIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 LYS A  46
ALA A  44
LEU A  40
SER A  41
 None
 0.74A 4pwjB-3bjlA:
3.7		 4pwjB-3bjlA:
22.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.19A 5addA-3bjlA:
undetectable
5addB-3bjlA:
undetectable		 5addA-3bjlA:
21.09
5addB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 6 LYS A  46
ALA A  44
LEU A  40
SER A  41
 None
 0.81A 5bojA-3bjlA:
undetectable		 5bojA-3bjlA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_B_4TXB201_1
(TRANSTHYRETIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 LYS A  46
ALA A  44
LEU A  40
SER A  41
 None
 0.80A 5bojB-3bjlA:
undetectable		 5bojB-3bjlA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 VAL A 109
ARG A  62
VAL A  18
GLU A  84
 None
 1.19A 5g0pA-3bjlA:
undetectable
5g0pB-3bjlA:
undetectable		 5g0pA-3bjlA:
21.09
5g0pB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0P_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 7 GLU A  84
VAL A 109
ARG A  62
VAL A  18
 None
 1.20A 5g0pA-3bjlA:
undetectable
5g0pB-3bjlA:
undetectable		 5g0pA-3bjlA:
21.09
5g0pB-3bjlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 3bjl LOC - LAMBDA 1 TYPE
LIGHT-CHAIN DIMER
(Homo
sapiens) 		4 / 6 LYS A  46
ALA A  44
LEU A  40
SER A  41
 None
 0.94A 5l4iA-3bjlA:
3.4		 5l4iA-3bjlA:
22.79