SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bjz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3bjz PHOSPHOHEPTOSE
ISOMERASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 153
SER A 154
ALA A 143
GLY A 122
GLY A 149
 None
 1.09A 2igtA-3bjzA:
2.9		 2igtA-3bjzA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3bjz PHOSPHOHEPTOSE
ISOMERASE
(Pseudomonas
aeruginosa) 		5 / 12 ALA A 153
SER A 154
ALA A 143
GLY A 122
GLY A 149
 None
 1.08A 2igtB-3bjzA:
3.2		 2igtB-3bjzA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9M_A_SALA1200_1
(SERUM ALBUMIN)		 3bjz PHOSPHOHEPTOSE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 5 ILE A 173
HIS A 177
ARG A 164
GLY A 122
 None
 1.06A 3b9mA-3bjzA:
undetectable		 3b9mA-3bjzA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 3bjz PHOSPHOHEPTOSE
ISOMERASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  25
LEU A 184
ALA A 180
ALA A 143
VAL A 161
 None
 1.27A 3e22B-3bjzA:
4.3		 3e22B-3bjzA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 3bjz PHOSPHOHEPTOSE
ISOMERASE
(Pseudomonas
aeruginosa) 		5 / 11 LEU A  25
LEU A 184
ALA A 180
ALA A 143
VAL A 161
 None
 1.28A 3e22D-3bjzA:
4.3		 3e22D-3bjzA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 3bjz PHOSPHOHEPTOSE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 5 LYS A  45
PRO A  77
SER A  75
SER A  62
 None
 1.35A 3ijxH-3bjzA:
undetectable		 3ijxH-3bjzA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 3bjz PHOSPHOHEPTOSE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 5 LYS A  45
PRO A  77
SER A  75
LEU A  47
 None
 1.13A 3iluH-3bjzA:
undetectable		 3iluH-3bjzA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 3bjz PHOSPHOHEPTOSE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 5 LYS A  45
PRO A  77
SER A  75
SER A  62
 None
 1.36A 3iluH-3bjzA:
undetectable		 3iluH-3bjzA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MSS_C_STIC1_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3bjz PHOSPHOHEPTOSE
ISOMERASE
(Pseudomonas
aeruginosa) 		4 / 6 VAL A  37
VAL A 142
ILE A  46
ARG A 190
 None
 1.12A 3mssC-3bjzA:
undetectable		 3mssC-3bjzA:
22.19