SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bk5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 3bk5 PUTATIVE OUTER
MEMBRANE
LIPOPROTEIN-SORTING
PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 PHE A 116
LEU A   4
ALA A   7
PRO A 164
VAL A 167
 None
 1.22A 3cwkA-3bk5A:
3.0		 3cwkA-3bk5A:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 3bk5 PUTATIVE OUTER
MEMBRANE
LIPOPROTEIN-SORTING
PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 THR A 209
SER A 106
PHE A 169
 None
 0.55A 3d4sA-3bk5A:
undetectable		 3d4sA-3bk5A:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_2
(PROTEASE)		 3bk5 PUTATIVE OUTER
MEMBRANE
LIPOPROTEIN-SORTING
PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 ARG A 194
LEU A 216
THR A 220
 None
 0.86A 3oxcA-3bk5A:
undetectable		 3oxcA-3bk5A:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 3bk5 PUTATIVE OUTER
MEMBRANE
LIPOPROTEIN-SORTING
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 5 GLY A 174
ASP A 171
ARG A 172
GLN A 141
 None
 1.23A 3qx3A-3bk5A:
undetectable		 3qx3A-3bk5A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)		 3bk5 PUTATIVE OUTER
MEMBRANE
LIPOPROTEIN-SORTING
PROTEIN
(Vibrio
parahaemolyticus) 		4 / 5 GLY A 174
ASP A 171
ARG A 172
GLN A 141
 None
 1.31A 3qx3B-3bk5A:
undetectable		 3qx3B-3bk5A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_2
(NEURAMINIDASE)		 3bk5 PUTATIVE OUTER
MEMBRANE
LIPOPROTEIN-SORTING
PROTEIN
(Vibrio
parahaemolyticus) 		3 / 3 ARG A 163
ARG A  13
TRP A 193
 None
 1.36A 4cpzG-3bk5A:
undetectable		 4cpzG-3bk5A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3bk5 PUTATIVE OUTER
MEMBRANE
LIPOPROTEIN-SORTING
PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 SER A 106
LEU A 211
PHE A  58
LEU A  83
TYR A 110
 None
 1.36A 5y2oA-3bk5A:
undetectable		 5y2oA-3bk5A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2O_A_8N6A501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3bk5 PUTATIVE OUTER
MEMBRANE
LIPOPROTEIN-SORTING
PROTEIN
(Vibrio
parahaemolyticus) 		5 / 12 SER A 106
LEU A 211
PHE A  58
MET A  40
LEU A  83
 None
 1.06A 5y2oA-3bk5A:
undetectable		 5y2oA-3bk5A:
18.93