SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bk6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_A_IMNA379_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	3bk6	PH STOMATIN (Pyrococcus horikoshii)	5 / 12	VAL A 72 SER A 113 ILE A 115 VAL A 161 LEU A 70	None	1.32A	1z9hA-3bk6A: undetectable	1z9hA-3bk6A: 21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_B_IMNB381_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	3bk6	PH STOMATIN (Pyrococcus horikoshii)	5 / 12	VAL A 72 SER A 113 ILE A 115 VAL A 161 LEU A 70	None	1.32A	1z9hB-3bk6A: undetectable	1z9hB-3bk6A: 21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Z9H_C_IMNC379_1 (MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2)	3bk6	PH STOMATIN (Pyrococcus horikoshii)	5 / 12	VAL A 72 SER A 113 ILE A 115 VAL A 161 LEU A 70	None	1.32A	1z9hC-3bk6A: undetectable	1z9hC-3bk6A: 21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOP_A_C2FA3001_1 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bk6	PH STOMATIN (Pyrococcus horikoshii)	3 / 3	ASP A 165 ASN A 88 ASP A 71	None	0.77A	5vopA-3bk6A: undetectable	5vopA-3bk6A: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOP_B_C2FB3001_1 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bk6	PH STOMATIN (Pyrococcus horikoshii)	3 / 3	ASP A 165 ASN A 88 ASP A 71	None	0.87A	5vopB-3bk6A: undetectable	5vopB-3bk6A: 21.52

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Z9H_A_IMNA379_1","MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2","3bk6","PH STOMATIN","Pyrococcus horikoshii",5,"VAL A  72;SER A 113;ILE A 115;VAL A 161;LEU A  70","None","1.32A","1z9hA-3bk6A:undetectable","1z9hA-3bk6A:21.89"],["1Z9H_B_IMNB381_1","MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2","3bk6","PH STOMATIN","Pyrococcus horikoshii",5,"VAL A  72;SER A 113;ILE A 115;VAL A 161;LEU A  70","None","1.32A","1z9hB-3bk6A:undetectable","1z9hB-3bk6A:21.89"],["1Z9H_C_IMNC379_1","MEMBRANE-ASSOCIATED PROSTAGLANDIN E SYNTHASE-2","3bk6","PH STOMATIN","Pyrococcus horikoshii",5,"VAL A  72;SER A 113;ILE A 115;VAL A 161;LEU A  70","None","1.32A","1z9hC-3bk6A:undetectable","1z9hC-3bk6A:21.89"],["5VOP_A_C2FA3001_1","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bk6","PH STOMATIN","Pyrococcus horikoshii",3,"ASP A 165;ASN A  88;ASP A  71","None","0.77A","5vopA-3bk6A:undetectable","5vopA-3bk6A:21.52"],["5VOP_B_C2FB3001_1","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bk6","PH STOMATIN","Pyrococcus horikoshii",3,"ASP A 165;ASN A  88;ASP A  71","None","0.87A","5vopB-3bk6A:undetectable","5vopB-3bk6A:21.52"]]