SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bkh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		5 / 12 LEU A 196
LEU A 211
ARG A 189
ILE A 182
GLY A 205
 None
 1.10A 1g50B-3bkhA:
undetectable		 1g50B-3bkhA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		5 / 11 LEU A 196
LEU A 211
ARG A 189
ILE A 182
GLY A 205
 None
 1.09A 1g50C-3bkhA:
undetectable		 1g50C-3bkhA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		4 / 8 THR A 194
ASP A 252
ASN A 249
LEU A 187
 None
 1.07A 1lhvA-3bkhA:
undetectable		 1lhvA-3bkhA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		4 / 5 ARG A 189
LEU A 198
ASP A 195
LEU A 183
 None
 1.23A 1n13B-3bkhA:
undetectable
1n13C-3bkhA:
undetectable		 1n13B-3bkhA:
17.54
1n13C-3bkhA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		4 / 7 VAL A 247
PHE A 223
HIS A 222
THR A 213
 None
 1.15A 2f78B-3bkhA:
undetectable		 2f78B-3bkhA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		4 / 6 PHE A 234
PRO A 241
LYS A 242
THR A 243
 None
 1.21A 2m2oB-3bkhA:
undetectable		 2m2oB-3bkhA:
6.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		4 / 7 PHE A 133
LEU A 109
ALA A 112
PHE A 118
 None
 0.97A 2vcvA-3bkhA:
undetectable		 2vcvA-3bkhA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		4 / 7 PHE A 133
LEU A 109
ALA A 112
PHE A 118
 None
 0.94A 2vcvL-3bkhA:
undetectable		 2vcvL-3bkhA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		5 / 12 ALA A 112
PHE A 133
ILE A  78
ALA A  90
VAL A  97
 None
 0.82A 4nkxB-3bkhA:
undetectable		 4nkxB-3bkhA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		3 / 3 ASN A  21
ASP A  31
GLY A  32
 None
 0.52A 5fctB-3bkhA:
undetectable		 5fctB-3bkhA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		3 / 3 ASP A 195
ASN A 249
GLN A 245
 None
 0.83A 5k7uA-3bkhA:
undetectable		 5k7uA-3bkhA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		4 / 7 THR A 221
LEU A 218
ILE A 244
THR A 243
 None
 0.93A 5zsfA-3bkhA:
undetectable
5zsfB-3bkhA:
undetectable		 5zsfA-3bkhA:
13.26
5zsfB-3bkhA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		3 / 3 GLN A 245
TYR A 248
ASN A 249
 None
 1.04A 6dwdC-3bkhA:
undetectable		 6dwdC-3bkhA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		4 / 4 HIS A  -3
LEU A 161
TYR A  75
GLY A 148
 None
 1.34A 6n91A-3bkhA:
undetectable		 6n91A-3bkhA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 3bkh LYTIC
TRANSGLYCOSYLASE
(Pseudomonas
virus
phiKZ) 		4 / 4 HIS A  -3
LEU A 161
TYR A  75
GLY A 148
 None
 1.34A 6n91B-3bkhA:
undetectable		 6n91B-3bkhA:
15.15