SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bkn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_A_DAHA208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3bkn BACTERIOFERRITIN
(Mycolicibacteriu
m
smegmatis) 		5 / 11 GLU A  51
HIS A  54
GLU A  94
ILE A 123
GLU A 127
 ZN  A 201 ( 2.4A)
ZN  A 201 (-3.1A)
ZN  A 202 (-2.2A)
None
ZN  A 201 ( 2.3A)
 0.80A 1rnrA-3bknA:
9.8		 1rnrA-3bknA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RNR_B_DAHB208_1
(RIBONUCLEOTIDE
REDUCTASE R1 PROTEIN)		 3bkn BACTERIOFERRITIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 GLU A  51
HIS A  54
GLU A  94
ILE A 123
GLU A 127
 ZN  A 201 ( 2.4A)
ZN  A 201 (-3.1A)
ZN  A 202 (-2.2A)
None
ZN  A 201 ( 2.3A)
 0.79A 1rnrB-3bknA:
9.8		 1rnrB-3bknA:
17.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_2
(THYROID HORMONE
RECEPTOR BETA-1)		 3bkn BACTERIOFERRITIN
(Mycolicibacteriu
m
smegmatis) 		4 / 5 ILE A  62
ARG A  73
LEU A  15
ASN A  12
 None
 1.18A 1y0xX-3bknA:
undetectable		 1y0xX-3bknA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KCX_A_CQLA1_0
(HYPOXIA-INDUCIBLE
FACTOR 1-ALPHA
INHIBITOR)		 3bkn BACTERIOFERRITIN
(Mycolicibacteriu
m
smegmatis) 		5 / 10 TYR A  71
LEU A  19
THR A  59
ILE A 123
ILE A  58
 None
 1.48A 3kcxA-3bknA:
undetectable		 3kcxA-3bknA:
18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP3_B_AICB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3bkn BACTERIOFERRITIN
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ALA A  46
ARG A  45
LYS A  30
 None
 0.90A 3kp3B-3bknA:
undetectable		 3kp3B-3bknA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 3bkn BACTERIOFERRITIN
(Mycolicibacteriu
m
smegmatis) 		4 / 7 PRO A  69
GLY A  67
ASP A  60
ARG A  61
 None
 0.76A 3ur0B-3bknA:
undetectable		 3ur0B-3bknA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 3bkn BACTERIOFERRITIN
(Mycolicibacteriu
m
smegmatis) 		5 / 12 HIS A  28
TRP A  35
LEU A  27
GLU A  85
ALA A  89
 None
 1.16A 4hfpD-3bknA:
undetectable		 4hfpD-3bknA:
24.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 3bkn BACTERIOFERRITIN
(Mycolicibacteriu
m
smegmatis) 		4 / 7 GLU A 127
HIS A  54
VAL A  97
GLU A  94
 ZN  A 201 ( 2.3A)
ZN  A 201 (-3.1A)
None
ZN  A 202 (-2.2A)
 0.96A 4hvrA-3bknA:
undetectable		 4hvrA-3bknA:
21.98