SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bkp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_E_REAE176_1
(RETINOL BINDING
PROTEIN)		 3bkp CYCLOPHILIN
(Toxoplasma
gondii) 		5 / 10 LEU A  26
ALA A 113
VAL A  24
LEU A  37
PHE A  63
 None
 1.27A 1rlbE-3bkpA:
undetectable		 1rlbE-3bkpA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 3bkp CYCLOPHILIN
(Toxoplasma
gondii) 		5 / 12 LEU A 166
LEU A 163
VAL A  35
LEU A  26
THR A  28
 None
 1.16A 2q7kA-3bkpA:
undetectable		 2q7kA-3bkpA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA300_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 3bkp CYCLOPHILIN
(Toxoplasma
gondii) 		4 / 6 TYR A  58
CYH A  53
VAL A  35
PHE A 138
 None
 1.32A 3ltwA-3bkpA:
undetectable		 3ltwA-3bkpA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CLT_A_ACRA1000_1
(1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME)		 3bkp CYCLOPHILIN
(Toxoplasma
gondii) 		5 / 10 PRO A 205
TYR A  57
GLY A  56
GLU A  55
ARG A 202
 None
GOL  A 304 ( 4.6A)
None
None
GOL  A 304 (-2.8A)
 1.30A 5cltA-3bkpA:
0.0		 5cltA-3bkpA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CLT_B_ACRB1000_1
(1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME)		 3bkp CYCLOPHILIN
(Toxoplasma
gondii) 		5 / 10 PRO A 205
TYR A  57
GLY A  56
GLU A  55
ARG A 202
 None
GOL  A 304 ( 4.6A)
None
None
GOL  A 304 (-2.8A)
 1.25A 5cltB-3bkpA:
0.4		 5cltB-3bkpA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CLT_C_ACRC1000_1
(1,4-ALPHA-GLUCAN-BRA
NCHING ENZYME)		 3bkp CYCLOPHILIN
(Toxoplasma
gondii) 		5 / 10 PRO A 205
TYR A  57
GLY A  56
GLU A  55
ARG A 202
 None
GOL  A 304 ( 4.6A)
None
None
GOL  A 304 (-2.8A)
 1.26A 5cltC-3bkpA:
0.0		 5cltC-3bkpA:
17.90