SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bl2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UW6_A_NCTA1208_1 (ACETYLCHOLINE-BINDIN G PROTEIN)	3bl2	V-BCL-2 (Murid gammaherpesvirus 4)	4 / 8	THR A 15 CYH A 99 LEU A 115 MET A 119	None	1.04A	1uw6A-3bl2A: undetectable 1uw6B-3bl2A: undetectable	1uw6A-3bl2A: 18.60 1uw6B-3bl2A: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UW6_D_NCTD1208_1 (ACETYLCHOLINE-BINDIN G PROTEIN)	3bl2	V-BCL-2 (Murid gammaherpesvirus 4)	4 / 8	THR A 15 CYH A 99 LEU A 115 MET A 119	None	1.08A	1uw6D-3bl2A: undetectable 1uw6E-3bl2A: undetectable	1uw6D-3bl2A: 18.60 1uw6E-3bl2A: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UW6_G_NCTG1206_1 (ACETYLCHOLINE-BINDIN G PROTEIN)	3bl2	V-BCL-2 (Murid gammaherpesvirus 4)	4 / 8	THR A 15 CYH A 99 LEU A 115 MET A 119	None	1.07A	1uw6G-3bl2A: undetectable 1uw6H-3bl2A: undetectable	1uw6G-3bl2A: 18.60 1uw6H-3bl2A: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UW6_P_NCTP1206_1 (ACETYLCHOLINE-BINDIN G PROTEIN)	3bl2	V-BCL-2 (Murid gammaherpesvirus 4)	4 / 8	THR A 15 CYH A 99 LEU A 115 MET A 119	None	1.03A	1uw6P-3bl2A: undetectable 1uw6Q-3bl2A: undetectable	1uw6P-3bl2A: 18.60 1uw6Q-3bl2A: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1UW6_T_NCTT1208_1 (ACETYLCHOLINE-BINDIN G PROTEIN)	3bl2	V-BCL-2 (Murid gammaherpesvirus 4)	4 / 8	LEU A 115 MET A 119 THR A 15 CYH A 99	None	1.06A	1uw6P-3bl2A: undetectable 1uw6T-3bl2A: undetectable	1uw6P-3bl2A: 18.60 1uw6T-3bl2A: 18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WSV_A_THHA3001_0 (AMINOMETHYLTRANSFERA SE)	3bl2	V-BCL-2 (Murid gammaherpesvirus 4)	6 / 12	VAL A 21 PHE A 75 MET A 119 TYR A 97 ARG A 49 LEU A 64	None	1.25A	1wsvA-3bl2A: undetectable	1wsvA-3bl2A: 16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VQR_A_ACTA1002_0 (PUTATIVE OXIDOREDUCTASE)	3bl2	V-BCL-2 (Murid gammaherpesvirus 4)	4 / 6	GLY A 95 VAL A 94 ASP A 93 THR A 45	None	1.04A	3vqrA-3bl2A: undetectable	3vqrA-3bl2A: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VQR_B_ACTB1002_0 (PUTATIVE OXIDOREDUCTASE)	3bl2	V-BCL-2 (Murid gammaherpesvirus 4)	4 / 5	GLY A 95 VAL A 94 ASP A 93 THR A 45	None	1.05A	3vqrB-3bl2A: undetectable	3vqrB-3bl2A: 18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TVT_A_ASCA302_0 (THAUMATIN-1)	3bl2	V-BCL-2 (Murid gammaherpesvirus 4)	3 / 3	ARG A 49 GLN A 46 GLU A 100	None	0.86A	4tvtA-3bl2A: undetectable	4tvtA-3bl2A: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VEU_A_RITA602_2 (CYTOCHROME P450 3A5)	3bl2	V-BCL-2 (Murid gammaherpesvirus 4)	3 / 3	ARG A 96 PHE A 122 LEU A 115	None	0.83A	5veuA-3bl2A: undetectable	5veuA-3bl2A: 15.04

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1UW6_A_NCTA1208_1","ACETYLCHOLINE-BINDING PROTEIN;ACETYLCHOLINE-BINDING PROTEIN","3bl2","V-BCL-2","Murid gammaherpesvirus 4",4,"THR A  15;CYH A  99;LEU A 115;MET A 119","None","1.04A","1uw6A-3bl2A:undetectable;1uw6B-3bl2A:undetectable","1uw6A-3bl2A:18.60;1uw6B-3bl2A:18.60"],["1UW6_D_NCTD1208_1","ACETYLCHOLINE-BINDING PROTEIN;ACETYLCHOLINE-BINDING PROTEIN","3bl2","V-BCL-2","Murid gammaherpesvirus 4",4,"THR A  15;CYH A  99;LEU A 115;MET A 119","None","1.08A","1uw6D-3bl2A:undetectable;1uw6E-3bl2A:undetectable","1uw6D-3bl2A:18.60;1uw6E-3bl2A:18.60"],["1UW6_G_NCTG1206_1","ACETYLCHOLINE-BINDING PROTEIN;ACETYLCHOLINE-BINDING PROTEIN","3bl2","V-BCL-2","Murid gammaherpesvirus 4",4,"THR A  15;CYH A  99;LEU A 115;MET A 119","None","1.07A","1uw6G-3bl2A:undetectable;1uw6H-3bl2A:undetectable","1uw6G-3bl2A:18.60;1uw6H-3bl2A:18.60"],["1UW6_P_NCTP1206_1","ACETYLCHOLINE-BINDING PROTEIN;ACETYLCHOLINE-BINDING PROTEIN","3bl2","V-BCL-2","Murid gammaherpesvirus 4",4,"THR A  15;CYH A  99;LEU A 115;MET A 119","None","1.03A","1uw6P-3bl2A:undetectable;1uw6Q-3bl2A:undetectable","1uw6P-3bl2A:18.60;1uw6Q-3bl2A:18.60"],["1UW6_T_NCTT1208_1","ACETYLCHOLINE-BINDING PROTEIN;ACETYLCHOLINE-BINDING PROTEIN","3bl2","V-BCL-2","Murid gammaherpesvirus 4",4,"LEU A 115;MET A 119;THR A  15;CYH A  99","None","1.06A","1uw6P-3bl2A:undetectable;1uw6T-3bl2A:undetectable","1uw6P-3bl2A:18.60;1uw6T-3bl2A:18.60"],["1WSV_A_THHA3001_0","AMINOMETHYLTRANSFERASE","3bl2","V-BCL-2","Murid gammaherpesvirus 4",6,"VAL A  21;PHE A  75;MET A 119;TYR A  97;ARG A  49;LEU A  64","None","1.25A","1wsvA-3bl2A:undetectable","1wsvA-3bl2A:16.27"],["3VQR_A_ACTA1002_0","PUTATIVE OXIDOREDUCTASE","3bl2","V-BCL-2","Murid gammaherpesvirus 4",4,"GLY A  95;VAL A  94;ASP A  93;THR A  45","None","1.04A","3vqrA-3bl2A:undetectable","3vqrA-3bl2A:18.15"],["3VQR_B_ACTB1002_0","PUTATIVE OXIDOREDUCTASE","3bl2","V-BCL-2","Murid gammaherpesvirus 4",4,"GLY A  95;VAL A  94;ASP A  93;THR A  45","None","1.05A","3vqrB-3bl2A:undetectable","3vqrB-3bl2A:18.15"],["4TVT_A_ASCA302_0","THAUMATIN-1","3bl2","V-BCL-2","Murid gammaherpesvirus 4",3,"ARG A  49;GLN A  46;GLU A 100","None","0.86A","4tvtA-3bl2A:undetectable","4tvtA-3bl2A:18.36"],["5VEU_A_RITA602_2","CYTOCHROME P450 3A5","3bl2","V-BCL-2","Murid gammaherpesvirus 4",3,"ARG A  96;PHE A 122;LEU A 115","None","0.83A","5veuA-3bl2A:undetectable","5veuA-3bl2A:15.04"]]