SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bl9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		3 / 3 LEU A  53
HIS A  65
LYS A  51
 None
 1.04A 1y7iA-3bl9A:
undetectable		 1y7iA-3bl9A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DRD_A_MIYA2001_1
(ACRB)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		5 / 9 GLY A 248
ASN A 243
ILE A 244
ALA A 220
VAL A 278
 None
 1.35A 2drdA-3bl9A:
undetectable		 2drdA-3bl9A:
14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		3 / 3 LEU A 327
PRO A 326
LEU A 330
 None
 0.53A 2po5B-3bl9A:
undetectable		 2po5B-3bl9A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		3 / 3 LEU A 327
PRO A 326
LEU A 330
 None
 0.48A 2po7B-3bl9A:
undetectable		 2po7B-3bl9A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_D_DXCD92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		4 / 5 VAL A  82
GLU A 185
LYS A  42
PHE A  44
 None
DD2  A 901 (-2.8A)
None
None
 1.49A 3rv5C-3bl9A:
undetectable
3rv5D-3bl9A:
undetectable		 3rv5C-3bl9A:
14.29
3rv5D-3bl9A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		4 / 5 PHE A 319
TYR A 269
THR A 154
ILE A 151
 None
 1.22A 4jx1E-3bl9A:
undetectable		 4jx1E-3bl9A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		4 / 5 LEU A 327
PRO A 326
LEU A 330
ILE A 161
 None
 0.98A 4klrA-3bl9A:
undetectable		 4klrA-3bl9A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_D_HQED503_1
(CATALASE)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		5 / 9 PRO A 271
LEU A 166
GLN A 169
LEU A 270
ASP A 325
 None
 1.23A 4qopD-3bl9A:
0.6		 4qopD-3bl9A:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		4 / 6 ARG A 228
ASP A 232
HIS A 237
ILE A 227
 None
 1.26A 5a06A-3bl9A:
undetectable		 5a06A-3bl9A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXE_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		4 / 8 LEU A 230
LEU A 298
HIS A 311
LEU A 305
 None
 1.12A 5dxeA-3bl9A:
undetectable		 5dxeA-3bl9A:
23.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		4 / 6 VAL A 278
LEU A 298
CYH A 222
LEU A 240
 None
 0.99A 5hrqB-3bl9A:
undetectable
5hrqI-3bl9A:
undetectable
5hrqJ-3bl9A:
undetectable		 5hrqB-3bl9A:
9.24
5hrqI-3bl9A:
8.59
5hrqJ-3bl9A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM9_B_ADNB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		5 / 12 ILE A 179
ASP A 205
SER A 272
HIS A 277
HIS A 279
 None
DD2  A 901 (-3.2A)
DD2  A 901 ( 3.7A)
None
None
 0.70A 5km9B-3bl9A:
10.6		 5km9B-3bl9A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UVM_B_ADNB207_1
(HISTIDINE TRIAD
(HIT) PROTEIN)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		6 / 12 VAL A 176
ILE A 179
ILE A 203
ASP A 205
HIS A 277
HIS A 279
 None
None
DD2  A 901 ( 4.2A)
DD2  A 901 (-3.2A)
None
None
 1.18A 5uvmB-3bl9A:
9.9		 5uvmB-3bl9A:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 3bl9 SCAVENGER
MRNA-DECAPPING
ENZYME DCPS
(Homo
sapiens) 		4 / 8 LEU A 230
LEU A 298
HIS A 311
LEU A 305
 None
 1.12A 6cbzA-3bl9A:
undetectable		 6cbzA-3bl9A:
17.18