SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bma'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		4 / 8 PHE A  54
TYR A 152
GLY A 107
GLY A 108
 None
None
SO4  A   3 (-3.5A)
SO4  A   3 (-3.9A)
 0.90A 1ekjE-3bmaA:
undetectable
1ekjF-3bmaA:
undetectable		 1ekjE-3bmaA:
20.72
1ekjF-3bmaA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G5Y_C_9CRC502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		5 / 10 ALA A 362
ARG A  97
LEU A 396
PHE A 322
ILE A 321
 None
 1.10A 1g5yC-3bmaA:
undetectable		 1g5yC-3bmaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HBP_A_RTLA184_0
(RETINOL BINDING
PROTEIN)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		5 / 11 PHE A 412
ALA A 170
ALA A 174
LEU A 158
GLN A 157
 None
 1.28A 1hbpA-3bmaA:
undetectable		 1hbpA-3bmaA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		5 / 7 PHE A 161
PHE A 116
PHE A 153
PHE A 149
VAL A 191
 None
 1.46A 1lh6A-3bmaA:
undetectable		 1lh6A-3bmaA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		3 / 3 GLU A 273
ASN A 264
TRP A 382
 None
 1.19A 1r15C-3bmaA:
1.3		 1r15C-3bmaA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		3 / 3 GLU A 273
ASN A 264
TRP A 382
 None
 1.16A 1r15D-3bmaA:
undetectable		 1r15D-3bmaA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		3 / 3 GLU A 273
ASN A 264
TRP A 382
 None
 1.17A 1r15E-3bmaA:
undetectable		 1r15E-3bmaA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		3 / 3 GLU A 273
ASN A 264
TRP A 382
 None
 1.16A 1r15F-3bmaA:
1.5		 1r15F-3bmaA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		4 / 4 GLY A 107
SER A  78
ILE A 378
HIS A 379
 SO4  A   3 (-3.5A)
SO4  A   3 ( 2.7A)
None
SO4  A   3 (-4.2A)
 1.30A 1yajJ-3bmaA:
undetectable		 1yajJ-3bmaA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_J_BEZJ5041_0
(CES1 PROTEIN)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		4 / 4 GLY A 108
SER A  78
ILE A 378
HIS A 379
 SO4  A   3 (-3.9A)
SO4  A   3 ( 2.7A)
None
SO4  A   3 (-4.2A)
 1.41A 1yajJ-3bmaA:
undetectable		 1yajJ-3bmaA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		5 / 12 GLY A 368
ASN A 328
LEU A 386
ASP A 389
PHE A 388
 None
 1.36A 2b9eA-3bmaA:
undetectable		 2b9eA-3bmaA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		5 / 12 PHE A  75
GLY A 105
ASN A 113
TYR A 132
PHE A 313
 None
 1.45A 3a27A-3bmaA:
1.1		 3a27A-3bmaA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		4 / 8 ASN A 232
THR A  50
GLN A  59
SER A 226
 None
GOL  A 436 (-3.8A)
None
None
 1.09A 3kp2A-3bmaA:
undetectable
3kp2B-3bmaA:
undetectable		 3kp2A-3bmaA:
16.75
3kp2B-3bmaA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UGR_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		5 / 12 LEU A 310
SER A 111
TYR A 173
SER A 413
PHE A 139
 None
 1.24A 3ugrA-3bmaA:
2.5		 3ugrA-3bmaA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_F_5FWF1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		4 / 6 GLU A 339
LYS A 329
PRO A 326
LYS A 366
 None
 1.45A 4a7tF-3bmaA:
undetectable		 4a7tF-3bmaA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_D_ACTD504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		3 / 3 GLY A  76
SER A  77
TRP A 138
 None
SO4  A   3 (-3.4A)
SO4  A   3 (-4.8A)
 0.97A 4e7cD-3bmaA:
undetectable		 4e7cD-3bmaA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		5 / 12 LEU A  64
VAL A  72
PHE A 313
VAL A 133
VAL A 318
 None
 1.20A 4ib4A-3bmaA:
undetectable		 4ib4A-3bmaA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		3 / 3 LYS A 258
LEU A 383
ALA A 261
 None
 0.78A 4iizA-3bmaA:
undetectable		 4iizA-3bmaA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		4 / 5 ASN A 142
GLY A 143
ASP A 376
ASP A 145
 None
 1.05A 4n48B-3bmaA:
undetectable		 4n48B-3bmaA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_B_ACTB201_0
(RETINOL-BINDING
PROTEIN 2)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		4 / 5 TYR A 173
TYR A 144
LEU A 112
GLN A 180
 None
 1.38A 4qztB-3bmaA:
undetectable		 4qztB-3bmaA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_B_ACTB202_0
(RETINOL-BINDING
PROTEIN 2)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		4 / 7 TYR A 173
TYR A 144
LEU A 112
GLN A 180
 None
 1.39A 4qzuB-3bmaA:
undetectable		 4qzuB-3bmaA:
15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_1
(CYTOCHROME P450 2D6)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		5 / 12 GLY A 384
LEU A 386
ALA A 261
ASP A 260
VAL A  90
 None
 1.02A 4wnwB-3bmaA:
undetectable		 4wnwB-3bmaA:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YHA_A_MZMA303_1
(ALPHA-CARBONIC
ANHYDRASE)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		5 / 12 LYS A 375
ASP A  84
VAL A 257
LEU A 386
ALA A 387
 None
 1.38A 4yhaA-3bmaA:
undetectable		 4yhaA-3bmaA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AMI_B_EF2B151_1
(CEREBLON ISOFORM 4)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		4 / 8 ASN A 319
PRO A 320
PHE A 313
SER A 314
 None
 1.35A 5amiB-3bmaA:
undetectable		 5amiB-3bmaA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		5 / 12 GLY A 368
GLY A 384
ASN A 328
ASP A 333
ASP A 367
 None
 1.05A 5yn6A-3bmaA:
undetectable		 5yn6A-3bmaA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		5 / 12 GLY A 368
GLY A 384
ASN A 328
ASP A 333
ASP A 367
 None
 1.03A 5yniA-3bmaA:
undetectable		 5yniA-3bmaA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		5 / 12 GLY A 368
GLY A 384
ASN A 328
ASP A 333
ASP A 367
 None
 1.04A 5ynmA-3bmaA:
undetectable		 5ynmA-3bmaA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 3bma D-ALANYL-LIPOTEICHOI
C ACID SYNTHETASE
(Streptococcus
pneumoniae) 		4 / 5 ALA A 110
SER A  77
GLY A 107
TYR A 152
 None
SO4  A   3 (-3.4A)
SO4  A   3 (-3.5A)
None
 0.97A 5yodB-3bmaA:
undetectable		 5yodB-3bmaA:
16.91