SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bmb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 3bmb REGULATOR OF
NUCLEOSIDE
DIPHOSPHATE KINASE
(Escherichia
coli) 		5 / 11 SER A  58
LEU A  75
LEU A  38
VAL A  54
ILE A   8
 None
 1.35A 1ee2A-3bmbA:
undetectable		 1ee2A-3bmbA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 3bmb REGULATOR OF
NUCLEOSIDE
DIPHOSPHATE KINASE
(Escherichia
coli) 		5 / 11 SER A  58
LEU A  75
LEU A  38
VAL A  54
ILE A   8
 None
 1.42A 1ee2B-3bmbA:
undetectable		 1ee2B-3bmbA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA443_1
(ALPHA AMYLASE)		 3bmb REGULATOR OF
NUCLEOSIDE
DIPHOSPHATE KINASE
(Escherichia
coli) 		4 / 8 THR A  55
ASN A   9
LEU A  11
ASP A  12
 None
 0.91A 1mxgA-3bmbA:
undetectable		 1mxgA-3bmbA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 3bmb REGULATOR OF
NUCLEOSIDE
DIPHOSPHATE KINASE
(Escherichia
coli) 		5 / 12 ALA A  36
ASP A  39
GLU A  37
LEU A  38
GLY A  27
 None
 1.12A 2jfaB-3bmbA:
undetectable		 2jfaB-3bmbA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 3bmb REGULATOR OF
NUCLEOSIDE
DIPHOSPHATE KINASE
(Escherichia
coli) 		4 / 4 LEU A  75
LEU A 119
GLN A 127
GLU A 125
 None
 1.14A 4i41A-3bmbA:
undetectable		 4i41A-3bmbA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCU_A_SAMA603_0
(CYSTATHIONINE
BETA-SYNTHASE)		 3bmb REGULATOR OF
NUCLEOSIDE
DIPHOSPHATE KINASE
(Escherichia
coli) 		4 / 7 GLN A 127
THR A  55
ILE A   8
ASP A  12
 None
 1.08A 4pcuA-3bmbA:
undetectable		 4pcuA-3bmbA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 3bmb REGULATOR OF
NUCLEOSIDE
DIPHOSPHATE KINASE
(Escherichia
coli) 		4 / 6 LEU A  34
LEU A  38
TYR A  77
MET A  56
 None
None
SO4  A 137 (-4.7A)
None
 1.08A 6f6sA-3bmbA:
undetectable
6f6sB-3bmbA:
undetectable		 6f6sA-3bmbA:
20.44
6f6sB-3bmbA:
21.48