SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bn3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 4 LEU B  97
PRO B  98
LEU B 190
ARG B 128
 None
 0.74A 1hrkB-3bn3B:
undetectable		 1hrkB-3bn3B:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		5 / 12 LEU B  40
LEU B  52
ARG B  47
LEU B   7
THR B  64
 None
 1.31A 1ya3B-3bn3B:
undetectable		 1ya3B-3bn3B:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 4 LEU B  97
PRO B  98
LEU B 190
ARG B 128
 None
 0.82A 2hrcA-3bn3B:
undetectable		 2hrcA-3bn3B:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 4 LEU B  97
PRO B  98
LEU B 190
ARG B 128
 None
 0.78A 2hrcB-3bn3B:
undetectable		 2hrcB-3bn3B:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		5 / 12 LEU B  40
LEU B  52
ARG B  47
LEU B   7
THR B  64
 None
 1.30A 2oaxA-3bn3B:
undetectable		 2oaxA-3bn3B:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		5 / 12 LEU B  40
LEU B  52
ARG B  47
LEU B   7
THR B  64
 None
 1.32A 2oaxB-3bn3B:
undetectable		 2oaxB-3bn3B:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		5 / 12 LEU B  40
LEU B  52
ARG B  47
LEU B   7
THR B  64
 None
 1.26A 2oaxC-3bn3B:
undetectable		 2oaxC-3bn3B:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 4 LEU B  97
PRO B  98
LEU B 190
ARG B 128
 None
 0.67A 2pnjB-3bn3B:
undetectable		 2pnjB-3bn3B:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		3 / 3 LEU B  97
PRO B  98
ARG B 128
 None
 0.66A 2qd5A-3bn3B:
undetectable		 2qd5A-3bn3B:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA3_0
(FERROCHELATASE)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		3 / 3 PRO B  98
LEU B 190
ARG B 128
 None
 0.82A 3aqiA-3bn3B:
undetectable		 3aqiA-3bn3B:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		5 / 10 THR B  45
THR B  38
LEU B  52
LEU B  36
GLY B  35
 None
 1.30A 3lxiA-3bn3B:
undetectable		 3lxiA-3bn3B:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		5 / 12 LEU B  40
LEU B  52
ARG B  47
LEU B   7
THR B  64
 None
 1.35A 3vhuA-3bn3B:
undetectable		 3vhuA-3bn3B:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		5 / 9 THR B  45
THR B  38
LEU B  52
LEU B  36
GLY B  35
 None
 1.32A 4c9kA-3bn3B:
undetectable		 4c9kA-3bn3B:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		5 / 9 THR B  45
THR B  38
LEU B  52
LEU B  36
GLY B  35
 None
 1.31A 4c9pA-3bn3B:
undetectable		 4c9pA-3bn3B:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		5 / 10 THR B  45
THR B  38
LEU B  52
LEU B  36
GLY B  35
 None
 1.32A 4c9pB-3bn3B:
undetectable		 4c9pB-3bn3B:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		3 / 3 GLY B  81
GLU B  63
THR B  64
 None
 0.55A 4kouA-3bn3B:
undetectable		 4kouA-3bn3B:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 5 ARG B 119
GLY B 147
ALA B 148
GLY B 117
 GOL  B 204 ( 4.0A)
None
GOL  B 204 (-4.2A)
None
 0.92A 4u9uA-3bn3B:
undetectable		 4u9uA-3bn3B:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 5 ARG B 119
GLY B 147
ALA B 148
GLY B 117
 GOL  B 204 ( 4.0A)
None
GOL  B 204 (-4.2A)
None
 0.89A 4u9uB-3bn3B:
undetectable		 4u9uB-3bn3B:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYF_B_TA1B502_1
(TUBULIN BETA CHAIN)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		5 / 12 LEU B 133
ALA B 156
PRO B  98
ARG B 191
LEU B  97
 None
 1.40A 5syfB-3bn3B:
undetectable		 5syfB-3bn3B:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 4 ARG B 135
GLU B 132
GLU B 170
ARG B 168
 None
 1.14A 6fk2A-3bn3B:
undetectable		 6fk2A-3bn3B:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FK2_A_SORA302_0
(GALECTIN-3)		 3bn3 INTERCELLULAR
ADHESION MOLECULE 5
(Homo
sapiens) 		4 / 4 ARG B 168
GLU B 170
GLU B 132
ARG B 135
 None
 1.01A 6fk2A-3bn3B:
undetectable		 6fk2A-3bn3B:
21.50