SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bn6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 3bn6 LACTADHERIN
(Bos
taurus) 		5 / 12 GLY A   6
VAL A 138
GLY A  72
ILE A  74
ILE A  62
 None
 0.70A 1hxbA-3bn6A:
undetectable		 1hxbA-3bn6A:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJL_B_SAMB400_0
(METHIONINE REPRESSOR
PROTEIN METJ)		 3bn6 LACTADHERIN
(Bos
taurus) 		5 / 9 LEU A 155
GLU A 154
HIS A 124
LEU A  40
GLY A  77
 None
 1.47A 1mjlA-3bn6A:
undetectable
1mjlB-3bn6A:
undetectable		 1mjlA-3bn6A:
21.25
1mjlB-3bn6A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 3bn6 LACTADHERIN
(Bos
taurus) 		5 / 12 TYR A  90
LEU A 151
ILE A  62
VAL A 138
VAL A  92
 None
 1.16A 2g72B-3bn6A:
undetectable		 2g72B-3bn6A:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 3bn6 LACTADHERIN
(Bos
taurus) 		4 / 6 ARG A 136
GLY A  65
PRO A  13
THR A  11
 None
 1.23A 2m2oB-3bn6A:
undetectable		 2m2oB-3bn6A:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_A_ACTA1003_0
(FORMIN-LIKE PROTEIN
3)		 3bn6 LACTADHERIN
(Bos
taurus) 		4 / 5 ASN A  54
ARG A 148
ASN A 147
TRP A 145
 None
 1.25A 4eahA-3bn6A:
undetectable
4eahE-3bn6A:
undetectable		 4eahA-3bn6A:
16.92
4eahE-3bn6A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3bn6 LACTADHERIN
(Bos
taurus) 		5 / 8 GLY A 157
GLY A   6
LEU A   7
VAL A 153
GLU A 154
 None
 1.48A 4fgzA-3bn6A:
undetectable		 4fgzA-3bn6A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3bn6 LACTADHERIN
(Bos
taurus) 		6 / 9 ALA A  88
VAL A  87
ILE A 140
LEU A 151
ILE A  73
ASN A 127
 None
 1.38A 5nunA-3bn6A:
undetectable		 5nunA-3bn6A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 3bn6 LACTADHERIN
(Bos
taurus) 		5 / 12 LEU A 156
ILE A  73
VAL A 138
TYR A 104
PHE A 133
 None
 1.40A 5vlmB-3bn6A:
undetectable		 5vlmB-3bn6A:
17.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_0
(HIV-1 PROTEASE)		 3bn6 LACTADHERIN
(Bos
taurus) 		5 / 12 GLY A   6
VAL A 138
GLY A  72
ILE A  74
ILE A  62
 None
 0.70A 6dj1A-3bn6A:
undetectable		 6dj1A-3bn6A:
18.71