SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bn9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_F_ACTF3008_0
(BETA-CARBONIC
ANHYDRASE)		 3bn9 E2 FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 8 GLN D   6
VAL D 109
GLY D   8
GLY D   9
 None
 0.74A 1ekjE-3bn9D:
undetectable
1ekjF-3bn9D:
undetectable		 1ekjE-3bn9D:
20.75
1ekjF-3bn9D:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_A_8MOA501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 3bn9 E2 FAB HEAVY CHAIN
(Homo
sapiens) 		6 / 11 PHE D  29
ASN D  73
GLY D  54
THR D  57
ILE D  69
LEU D  78
 None
 1.48A 1z11A-3bn9D:
undetectable		 1z11A-3bn9D:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3bn9 E2 FAB HEAVY CHAIN
(Homo
sapiens) 		4 / 7 ALA D  88
THR D  87
VAL D 109
GLU D  85
 None
 0.82A 5ecoD-3bn9D:
undetectable		 5ecoD-3bn9D:
19.31