SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bnw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NB9_A_RBFA401_1
(HYPOTHETICAL PROTEIN
FLJ11149)		 3bnw RIBOFLAVIN KINASE,
PUTATIVE
(Trypanosoma
brucei) 		5 / 9 SER A  77
GLU A  92
ARG A 117
LEU A 128
ASP A 135
 None
 0.83A 1nb9A-3bnwA:
17.0		 1nb9A-3bnwA:
27.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3bnw RIBOFLAVIN KINASE,
PUTATIVE
(Trypanosoma
brucei) 		6 / 11 VAL A  51
GLU A  92
ARG A 117
LEU A 128
ILE A 132
ASP A 135
 None
 0.97A 1t6zA-3bnwA:
7.5		 1t6zA-3bnwA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_B_RBFB596_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 3bnw RIBOFLAVIN KINASE,
PUTATIVE
(Trypanosoma
brucei) 		5 / 11 VAL A  51
ARG A 117
LEU A 128
ILE A 132
ASP A 135
 None
 0.59A 1t6zB-3bnwA:
7.9		 1t6zB-3bnwA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3bnw RIBOFLAVIN KINASE,
PUTATIVE
(Trypanosoma
brucei) 		4 / 7 LEU A 143
GLN A 144
LEU A 113
PHE A 151
 None
 1.00A 2dysC-3bnwA:
undetectable
2dysJ-3bnwA:
undetectable		 2dysC-3bnwA:
21.11
2dysJ-3bnwA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3Y_A_OBNA6000_1
(NA, K-ATPASE ALPHA
SUBUNIT)		 3bnw RIBOFLAVIN KINASE,
PUTATIVE
(Trypanosoma
brucei) 		5 / 10 GLU A 168
GLY A  14
VAL A  16
ALA A 106
PHE A 157
 None
 1.09A 3a3yA-3bnwA:
undetectable		 3a3yA-3bnwA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3bnw RIBOFLAVIN KINASE,
PUTATIVE
(Trypanosoma
brucei) 		4 / 6 LEU A 143
GLN A 144
LEU A 113
PHE A 151
 None
 0.95A 3ag1C-3bnwA:
undetectable
3ag1J-3bnwA:
undetectable		 3ag1C-3bnwA:
21.11
3ag1J-3bnwA:
17.65