SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bo6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E72_M_ASCM995_0
(MYROSINASE MA1)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		4 / 7 ILE A 132
ARG A  91
PHE A  76
PHE A 118
 None
 1.23A 1e72M-3bo6A:
undetectable		 1e72M-3bo6A:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_B_SAMB1500_0
(ASPARTOKINASE)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		5 / 7 SER A  50
SER A 185
ARG A 186
LEU A 124
GLU A  54
 None
 1.33A 2cdqB-3bo6A:
1.7		 2cdqB-3bo6A:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZTH_A_SAMA305_0
(CATECHOL
O-METHYLTRANSFERASE)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		5 / 12 VAL A 114
TYR A 209
SER A 200
HIS A 106
ARG A 213
 None
None
SO4  A   1 ( 4.5A)
SO4  A   1 (-3.9A)
SO4  A   1 (-3.8A)
 1.27A 2zthA-3bo6A:
undetectable		 2zthA-3bo6A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIA_A_SAMA206_0
(UPF0217 PROTEIN
MJ1640)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		4 / 6 LEU A 187
GLY A 191
LEU A 121
SER A 122
 None
 0.74A 3aiaA-3bo6A:
undetectable		 3aiaA-3bo6A:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGY_A_GLYA510_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		4 / 6 ILE A 180
GLU A 181
ALA A 240
ASN A 206
 None
 1.07A 3pgyA-3bo6A:
undetectable
3pgyB-3bo6A:
undetectable		 3pgyA-3bo6A:
19.66
3pgyB-3bo6A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_A_FK5A200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		5 / 11 TYR A 212
ASP A 103
ILE A 180
ILE A 132
MET A  44
 None
 1.38A 4dz2A-3bo6A:
undetectable
4dz2B-3bo6A:
undetectable		 4dz2A-3bo6A:
20.91
4dz2B-3bo6A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DZ2_B_FK5B200_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		5 / 11 MET A  44
TYR A 212
ASP A 103
ILE A 180
ILE A 132
 None
 1.39A 4dz2A-3bo6A:
undetectable
4dz2B-3bo6A:
undetectable		 4dz2A-3bo6A:
20.91
4dz2B-3bo6A:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_A_715A801_1
(DIPEPTIDYL PEPTIDASE
4)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		5 / 12 ARG A 217
GLU A 233
TYR A 168
TYR A 212
ASN A 214
 None
 1.45A 4ffwA-3bo6A:
undetectable		 4ffwA-3bo6A:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		5 / 9 ILE A 107
PHE A 105
LEU A 183
VAL A 159
LEU A 157
 None
 1.12A 4g1bC-3bo6A:
undetectable		 4g1bC-3bo6A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		4 / 7 LEU A  33
LEU A 238
ARG A 177
LEU A 173
 None
 0.71A 4wg0B-3bo6A:
undetectable
4wg0C-3bo6A:
undetectable		 4wg0B-3bo6A:
9.24
4wg0C-3bo6A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		4 / 7 LEU A 238
ARG A 177
LEU A 173
LEU A  33
 None
 0.80A 4wg0L-3bo6A:
undetectable
4wg0M-3bo6A:
undetectable		 4wg0L-3bo6A:
9.24
4wg0M-3bo6A:
9.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_A_ACTA1923_0
(BETA-XYLOSIDASE)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		3 / 3 ASP A 201
ARG A 213
TYR A 212
 None
SO4  A   1 (-3.8A)
None
 0.85A 5a7mA-3bo6A:
undetectable		 5a7mA-3bo6A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A7M_B_ACTB1924_0
(BETA-XYLOSIDASE)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		3 / 3 ASP A 201
ARG A 213
TYR A 212
 None
SO4  A   1 (-3.8A)
None
 0.84A 5a7mB-3bo6A:
undetectable		 5a7mB-3bo6A:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		3 / 3 MET A  47
GLN A  46
ARG A  45
 None
 0.97A 5ewzB-3bo6A:
undetectable		 5ewzB-3bo6A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		3 / 3 MET A  47
GLN A  46
ARG A  45
 None
 1.01A 5m35B-3bo6A:
undetectable		 5m35B-3bo6A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		3 / 3 MET A  47
GLN A  46
ARG A  45
 None
 1.06A 5m36A-3bo6A:
undetectable		 5m36A-3bo6A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA609_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		3 / 3 HIS A  38
HIS A  41
ARG A  45
 None
 0.83A 6b58A-3bo6A:
undetectable		 6b58A-3bo6A:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		3 / 3 MET A  47
GLN A  46
ARG A  45
 None
 1.03A 6fn9A-3bo6A:
undetectable		 6fn9A-3bo6A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		3 / 3 MET A  47
GLN A  46
ARG A  45
 None
 1.04A 6fnaB-3bo6A:
undetectable		 6fnaB-3bo6A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 3bo6 HYDROPHILIC PROTEIN,
VIRA PROTEIN
(Chromobacterium
violaceum) 		3 / 3 MET A  47
GLN A  46
ARG A  45
 None
 1.04A 6fnbA-3bo6A:
undetectable		 6fnbA-3bo6A:
21.96