SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bo7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		5 / 10 LEU A 129
THR A 122
ILE A 121
PHE A  93
THR A 134
 None
 1.36A 1i18A-3bo7A:
undetectable
1i18B-3bo7A:
undetectable		 1i18A-3bo7A:
20.53
1i18B-3bo7A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		5 / 10 PHE A  93
THR A 134
LEU A 129
THR A 122
ILE A 121
 None
 1.35A 1i18A-3bo7A:
undetectable
1i18B-3bo7A:
undetectable		 1i18A-3bo7A:
20.53
1i18B-3bo7A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 7 VAL A 171
LEU A  35
SER A  33
PHE A  34
 None
 0.63A 1j8uA-3bo7A:
undetectable		 1j8uA-3bo7A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OPJ_B_STIB4_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 6 LEU A  64
VAL A 145
ILE A  57
ARG A  10
 SO4  A 205 (-4.3A)
None
None
None
 0.89A 1opjB-3bo7A:
undetectable		 1opjB-3bo7A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 8 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.76A 1rtsA-3bo7A:
undetectable		 1rtsA-3bo7A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HYY_A_STIA600_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 6 LEU A  64
VAL A 145
ILE A  57
ARG A  10
 SO4  A 205 (-4.3A)
None
None
None
 0.87A 2hyyA-3bo7A:
undetectable		 2hyyA-3bo7A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 8 ILE A  11
PHE A  34
GLY A  59
GLY A  60
 None
 0.70A 2qx4A-3bo7A:
undetectable
2qx4B-3bo7A:
undetectable		 2qx4A-3bo7A:
25.31
2qx4B-3bo7A:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 6 ILE A  11
PHE A  34
GLY A  59
GLY A  60
 None
 0.74A 2qx6A-3bo7A:
undetectable
2qx6B-3bo7A:
undetectable		 2qx6A-3bo7A:
25.31
2qx6B-3bo7A:
25.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 7 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.71A 2tsrA-3bo7A:
undetectable		 2tsrA-3bo7A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 8 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.76A 2tsrB-3bo7A:
undetectable		 2tsrB-3bo7A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDM_B_AGGB1462_1
(INTEGRIN ALPHA-IIB
INTEGRIN BETA-3)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		5 / 12 PHE A  43
LEU A  64
SER A 106
ASN A 115
ALA A 108
 None
SO4  A 205 (-4.3A)
None
None
None
 1.36A 2vdmA-3bo7A:
undetectable
2vdmB-3bo7A:
undetectable		 2vdmA-3bo7A:
17.61
2vdmB-3bo7A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_A_0LIA1_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 7 LEU A  64
VAL A 145
ILE A  57
ARG A  10
 SO4  A 205 (-4.3A)
None
None
None
 1.02A 3ik3A-3bo7A:
undetectable		 3ik3A-3bo7A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK3_B_0LIB2_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE ABL1)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 7 LEU A  64
VAL A 145
ILE A  57
ARG A  10
 SO4  A 205 (-4.3A)
None
None
None
 1.02A 3ik3B-3bo7A:
undetectable		 3ik3B-3bo7A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 6 PHE A  43
PHE A 119
THR A  46
VAL A 166
 None
 1.23A 3lb3A-3bo7A:
undetectable		 3lb3A-3bo7A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 6 PHE A  43
PHE A 119
THR A  46
VAL A 166
 None
 1.22A 3lb3B-3bo7A:
undetectable		 3lb3B-3bo7A:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_B_NCTB501_1
(CYTOCHROME P450 2A6)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 7 PHE A  43
VAL A 166
GLY A  59
PHE A  34
 None
 0.80A 4ejjB-3bo7A:
undetectable		 4ejjB-3bo7A:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 7 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.78A 4iqqA-3bo7A:
undetectable		 4iqqA-3bo7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 7 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.73A 4iqqB-3bo7A:
undetectable		 4iqqB-3bo7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 7 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.64A 4iqqC-3bo7A:
undetectable		 4iqqC-3bo7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IQQ_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 8 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.71A 4iqqD-3bo7A:
undetectable		 4iqqD-3bo7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 7 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.78A 5h3aB-3bo7A:
undetectable		 5h3aB-3bo7A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_C_MTXC402_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		5 / 12 LEU A 105
ILE A 121
LEU A 143
GLY A 142
ILE A 102
 None
 1.30A 5j7wC-3bo7A:
undetectable		 5j7wC-3bo7A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_A_D16A402_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 7 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.78A 5nooA-3bo7A:
undetectable		 5nooA-3bo7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_B_D16B402_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 7 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.75A 5nooB-3bo7A:
undetectable		 5nooB-3bo7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 7 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.72A 5x5qC-3bo7A:
undetectable		 5x5qC-3bo7A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 8 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.75A 5x5qD-3bo7A:
undetectable		 5x5qD-3bo7A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 6 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.74A 5x5qE-3bo7A:
undetectable		 5x5qE-3bo7A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 3bo7 PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
CYCLOPHILIN-TYPE
(Toxoplasma
gondii) 		4 / 8 ILE A 121
ASP A 144
LEU A 143
GLY A 142
 None
 0.75A 5x5qF-3bo7A:
undetectable		 5x5qF-3bo7A:
21.62