SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3boe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DF7_A_MTXA501_1
(DIHYDROFOLATE
REDUCTASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 ILE A 242
GLN A 228
LEU A 411
PRO A 408
ILE A 429
 None
 0.97A 1df7A-3boeA:
undetectable		 1df7A-3boeA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 CYH A 263
ASP A 265
HIS A 315
CYH A 325
GLY A 326
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.7A)
 0.25A 1ekjA-3boeA:
undetectable
1ekjB-3boeA:
undetectable		 1ekjA-3boeA:
21.54
1ekjB-3boeA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 CYH A 263
ASP A 265
HIS A 315
CYH A 325
GLY A 326
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.7A)
 0.99A 1ekjA-3boeA:
undetectable
1ekjB-3boeA:
undetectable		 1ekjA-3boeA:
21.54
1ekjB-3boeA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 CYH A 263
ASP A 265
HIS A 315
CYH A 325
GLY A 326
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.7A)
 0.30A 1ekjA-3boeA:
undetectable
1ekjB-3boeA:
undetectable		 1ekjA-3boeA:
21.54
1ekjB-3boeA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 CYH A 263
VAL A 264
HIS A 315
CYH A 325
GLY A 326
 CD  A1001 ( 2.4A)
None
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.7A)
 1.40A 1ekjA-3boeA:
undetectable
1ekjB-3boeA:
undetectable		 1ekjA-3boeA:
21.54
1ekjB-3boeA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		4 / 7 CYH A 263
ASP A 265
HIS A 315
GLY A 326
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
ACT  A1002 (-3.7A)
 0.26A 1ekjE-3boeA:
undetectable
1ekjF-3boeA:
undetectable		 1ekjE-3boeA:
21.54
1ekjF-3boeA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		4 / 7 CYH A 263
ASP A 265
HIS A 315
GLY A 326
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
ACT  A1002 (-3.7A)
 0.95A 1ekjE-3boeA:
undetectable
1ekjF-3boeA:
undetectable		 1ekjE-3boeA:
21.54
1ekjF-3boeA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 CYH A 263
ASP A 265
HIS A 315
CYH A 325
GLY A 326
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.7A)
 0.30A 1ekjG-3boeA:
undetectable
1ekjH-3boeA:
undetectable		 1ekjG-3boeA:
21.54
1ekjH-3boeA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 CYH A 263
ASP A 265
HIS A 315
CYH A 325
GLY A 326
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.7A)
 0.98A 1ekjG-3boeA:
undetectable
1ekjH-3boeA:
undetectable		 1ekjG-3boeA:
21.54
1ekjH-3boeA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		4 / 6 CYH A 263
ASP A 265
HIS A 315
CYH A 325
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
 0.28A 1ekjG-3boeA:
undetectable
1ekjH-3boeA:
undetectable		 1ekjG-3boeA:
21.54
1ekjH-3boeA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		4 / 6 CYH A 263
VAL A 264
HIS A 315
CYH A 325
 CD  A1001 ( 2.4A)
None
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
 1.40A 1ekjG-3boeA:
undetectable
1ekjH-3boeA:
undetectable		 1ekjG-3boeA:
21.54
1ekjH-3boeA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		4 / 7 GLY A 282
PRO A 280
HIS A 288
ALA A 413
 None
 0.97A 1gxsA-3boeA:
undetectable
1gxsB-3boeA:
undetectable		 1gxsA-3boeA:
20.42
1gxsB-3boeA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		4 / 7 PRO A 277
ILE A 260
PRO A 280
GLY A 282
 None
 0.99A 2y7kA-3boeA:
undetectable		 2y7kA-3boeA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 ILE A 283
GLY A 282
VAL A 314
ALA A 285
VAL A 305
 None
 0.90A 3fpjA-3boeA:
undetectable		 3fpjA-3boeA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 ILE A 283
GLY A 282
VAL A 314
ILE A 260
VAL A 305
 None
 0.89A 3fpjA-3boeA:
undetectable		 3fpjA-3boeA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 10 CYH A 263
ASP A 265
HIS A 315
CYH A 325
GLY A 326
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.7A)
 0.39A 3ucjA-3boeA:
undetectable		 3ucjA-3boeA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 10 CYH A 263
VAL A 264
HIS A 315
CYH A 325
GLY A 326
 CD  A1001 ( 2.4A)
None
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.7A)
 1.21A 3ucjA-3boeA:
undetectable		 3ucjA-3boeA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 10 CYH A 263
ASP A 265
HIS A 315
CYH A 325
GLY A 326
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.7A)
 0.41A 3ucjB-3boeA:
undetectable		 3ucjB-3boeA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 10 CYH A 263
VAL A 264
HIS A 315
CYH A 325
GLY A 326
 CD  A1001 ( 2.4A)
None
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.7A)
 1.22A 3ucjB-3boeA:
undetectable		 3ucjB-3boeA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 VAL A 264
LEU A 384
ILE A 376
VAL A 430
LEU A 378
 None
 1.09A 3w68A-3boeA:
undetectable		 3w68A-3boeA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 ILE A 242
GLN A 228
LEU A 411
PRO A 408
ILE A 429
 None
 1.02A 4m2xG-3boeA:
undetectable		 4m2xG-3boeA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA602_1
(SERUM ALBUMIN)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 ASP A 239
ASN A 426
ALA A 427
VAL A 374
GLU A 419
 None
 1.16A 4zbqA-3boeA:
undetectable		 4zbqA-3boeA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_DIFA601_1
(SERUM ALBUMIN)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 9 ASP A 239
ASN A 426
ALA A 427
VAL A 374
GLU A 419
 None
 1.18A 4zbrA-3boeA:
undetectable		 4zbrA-3boeA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 9 ILE A 412
ALA A 414
ILE A 229
ALA A 232
LEU A 233
 None
 1.02A 5mvmA-3boeA:
undetectable
5mvmE-3boeA:
undetectable		 5mvmA-3boeA:
18.03
5mvmE-3boeA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 3boe CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 10 ILE A 229
ALA A 232
LEU A 233
ILE A 412
ALA A 414
 None
 0.98A 5mvmD-3boeA:
undetectable
5mvmE-3boeA:
undetectable		 5mvmD-3boeA:
18.03
5mvmE-3boeA:
18.03