SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3boh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 CYH A  53
ASP A  55
HIS A 105
CYH A 115
GLY A 116
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.8A)
 0.26A 1ekjA-3bohA:
undetectable
1ekjB-3bohA:
undetectable		 1ekjA-3bohA:
24.42
1ekjB-3bohA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3001_0
(BETA-CARBONIC
ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 CYH A  53
ASP A  55
HIS A 105
CYH A 115
GLY A 116
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.8A)
 0.98A 1ekjA-3bohA:
undetectable
1ekjB-3bohA:
undetectable		 1ekjA-3bohA:
24.42
1ekjB-3bohA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 CYH A  53
ASP A  55
HIS A 105
CYH A 115
GLY A 116
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.8A)
 0.30A 1ekjA-3bohA:
undetectable
1ekjB-3bohA:
undetectable		 1ekjA-3bohA:
24.42
1ekjB-3bohA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_A_ACTA3003_0
(BETA-CARBONIC
ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 CYH A  53
VAL A  54
HIS A 105
CYH A 115
GLY A 116
 CD  A1001 ( 2.4A)
None
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.8A)
 1.40A 1ekjA-3bohA:
undetectable
1ekjB-3bohA:
undetectable		 1ekjA-3bohA:
24.42
1ekjB-3bohA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		4 / 7 CYH A  53
ASP A  55
HIS A 105
GLY A 116
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
ACT  A1002 (-3.8A)
 0.26A 1ekjE-3bohA:
undetectable
1ekjF-3bohA:
undetectable		 1ekjE-3bohA:
24.42
1ekjF-3bohA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_E_ACTE3005_0
(BETA-CARBONIC
ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		4 / 7 CYH A  53
ASP A  55
HIS A 105
GLY A 116
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
ACT  A1002 (-3.8A)
 0.93A 1ekjE-3bohA:
undetectable
1ekjF-3bohA:
undetectable		 1ekjE-3bohA:
24.42
1ekjF-3bohA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 CYH A  53
ASP A  55
HIS A 105
CYH A 115
GLY A 116
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.8A)
 0.30A 1ekjG-3bohA:
undetectable
1ekjH-3bohA:
undetectable		 1ekjG-3bohA:
24.42
1ekjH-3bohA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3002_0
(BETA-CARBONIC
ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 8 CYH A  53
ASP A  55
HIS A 105
CYH A 115
GLY A 116
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.8A)
 0.97A 1ekjG-3bohA:
undetectable
1ekjH-3bohA:
undetectable		 1ekjG-3bohA:
24.42
1ekjH-3bohA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		4 / 6 CYH A  53
ASP A  55
HIS A 105
CYH A 115
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
 0.28A 1ekjG-3bohA:
undetectable
1ekjH-3bohA:
undetectable		 1ekjG-3bohA:
24.42
1ekjH-3bohA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		4 / 6 CYH A  53
VAL A  54
HIS A 105
CYH A 115
 CD  A1001 ( 2.4A)
None
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
 1.40A 1ekjG-3bohA:
undetectable
1ekjH-3bohA:
undetectable		 1ekjG-3bohA:
24.42
1ekjH-3bohA:
24.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GXS_A_BEZA601_0
(P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
A
P-(S)-HYDROXYMANDELO
NITRILE LYASE CHAIN
B)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		4 / 7 GLY A  72
PRO A  70
HIS A  78
ALA A 203
 None
 0.95A 1gxsA-3bohA:
undetectable
1gxsB-3bohA:
undetectable		 1gxsA-3bohA:
21.56
1gxsB-3bohA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 GLY A 106
GLY A 114
GLY A 116
ASP A  55
HIS A 108
 None
None
ACT  A1002 (-3.8A)
ACT  A1002 ( 4.4A)
None
 1.10A 1wg8B-3bohA:
undetectable		 1wg8B-3bohA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		3 / 3 LEU A  85
PHE A 136
ARG A  80
 None
 0.80A 1xdkB-3bohA:
undetectable		 1xdkB-3bohA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_F_9CRF1600_2
(RETINOIC ACID
RECEPTOR, BETA)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		3 / 3 LEU A  85
PHE A 136
ARG A  80
 None
 0.80A 1xdkF-3bohA:
undetectable		 1xdkF-3bohA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		4 / 9 ILE A  73
ALA A 142
VAL A 145
GLU A 146
 None
 0.61A 2vufA-3bohA:
undetectable		 2vufA-3bohA:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 ILE A  73
GLY A  72
VAL A 104
ALA A  75
VAL A  95
 None
 0.88A 3fpjA-3bohA:
undetectable		 3fpjA-3bohA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 ILE A  73
GLY A  72
VAL A 104
ILE A  50
VAL A  95
 None
 0.89A 3fpjA-3bohA:
undetectable		 3fpjA-3bohA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 10 CYH A  53
ASP A  55
HIS A 105
CYH A 115
GLY A 116
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.8A)
 0.39A 3ucjA-3bohA:
undetectable		 3ucjA-3bohA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 10 CYH A  53
VAL A  54
HIS A 105
CYH A 115
GLY A 116
 CD  A1001 ( 2.4A)
None
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.8A)
 1.21A 3ucjA-3bohA:
undetectable		 3ucjA-3bohA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 10 CYH A  53
ASP A  55
HIS A 105
CYH A 115
GLY A 116
 CD  A1001 ( 2.4A)
ACT  A1002 ( 4.4A)
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.8A)
 0.41A 3ucjB-3bohA:
undetectable		 3ucjB-3bohA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 10 CYH A  53
VAL A  54
HIS A 105
CYH A 115
GLY A 116
 CD  A1001 ( 2.4A)
None
CD  A1001 (-3.5A)
CD  A1001 (-2.5A)
ACT  A1002 (-3.8A)
 1.22A 3ucjB-3bohA:
undetectable		 3ucjB-3bohA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 VAL A  54
LEU A 174
ILE A 166
VAL A 220
LEU A 168
 None
 1.06A 3w68A-3bohA:
undetectable		 3w68A-3bohA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 VAL A  54
LEU A 174
ILE A 166
VAL A 220
LEU A 168
 None
 1.05A 3w68D-3bohA:
undetectable		 3w68D-3bohA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 ILE A  32
GLN A  18
LEU A 201
PRO A 198
ILE A 219
 None
 1.02A 4m2xG-3bohA:
undetectable		 4m2xG-3bohA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_G_TMQG202_1
(DIHYDROFOLATE
REDUCTASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 ILE A  32
LEU A 201
PRO A 198
VAL A 197
ILE A 219
 None
 1.10A 4m2xG-3bohA:
undetectable		 4m2xG-3bohA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_A_SHHA404_1
(HISTONE DEACETYLASE
8)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 HIS A 159
GLY A 157
ASP A  55
HIS A 155
GLY A  56
 ACT  A1002 (-4.7A)
None
ACT  A1002 ( 4.4A)
None
None
 1.34A 4qa0A-3bohA:
undetectable		 4qa0A-3bohA:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_0
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 LEU A  14
ALA A 189
PHE A 193
GLY A 191
SER A  10
 None
 1.20A 5jglA-3bohA:
undetectable		 5jglA-3bohA:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3boh CADMIUM-SPECIFIC
CARBONIC ANHYDRASE
(Conticribra
weissflogii) 		5 / 12 LEU A  51
GLY A  49
THR A  62
ILE A  73
VAL A 145
 None
 1.00A 6emuA-3bohA:
undetectable		 6emuA-3bohA:
20.18