SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bol'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	13GS_A_SASA211_1 (GLUTATHIONE S-TRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 10	PRO A 277 VAL A 280 VAL A 49 ILE A 268 GLY A 20	None None None None K A 703 (-3.9A)	1.26A	13gsA-3bolA: undetectable	13gsA-3bolA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	13GS_B_SASB211_1 (GLUTATHIONE S-TRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 9	PRO A 277 VAL A 280 VAL A 49 ILE A 268 GLY A 20	None None None None K A 703 (-3.9A)	1.26A	13gsB-3bolA: undetectable	13gsB-3bolA: 18.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A7Y_A_DVAA2_0 (ACTINOMYCIN D)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 4	THR A 186 PRO A 306 THR A 184 PRO A 405	None	1.49A	1a7yA-3bolA: undetectable 1a7yC-3bolA: undetectable	1a7yA-3bolA: 2.60 1a7yC-3bolA: 2.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1Q8J_A_C2FA801_0 (5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	ARG A 321 ASP A 390 ASN A 411 ILE A 435 ASP A 473 GLY A 505 SER A 507	None	1.42A	1q8jA-3bolA: 61.2	1q8jA-3bolA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1Q8J_A_C2FA801_0 (5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	ASN A 323 ARG A 327 ASP A 358 ILE A 435 ASP A 473 GLY A 505	None	1.41A	1q8jA-3bolA: 61.2	1q8jA-3bolA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1Q8J_A_C2FA801_0 (5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	10 / 12	GLU A 320 ASN A 323 ARG A 327 ASP A 390 ASN A 411 ILE A 435 ASP A 473 GLY A 505 SER A 507 ILE A 536	None	0.23A	1q8jA-3bolA: 61.2	1q8jA-3bolA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1Q8J_B_C2FB802_0 (5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	10 / 12	GLU A 320 ASN A 323 GLY A 326 ASP A 390 ASN A 411 SER A 412 ILE A 435 GLY A 505 SER A 507 ILE A 536	None	0.44A	1q8jB-3bolA: 58.7	1q8jB-3bolA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1Q8J_B_C2FB802_0 (5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	GLY A 326 ASN A 411 SER A 412 ILE A 435 GLY A 505 SER A 507 ASN A 508	None	0.83A	1q8jB-3bolA: 58.7	1q8jB-3bolA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E7F_A_C2FA3000_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	ASN A 411 ILE A 435 LEU A 437 GLY A 505 SER A 507 ASN A 508	None	1.00A	2e7fA-3bolA: 26.4	2e7fA-3bolA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E7F_A_C2FA3000_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	8 / 12	GLU A 320 ASP A 390 ASN A 411 ILE A 435 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	0.66A	2e7fA-3bolA: 26.4	2e7fA-3bolA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E7F_B_C2FB4000_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	ASN A 411 ILE A 435 LEU A 437 GLY A 505 SER A 507 ASN A 508	None	0.98A	2e7fB-3bolA: 26.3	2e7fB-3bolA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E7F_B_C2FB4000_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	GLU A 320 ASN A 411 ILE A 435 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	0.67A	2e7fB-3bolA: 26.3	2e7fB-3bolA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OGY_A_C2FA3000_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	8 / 12	GLU A 320 ASP A 390 ASN A 411 ILE A 435 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	0.65A	2ogyA-3bolA: 26.3	2ogyA-3bolA: 16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OGY_B_C2FB4000_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	8 / 12	GLU A 320 ASP A 390 ASN A 411 ILE A 435 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	0.64A	2ogyB-3bolA: 26.2	2ogyB-3bolA: 16.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2V0M_D_KLND1499_1 (CYTOCHROME P450 3A4)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 5	PHE A 454 PHE A 301 SER A 534 ILE A 318	None	1.40A	2v0mD-3bolA: undetectable	2v0mD-3bolA: 24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YCJ_A_C2FA3000_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	ASN A 411 ILE A 435 LEU A 437 ASP A 473 GLY A 505 SER A 507 ASN A 508	None	0.87A	2ycjA-3bolA: 27.1	2ycjA-3bolA: 19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YCJ_A_C2FA3000_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	ASP A 358 ASN A 411 ILE A 435 ASP A 473 GLY A 505	None	1.24A	2ycjA-3bolA: 27.1	2ycjA-3bolA: 19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YCJ_A_C2FA3000_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	8 / 12	ASP A 390 ASN A 411 ILE A 435 LEU A 437 ASP A 473 GLY A 505 SER A 507 ILE A 536	None	0.61A	2ycjA-3bolA: 27.1	2ycjA-3bolA: 19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ADS_B_IMNB3_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	ILE A 367 ILE A 343 LEU A 379 LEU A 357 VAL A 359	None	1.30A	3adsB-3bolA: undetectable	3adsB-3bolA: 19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HEG_A_BAXA1_2 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 6	VAL A 102 ILE A 92 ILE A 61 LEU A 62	None None None K A 703 ( 4.9A)	0.76A	3hegA-3bolA: undetectable	3hegA-3bolA: 20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K13_A_THHA642_0 (5-METHYLTETRAHYDROFO LATE-HOMOCYSTEINE METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	GLU A 320 ASN A 323 ASP A 390 GLY A 505 SER A 507 ILE A 536	None	0.25A	3k13A-3bolA: 22.6	3k13A-3bolA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K13_B_THHB643_0 (5-METHYLTETRAHYDROFO LATE-HOMOCYSTEINE METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	GLU A 320 ASN A 323 ASP A 390 ASN A 411 GLY A 505 SER A 507 ILE A 536	None	0.33A	3k13B-3bolA: 22.6	3k13B-3bolA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3K13_C_THHC643_0 (5-METHYLTETRAHYDROFO LATE-HOMOCYSTEINE METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	GLU A 320 ASN A 323 ASP A 390 GLY A 505 SER A 507 ILE A 536	None	0.24A	3k13C-3bolA: 22.5	3k13C-3bolA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KO0_T_TFPT201_1 (PROTEIN S100-A4)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	PHE A 103 GLY A 271 PHE A 228 PHE A 169	None K A 703 (-4.8A) None None	1.04A	3ko0R-3bolA: undetectable 3ko0T-3bolA: undetectable	3ko0R-3bolA: 11.31 3ko0T-3bolA: 11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP3_B_AICB2002_1 (TRANSCRIPTIONAL REGULATOR TCAR)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	ALA A 403 ARG A 402 LYS A 429	None	0.84A	3kp3B-3bolA: undetectable	3kp3B-3bolA: 15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP5_B_KANB2002_1 (TRANSCRIPTIONAL REGULATOR TCAR)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	ALA A 403 ARG A 402 LYS A 429	None	1.11A	3kp5B-3bolA: undetectable	3kp5B-3bolA: 15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KP6_B_SALB3004_1 (TRANSCRIPTIONAL REGULATOR TCAR)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 5	ILE A 151 PHE A 195 ASP A 196 GLU A 197	None	1.07A	3kp6A-3bolA: undetectable 3kp6B-3bolA: undetectable	3kp6A-3bolA: 15.79 3kp6B-3bolA: 15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KU1_H_SAMH226_0 (SAM-DEPENDENT METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	LEU A 409 ASP A 473 VAL A 488 GLY A 531 LEU A 524 ILE A 528	None	1.47A	3ku1H-3bolA: 2.1	3ku1H-3bolA: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M6V_A_SAMA465_0 (RRNA METHYLASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	PRO A 211 GLY A 210 GLY A 236 VAL A 230 LEU A 62	None None None None K A 703 ( 4.9A)	1.05A	3m6vA-3bolA: undetectable	3m6vA-3bolA: 22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M6V_B_SAMB465_0 (RRNA METHYLASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	PRO A 211 GLY A 210 GLY A 236 VAL A 230 LEU A 62	None None None None K A 703 ( 4.9A)	1.04A	3m6vB-3bolA: undetectable	3m6vB-3bolA: 22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3M6W_A_SAMA465_0 (RRNA METHYLASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	PRO A 211 GLY A 210 GLY A 236 VAL A 230 VAL A 60 LEU A 62	None None None None None K A 703 ( 4.9A)	1.37A	3m6wA-3bolA: undetectable	3m6wA-3bolA: 22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P2K_A_SAMA6735_1 (16S RRNA METHYLASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	ASP A 358 GLU A 364 SER A 534	None	0.83A	3p2kA-3bolA: undetectable	3p2kA-3bolA: 18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PWW_A_ROCA1001_1 (ENDOTHIAPEPSIN)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	ASP A 19 GLY A 142 LEU A 18 PHE A 145 ILE A 106 THR A 63	K A 703 (-3.7A) None None None None None	1.27A	3pwwA-3bolA: undetectable	3pwwA-3bolA: 20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUE_D_SUED1201_2 (NS3 PROTEASE, NS4A PROTEIN)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	TYR A 31 LEU A 82 LYS A 81	None	0.78A	3sueD-3bolA: undetectable	3sueD-3bolA: 15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VNS_A_DVAA602_0 (NRPS ADENYLATION PROTEIN CYTC1)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	PHE A 466 ASP A 468 GLY A 432 PHE A 301	None	1.00A	3vnsA-3bolA: undetectable	3vnsA-3bolA: 23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W68_B_VIVB301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	ILE A 492 VAL A 310 ILE A 435 LEU A 409 VAL A 303	None	1.08A	3w68B-3bolA: undetectable	3w68B-3bolA: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W68_B_VIVB301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	ILE A 495 SER A 534 VAL A 310 ILE A 435 LEU A 409 VAL A 303	None	1.23A	3w68B-3bolA: undetectable	3w68B-3bolA: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W68_C_VIVC301_0 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	ILE A 495 VAL A 310 ILE A 435 LEU A 409 VAL A 303	None	1.04A	3w68C-3bolA: undetectable	3w68C-3bolA: 19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WRK_D_CAMD502_0 (CAMPHOR 5-MONOOXYGENASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 5	PHE A 283 LEU A 249 GLY A 210 VAL A 231	None	0.98A	3wrkD-3bolA: undetectable	3wrkD-3bolA: 23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WXO_A_NIZA804_1 (CATALASE-PEROXIDASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	ASN A 538 GLU A 320 ARG A 327	None	1.01A	3wxoA-3bolA: undetectable	3wxoA-3bolA: 23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DJE_A_C2FA300_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	8 / 12	GLU A 320 ASN A 323 ASP A 390 LEU A 437 ASP A 473 GLY A 505 SER A 507 ILE A 536	None	0.83A	4djeA-3bolA: 25.7	4djeA-3bolA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DJE_B_C2FB302_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	GLU A 320 ASP A 358 ASP A 390 ASN A 411 ASP A 473 GLY A 505 SER A 507	None	0.73A	4djeB-3bolA: 25.8	4djeB-3bolA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DJF_A_C2FA300_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	ASN A 323 ILE A 435 ASP A 473 GLY A 505 ASN A 508	None	0.93A	4djfA-3bolA: 25.8	4djfA-3bolA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DJF_A_C2FA300_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	GLU A 320 ASN A 323 ILE A 435 ASP A 473 GLY A 505 SER A 507 ILE A 536	None	0.37A	4djfA-3bolA: 25.8	4djfA-3bolA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DJF_B_C2FB300_0 (5-METHYLTETRAHYDROFO LATE CORRINOID/IRON SULFUR PROTEIN METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	8 / 12	GLU A 320 ASP A 358 ASP A 390 ASN A 411 ILE A 435 LEU A 437 GLY A 505 SER A 507	None	0.84A	4djfB-3bolA: 26.0	4djfB-3bolA: 16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J5J_B_478B401_2 (PROTEASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 10	ALA A 202 ILE A 268 GLY A 142 ILE A 143 VAL A 230	None	0.94A	4j5jB-3bolA: undetectable	4j5jB-3bolA: 10.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MBS_B_MRVB1101_2 (CHIMERA PROTEIN OF C-C CHEMOKINE RECEPTOR TYPE 5 AND RUBREDOXIN)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 5	TYR A 125 THR A 63 THR A 109 MET A 71	None	1.47A	4mbsB-3bolA: undetectable	4mbsB-3bolA: 21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_A_C2FA3000_0 (DIHYDROPTEROATE SYNTHASE DHPS)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	8 / 12	ASN A 323 ASP A 390 ILE A 435 LEU A 437 ASP A 473 GLY A 505 SER A 507 ILE A 536	None	1.15A	4o1eA-3bolA: 24.6	4o1eA-3bolA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_A_C2FA3000_0 (DIHYDROPTEROATE SYNTHASE DHPS)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	ASN A 360 ILE A 435 ASP A 473 GLY A 505 ILE A 536	None	0.83A	4o1eA-3bolA: 24.6	4o1eA-3bolA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_A_C2FA3000_0 (DIHYDROPTEROATE SYNTHASE DHPS)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	8 / 12	GLU A 320 ASN A 323 ASP A 390 ILE A 435 LEU A 437 ASP A 473 GLY A 505 ILE A 536	None	0.82A	4o1eA-3bolA: 24.6	4o1eA-3bolA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_B_C2FB4000_0 (DIHYDROPTEROATE SYNTHASE DHPS)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	ASN A 323 ASP A 390 ILE A 435 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	1.21A	4o1eB-3bolA: 24.4	4o1eB-3bolA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_B_C2FB4000_0 (DIHYDROPTEROATE SYNTHASE DHPS)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	ASP A 390 ILE A 435 LEU A 437 GLY A 505 ASN A 508 ILE A 536	None	0.98A	4o1eB-3bolA: 24.4	4o1eB-3bolA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O1E_B_C2FB4000_0 (DIHYDROPTEROATE SYNTHASE DHPS)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	GLU A 320 ASN A 323 ASP A 390 ILE A 435 LEU A 437 GLY A 505 ILE A 536	None	0.83A	4o1eB-3bolA: 24.4	4o1eB-3bolA: 21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q1Y_A_017A106_2 (ASPARTYL PROTEASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	ASP A 105 ILE A 171 ILE A 268 GLY A 270 ILE A 144	None	1.01A	4q1yB-3bolA: undetectable	4q1yB-3bolA: 10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4G_A_IPHA903_0 (PROTEIN ARGONAUTE-2)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 6	LEU A 479 LYS A 484 PRO A 485 GLU A 482	None	1.14A	4z4gA-3bolA: 2.6	4z4gA-3bolA: 20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_A_SORA1341_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	ARG A 402 ARG A 166 TYR A 125 TYR A 430	None	1.42A	5a06A-3bolA: undetectable	5a06A-3bolA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_C_SORC1341_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	ARG A 402 ARG A 166 TYR A 125 TYR A 430	None	1.39A	5a06C-3bolA: undetectable	5a06C-3bolA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_D_SORD1342_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	ARG A 402 ARG A 166 TYR A 125 TYR A 430	None	1.44A	5a06D-3bolA: 2.0	5a06D-3bolA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_E_SORE1342_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	ARG A 402 ARG A 166 TYR A 125 TYR A 430	None	1.41A	5a06E-3bolA: undetectable	5a06E-3bolA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_F_SORF1343_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	ARG A 402 ARG A 166 TYR A 125 TYR A 430	None	1.43A	5a06F-3bolA: 2.9	5a06F-3bolA: 20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOO_A_C2FA3001_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	GLU A 320 ASP A 358 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	0.75A	5vooA-3bolA: 22.6	5vooA-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOO_A_C2FA3001_1 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 5	ASN A 323 ASP A 390 ASN A 411 ASP A 473	None	0.37A	5vooA-3bolA: 22.6	5vooA-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOO_B_C2FB702_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	GLU A 320 ASN A 323 ASP A 358 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	0.74A	5vooB-3bolA: 22.5	5vooB-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOO_C_C2FC702_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	GLU A 320 ASP A 358 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	0.75A	5vooC-3bolA: 8.3	5vooC-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOO_C_C2FC702_1 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 5	ASN A 323 ASP A 390 ASN A 411 ASP A 473 ASN A 508	None	0.84A	5vooC-3bolA: 8.3	5vooC-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOO_D_C2FD3001_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	ASN A 360 ASP A 358 LEU A 437 GLY A 505 ILE A 536	None	1.15A	5vooD-3bolA: 22.5	5vooD-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOO_D_C2FD3001_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	GLU A 320 ASN A 323 ASP A 358 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	0.70A	5vooD-3bolA: 22.5	5vooD-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOO_E_C2FE3001_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	6 / 12	GLU A 320 ASP A 358 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	0.64A	5vooE-3bolA: 22.5	5vooE-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOO_E_C2FE3001_1 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 5	ASN A 323 ASP A 390 ASN A 411 ASP A 473 ASN A 508	None	0.89A	5vooE-3bolA: 22.5	5vooE-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOO_F_C2FF3001_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	GLU A 320 ASN A 323 ASP A 358 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	0.66A	5vooF-3bolA: 22.3	5vooF-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOP_A_C2FA3001_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	GLU A 320 ASN A 323 ASP A 358 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	0.66A	5vopA-3bolA: 23.0	5vopA-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOP_A_C2FA3001_1 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	ASP A 390 ASN A 411 ASP A 473	None	0.39A	5vopA-3bolA: 23.0	5vopA-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOP_B_C2FB3001_0 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	7 / 12	GLU A 320 ASN A 323 ASP A 358 LEU A 437 GLY A 505 SER A 507 ILE A 536	None	0.60A	5vopB-3bolA: 22.5	5vopB-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VOP_B_C2FB3001_1 (5-METHYLTETRAHYDROFO LATE HOMOCYSTEINE S-METHYLTRANSFERASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	3 / 3	ASP A 390 ASN A 411 ASP A 473	None	0.35A	5vopB-3bolA: 22.5	5vopB-3bolA: 19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YCP_A_BRLA501_0 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 12	PHE A 472 LEU A 409 ILE A 536 LEU A 461 LEU A 420	None	1.45A	5ycpA-3bolA: undetectable	5ycpA-3bolA: 8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A7J_A_TESA502_0 (CYTOCHROME P450)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 7	LEU A 154 ALA A 156 ALA A 157 THR A 69	None	0.70A	6a7jA-3bolA: undetectable	6a7jA-3bolA: 10.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AOG_A_CP6A704_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 10	VAL A 310 ASP A 313 HIS A 314 PHE A 312 VAL A 303	None	1.09A	6aogA-3bolA: undetectable	6aogA-3bolA: 9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AOG_B_CP6B704_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	5 / 10	VAL A 310 ASP A 313 HIS A 314 PHE A 312 VAL A 303	None	1.13A	6aogB-3bolA: undetectable	6aogB-3bolA: 9.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	3bol	5-METHYLTETRAHYDROFO LATE S-HOMOCYSTEINE METHYLTRANSFERASE (Thermotoga maritima)	4 / 5	ILE A 528 SER A 529 ALA A 522 LEU A 544	None	1.04A	6dwnA-3bolA: undetectable	6dwnA-3bolA: 9.74

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["13GS_A_SASA211_1","GLUTATHIONE S-TRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"PRO A 277;VAL A 280;VAL A  49;ILE A 268;GLY A  20","None;None;None;None;  K A 703 (-3.9A)","1.26A","13gsA-3bolA:undetectable","13gsA-3bolA:18.56"],["13GS_B_SASB211_1","GLUTATHIONE S-TRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"PRO A 277;VAL A 280;VAL A  49;ILE A 268;GLY A  20","None;None;None;None;  K A 703 (-3.9A)","1.26A","13gsB-3bolA:undetectable","13gsB-3bolA:18.56"],["1A7Y_A_DVAA2_0","ACTINOMYCIN D","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"THR A 186;PRO A 306;THR A 184;PRO A 405","None","1.49A","1a7yA-3bolA:undetectable;1a7yC-3bolA:undetectable","1a7yA-3bolA:2.60;1a7yC-3bolA:2.60"],["1Q8J_A_C2FA801_0","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"ARG A 321;ASP A 390;ASN A 411;ILE A 435;ASP A 473;GLY A 505;SER A 507","None","1.42A","1q8jA-3bolA:61.2","1q8jA-3bolA:100.00"],["1Q8J_A_C2FA801_0","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"ASN A 323;ARG A 327;ASP A 358;ILE A 435;ASP A 473;GLY A 505","None","1.41A","1q8jA-3bolA:61.2","1q8jA-3bolA:100.00"],["1Q8J_A_C2FA801_0","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",10,"GLU A 320;ASN A 323;ARG A 327;ASP A 390;ASN A 411;ILE A 435;ASP A 473;GLY A 505;SER A 507;ILE A 536","None","0.23A","1q8jA-3bolA:61.2","1q8jA-3bolA:100.00"],["1Q8J_B_C2FB802_0","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",10,"GLU A 320;ASN A 323;GLY A 326;ASP A 390;ASN A 411;SER A 412;ILE A 435;GLY A 505;SER A 507;ILE A 536","None","0.44A","1q8jB-3bolA:58.7","1q8jB-3bolA:100.00"],["1Q8J_B_C2FB802_0","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"GLY A 326;ASN A 411;SER A 412;ILE A 435;GLY A 505;SER A 507;ASN A 508","None","0.83A","1q8jB-3bolA:58.7","1q8jB-3bolA:100.00"],["2E7F_A_C2FA3000_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"ASN A 411;ILE A 435;LEU A 437;GLY A 505;SER A 507;ASN A 508","None","1.00A","2e7fA-3bolA:26.4","2e7fA-3bolA:16.75"],["2E7F_A_C2FA3000_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",8,"GLU A 320;ASP A 390;ASN A 411;ILE A 435;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","0.66A","2e7fA-3bolA:26.4","2e7fA-3bolA:16.75"],["2E7F_B_C2FB4000_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"ASN A 411;ILE A 435;LEU A 437;GLY A 505;SER A 507;ASN A 508","None","0.98A","2e7fB-3bolA:26.3","2e7fB-3bolA:16.75"],["2E7F_B_C2FB4000_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"GLU A 320;ASN A 411;ILE A 435;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","0.67A","2e7fB-3bolA:26.3","2e7fB-3bolA:16.75"],["2OGY_A_C2FA3000_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",8,"GLU A 320;ASP A 390;ASN A 411;ILE A 435;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","0.65A","2ogyA-3bolA:26.3","2ogyA-3bolA:16.58"],["2OGY_B_C2FB4000_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",8,"GLU A 320;ASP A 390;ASN A 411;ILE A 435;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","0.64A","2ogyB-3bolA:26.2","2ogyB-3bolA:16.58"],["2V0M_D_KLND1499_1","CYTOCHROME P450 3A4","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"PHE A 454;PHE A 301;SER A 534;ILE A 318","None","1.40A","2v0mD-3bolA:undetectable","2v0mD-3bolA:24.09"],["2YCJ_A_C2FA3000_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"ASN A 411;ILE A 435;LEU A 437;ASP A 473;GLY A 505;SER A 507;ASN A 508","None","0.87A","2ycjA-3bolA:27.1","2ycjA-3bolA:19.14"],["2YCJ_A_C2FA3000_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ASP A 358;ASN A 411;ILE A 435;ASP A 473;GLY A 505","None","1.24A","2ycjA-3bolA:27.1","2ycjA-3bolA:19.14"],["2YCJ_A_C2FA3000_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",8,"ASP A 390;ASN A 411;ILE A 435;LEU A 437;ASP A 473;GLY A 505;SER A 507;ILE A 536","None","0.61A","2ycjA-3bolA:27.1","2ycjA-3bolA:19.14"],["3ADS_B_IMNB3_1","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ILE A 367;ILE A 343;LEU A 379;LEU A 357;VAL A 359","None","1.30A","3adsB-3bolA:undetectable","3adsB-3bolA:19.26"],["3HEG_A_BAXA1_2","MITOGEN-ACTIVATED PROTEIN KINASE 14","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"VAL A 102;ILE A  92;ILE A  61;LEU A  62","None;None;None;  K A 703 ( 4.9A)","0.76A","3hegA-3bolA:undetectable","3hegA-3bolA:20.03"],["3K13_A_THHA642_0","5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"GLU A 320;ASN A 323;ASP A 390;GLY A 505;SER A 507;ILE A 536","None","0.25A","3k13A-3bolA:22.6","3k13A-3bolA:20.17"],["3K13_B_THHB643_0","5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"GLU A 320;ASN A 323;ASP A 390;ASN A 411;GLY A 505;SER A 507;ILE A 536","None","0.33A","3k13B-3bolA:22.6","3k13B-3bolA:20.17"],["3K13_C_THHC643_0","5-METHYLTETRAHYDROFOLATE-HOMOCYSTEINE METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"GLU A 320;ASN A 323;ASP A 390;GLY A 505;SER A 507;ILE A 536","None","0.24A","3k13C-3bolA:22.5","3k13C-3bolA:20.17"],["3KO0_T_TFPT201_1","PROTEIN S100-A4;PROTEIN S100-A4","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"PHE A 103;GLY A 271;PHE A 228;PHE A 169","None;  K A 703 (-4.8A);None;None","1.04A","3ko0R-3bolA:undetectable;3ko0T-3bolA:undetectable","3ko0R-3bolA:11.31;3ko0T-3bolA:11.31"],["3KP3_B_AICB2002_1","TRANSCRIPTIONAL REGULATOR TCAR","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"ALA A 403;ARG A 402;LYS A 429","None","0.84A","3kp3B-3bolA:undetectable","3kp3B-3bolA:15.79"],["3KP5_B_KANB2002_1","TRANSCRIPTIONAL REGULATOR TCAR","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"ALA A 403;ARG A 402;LYS A 429","None","1.11A","3kp5B-3bolA:undetectable","3kp5B-3bolA:15.79"],["3KP6_B_SALB3004_1","TRANSCRIPTIONAL REGULATOR TCAR;TRANSCRIPTIONAL REGULATOR TCAR","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"ILE A 151;PHE A 195;ASP A 196;GLU A 197","None","1.07A","3kp6A-3bolA:undetectable;3kp6B-3bolA:undetectable","3kp6A-3bolA:15.79;3kp6B-3bolA:15.79"],["3KU1_H_SAMH226_0","SAM-DEPENDENT METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"LEU A 409;ASP A 473;VAL A 488;GLY A 531;LEU A 524;ILE A 528","None","1.47A","3ku1H-3bolA:2.1","3ku1H-3bolA:20.45"],["3M6V_A_SAMA465_0","RRNA METHYLASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"PRO A 211;GLY A 210;GLY A 236;VAL A 230;LEU A  62","None;None;None;None;  K A 703 ( 4.9A)","1.05A","3m6vA-3bolA:undetectable","3m6vA-3bolA:22.88"],["3M6V_B_SAMB465_0","RRNA METHYLASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"PRO A 211;GLY A 210;GLY A 236;VAL A 230;LEU A  62","None;None;None;None;  K A 703 ( 4.9A)","1.04A","3m6vB-3bolA:undetectable","3m6vB-3bolA:22.88"],["3M6W_A_SAMA465_0","RRNA METHYLASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"PRO A 211;GLY A 210;GLY A 236;VAL A 230;VAL A  60;LEU A  62","None;None;None;None;None;  K A 703 ( 4.9A)","1.37A","3m6wA-3bolA:undetectable","3m6wA-3bolA:22.88"],["3P2K_A_SAMA6735_1","16S RRNA METHYLASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"ASP A 358;GLU A 364;SER A 534","None","0.83A","3p2kA-3bolA:undetectable","3p2kA-3bolA:18.49"],["3PWW_A_ROCA1001_1","ENDOTHIAPEPSIN","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"ASP A  19;GLY A 142;LEU A  18;PHE A 145;ILE A 106;THR A  63","  K A 703 (-3.7A);None;None;None;None;None","1.27A","3pwwA-3bolA:undetectable","3pwwA-3bolA:20.56"],["3SUE_D_SUED1201_2","NS3 PROTEASE, NS4A PROTEIN","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"TYR A  31;LEU A  82;LYS A  81","None","0.78A","3sueD-3bolA:undetectable","3sueD-3bolA:15.69"],["3VNS_A_DVAA602_0","NRPS ADENYLATION PROTEIN CYTC1","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"PHE A 466;ASP A 468;GLY A 432;PHE A 301","None","1.00A","3vnsA-3bolA:undetectable","3vnsA-3bolA:23.95"],["3W68_B_VIVB301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ILE A 492;VAL A 310;ILE A 435;LEU A 409;VAL A 303","None","1.08A","3w68B-3bolA:undetectable","3w68B-3bolA:19.07"],["3W68_B_VIVB301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"ILE A 495;SER A 534;VAL A 310;ILE A 435;LEU A 409;VAL A 303","None","1.23A","3w68B-3bolA:undetectable","3w68B-3bolA:19.07"],["3W68_C_VIVC301_0","ALPHA-TOCOPHEROL TRANSFER PROTEIN","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ILE A 495;VAL A 310;ILE A 435;LEU A 409;VAL A 303","None","1.04A","3w68C-3bolA:undetectable","3w68C-3bolA:19.07"],["3WRK_D_CAMD502_0","CAMPHOR 5-MONOOXYGENASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"PHE A 283;LEU A 249;GLY A 210;VAL A 231","None","0.98A","3wrkD-3bolA:undetectable","3wrkD-3bolA:23.46"],["3WXO_A_NIZA804_1","CATALASE-PEROXIDASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"ASN A 538;GLU A 320;ARG A 327","None","1.01A","3wxoA-3bolA:undetectable","3wxoA-3bolA:23.29"],["4DJE_A_C2FA300_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",8,"GLU A 320;ASN A 323;ASP A 390;LEU A 437;ASP A 473;GLY A 505;SER A 507;ILE A 536","None","0.83A","4djeA-3bolA:25.7","4djeA-3bolA:16.75"],["4DJE_B_C2FB302_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"GLU A 320;ASP A 358;ASP A 390;ASN A 411;ASP A 473;GLY A 505;SER A 507","None","0.73A","4djeB-3bolA:25.8","4djeB-3bolA:16.75"],["4DJF_A_C2FA300_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ASN A 323;ILE A 435;ASP A 473;GLY A 505;ASN A 508","None","0.93A","4djfA-3bolA:25.8","4djfA-3bolA:16.75"],["4DJF_A_C2FA300_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"GLU A 320;ASN A 323;ILE A 435;ASP A 473;GLY A 505;SER A 507;ILE A 536","None","0.37A","4djfA-3bolA:25.8","4djfA-3bolA:16.75"],["4DJF_B_C2FB300_0","5-METHYLTETRAHYDROFOLATE CORRINOID\/IRON SULFUR PROTEIN METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",8,"GLU A 320;ASP A 358;ASP A 390;ASN A 411;ILE A 435;LEU A 437;GLY A 505;SER A 507","None","0.84A","4djfB-3bolA:26.0","4djfB-3bolA:16.75"],["4J5J_B_478B401_2","PROTEASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ALA A 202;ILE A 268;GLY A 142;ILE A 143;VAL A 230","None","0.94A","4j5jB-3bolA:undetectable","4j5jB-3bolA:10.90"],["4MBS_B_MRVB1101_2","CHIMERA PROTEIN OF C-C CHEMOKINE RECEPTOR TYPE 5 AND RUBREDOXIN","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"TYR A 125;THR A  63;THR A 109;MET A  71","None","1.47A","4mbsB-3bolA:undetectable","4mbsB-3bolA:21.37"],["4O1E_A_C2FA3000_0","DIHYDROPTEROATE SYNTHASE DHPS","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",8,"ASN A 323;ASP A 390;ILE A 435;LEU A 437;ASP A 473;GLY A 505;SER A 507;ILE A 536","None","1.15A","4o1eA-3bolA:24.6","4o1eA-3bolA:21.95"],["4O1E_A_C2FA3000_0","DIHYDROPTEROATE SYNTHASE DHPS","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ASN A 360;ILE A 435;ASP A 473;GLY A 505;ILE A 536","None","0.83A","4o1eA-3bolA:24.6","4o1eA-3bolA:21.95"],["4O1E_A_C2FA3000_0","DIHYDROPTEROATE SYNTHASE DHPS","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",8,"GLU A 320;ASN A 323;ASP A 390;ILE A 435;LEU A 437;ASP A 473;GLY A 505;ILE A 536","None","0.82A","4o1eA-3bolA:24.6","4o1eA-3bolA:21.95"],["4O1E_B_C2FB4000_0","DIHYDROPTEROATE SYNTHASE DHPS","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"ASN A 323;ASP A 390;ILE A 435;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","1.21A","4o1eB-3bolA:24.4","4o1eB-3bolA:21.95"],["4O1E_B_C2FB4000_0","DIHYDROPTEROATE SYNTHASE DHPS","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"ASP A 390;ILE A 435;LEU A 437;GLY A 505;ASN A 508;ILE A 536","None","0.98A","4o1eB-3bolA:24.4","4o1eB-3bolA:21.95"],["4O1E_B_C2FB4000_0","DIHYDROPTEROATE SYNTHASE DHPS","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"GLU A 320;ASN A 323;ASP A 390;ILE A 435;LEU A 437;GLY A 505;ILE A 536","None","0.83A","4o1eB-3bolA:24.4","4o1eB-3bolA:21.95"],["4Q1Y_A_017A106_2","ASPARTYL PROTEASE;ASPARTYL PROTEASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ASP A 105;ILE A 171;ILE A 268;GLY A 270;ILE A 144","None","1.01A","4q1yB-3bolA:undetectable","4q1yB-3bolA:10.66"],["4Z4G_A_IPHA903_0","PROTEIN ARGONAUTE-2","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"LEU A 479;LYS A 484;PRO A 485;GLU A 482","None","1.14A","4z4gA-3bolA:2.6","4z4gA-3bolA:20.68"],["5A06_A_SORA1341_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"ARG A 402;ARG A 166;TYR A 125;TYR A 430","None","1.42A","5a06A-3bolA:undetectable","5a06A-3bolA:20.17"],["5A06_C_SORC1341_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"ARG A 402;ARG A 166;TYR A 125;TYR A 430","None","1.39A","5a06C-3bolA:undetectable","5a06C-3bolA:20.17"],["5A06_D_SORD1342_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"ARG A 402;ARG A 166;TYR A 125;TYR A 430","None","1.44A","5a06D-3bolA:2.0","5a06D-3bolA:20.17"],["5A06_E_SORE1342_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"ARG A 402;ARG A 166;TYR A 125;TYR A 430","None","1.41A","5a06E-3bolA:undetectable","5a06E-3bolA:20.17"],["5A06_F_SORF1343_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"ARG A 402;ARG A 166;TYR A 125;TYR A 430","None","1.43A","5a06F-3bolA:2.9","5a06F-3bolA:20.17"],["5VOO_A_C2FA3001_0","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"GLU A 320;ASP A 358;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","0.75A","5vooA-3bolA:22.6","5vooA-3bolA:19.93"],["5VOO_A_C2FA3001_1","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"ASN A 323;ASP A 390;ASN A 411;ASP A 473","None","0.37A","5vooA-3bolA:22.6","5vooA-3bolA:19.93"],["5VOO_B_C2FB702_0","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"GLU A 320;ASN A 323;ASP A 358;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","0.74A","5vooB-3bolA:22.5","5vooB-3bolA:19.93"],["5VOO_C_C2FC702_0","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"GLU A 320;ASP A 358;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","0.75A","5vooC-3bolA:8.3","5vooC-3bolA:19.93"],["5VOO_C_C2FC702_1","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ASN A 323;ASP A 390;ASN A 411;ASP A 473;ASN A 508","None","0.84A","5vooC-3bolA:8.3","5vooC-3bolA:19.93"],["5VOO_D_C2FD3001_0","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ASN A 360;ASP A 358;LEU A 437;GLY A 505;ILE A 536","None","1.15A","5vooD-3bolA:22.5","5vooD-3bolA:19.93"],["5VOO_D_C2FD3001_0","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"GLU A 320;ASN A 323;ASP A 358;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","0.70A","5vooD-3bolA:22.5","5vooD-3bolA:19.93"],["5VOO_E_C2FE3001_0","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",6,"GLU A 320;ASP A 358;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","0.64A","5vooE-3bolA:22.5","5vooE-3bolA:19.93"],["5VOO_E_C2FE3001_1","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"ASN A 323;ASP A 390;ASN A 411;ASP A 473;ASN A 508","None","0.89A","5vooE-3bolA:22.5","5vooE-3bolA:19.93"],["5VOO_F_C2FF3001_0","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"GLU A 320;ASN A 323;ASP A 358;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","0.66A","5vooF-3bolA:22.3","5vooF-3bolA:19.93"],["5VOP_A_C2FA3001_0","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"GLU A 320;ASN A 323;ASP A 358;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","0.66A","5vopA-3bolA:23.0","5vopA-3bolA:19.93"],["5VOP_A_C2FA3001_1","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"ASP A 390;ASN A 411;ASP A 473","None","0.39A","5vopA-3bolA:23.0","5vopA-3bolA:19.93"],["5VOP_B_C2FB3001_0","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",7,"GLU A 320;ASN A 323;ASP A 358;LEU A 437;GLY A 505;SER A 507;ILE A 536","None","0.60A","5vopB-3bolA:22.5","5vopB-3bolA:19.93"],["5VOP_B_C2FB3001_1","5-METHYLTETRAHYDROFOLATE HOMOCYSTEINE S-METHYLTRANSFERASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",3,"ASP A 390;ASN A 411;ASP A 473","None","0.35A","5vopB-3bolA:22.5","5vopB-3bolA:19.93"],["5YCP_A_BRLA501_0","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"PHE A 472;LEU A 409;ILE A 536;LEU A 461;LEU A 420","None","1.45A","5ycpA-3bolA:undetectable","5ycpA-3bolA:8.21"],["6A7J_A_TESA502_0","CYTOCHROME P450","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"LEU A 154;ALA A 156;ALA A 157;THR A  69","None","0.70A","6a7jA-3bolA:undetectable","6a7jA-3bolA:10.02"],["6AOG_A_CP6A704_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"VAL A 310;ASP A 313;HIS A 314;PHE A 312;VAL A 303","None","1.09A","6aogA-3bolA:undetectable","6aogA-3bolA:9.36"],["6AOG_B_CP6B704_0","BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLATE SYNTHASE","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",5,"VAL A 310;ASP A 313;HIS A 314;PHE A 312;VAL A 303","None","1.13A","6aogB-3bolA:undetectable","6aogB-3bolA:9.36"],["6DWN_A_AQ4A602_1","CYTOCHROME P450 1A1","3bol","5-METHYLTETRAHYDROFOLATE S-HOMOCYSTEINE METHYLTRANSFERASE","Thermotoga maritima",4,"ILE A 528;SER A 529;ALA A 522;LEU A 544","None","1.04A","6dwnA-3bolA:undetectable","6dwnA-3bolA:9.74"]]