SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bop'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 3bop BETA-NEUREXIN 2D4
(Mus
musculus) 		5 / 12 LEU A 241
GLY A  95
GLY A  92
ILE A  98
LEU A 115
 None
 1.12A 1p91B-3bopA:
undetectable		 1p91B-3bopA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 3bop BETA-NEUREXIN 2D4
(Mus
musculus) 		5 / 12 GLY A 185
GLY A 184
ILE A 153
ASP A 160
GLY A 151
 None
 0.96A 1sqfA-3bopA:
undetectable		 1sqfA-3bopA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 3bop BETA-NEUREXIN 2D4
(Mus
musculus) 		4 / 6 ASP A 160
SER A 133
LEU A 137
GLY A 138
 None
 0.96A 2j2pA-3bopA:
undetectable
2j2pC-3bopA:
undetectable		 2j2pA-3bopA:
22.67
2j2pC-3bopA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 3bop BETA-NEUREXIN 2D4
(Mus
musculus) 		4 / 6 ASP A 160
SER A 133
LEU A 137
GLY A 138
 None
 0.96A 2j2pD-3bopA:
undetectable
2j2pF-3bopA:
undetectable		 2j2pD-3bopA:
22.67
2j2pF-3bopA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 3bop BETA-NEUREXIN 2D4
(Mus
musculus) 		4 / 4 ALA A 244
VAL A 240
GLY A 232
THR A  87
 None
 1.11A 4ubeA-3bopA:
undetectable		 4ubeA-3bopA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3bop BETA-NEUREXIN 2D4
(Mus
musculus) 		4 / 7 ILE A 217
LEU A 233
ARG A 252
THR A 101
 None
 0.92A 5b3sA-3bopA:
undetectable
5b3sJ-3bopA:
undetectable		 5b3sA-3bopA:
15.56
5b3sJ-3bopA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3bop BETA-NEUREXIN 2D4
(Mus
musculus) 		4 / 4 SER A 125
ALA A 126
GLN A 227
THR A 121
 None
 1.47A 5n0rA-3bopA:
undetectable		 5n0rA-3bopA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3bop BETA-NEUREXIN 2D4
(Mus
musculus) 		4 / 4 SER A 125
ALA A 126
GLN A 227
THR A 121
 None
 1.43A 5n0sA-3bopA:
undetectable		 5n0sA-3bopA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3bop BETA-NEUREXIN 2D4
(Mus
musculus) 		4 / 4 SER A 125
ALA A 126
GLN A 227
THR A 121
 None
 1.45A 5n0wA-3bopA:
undetectable		 5n0wA-3bopA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 3bop BETA-NEUREXIN 2D4
(Mus
musculus) 		4 / 4 SER A 125
ALA A 126
GLN A 227
THR A 121
 None
 1.45A 5n0xA-3bopA:
undetectable		 5n0xA-3bopA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3bop BETA-NEUREXIN 2D4
(Mus
musculus) 		4 / 7 ILE A 217
LEU A 233
ARG A 252
THR A 101
 None
 0.92A 5zcqA-3bopA:
undetectable
5zcqJ-3bopA:
undetectable		 5zcqA-3bopA:
15.56
5zcqJ-3bopA:
18.45