SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bpo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CQP_B_803B311_1 (ANTIGEN CD11A (P180))	3bpo	INTERLEUKIN 13 (Homo sapiens)	4 / 7	VAL A 34 LEU A 28 LEU A 67 LEU A 51	VAL A 34 ( 0.6A) LEU A 28 ( 0.6A) LEU A 67 ( 0.6A) LEU A 51 ( 0.6A)	0.82A	1cqpA-3bpoA: undetectable 1cqpB-3bpoA: undetectable	1cqpA-3bpoA: 21.62 1cqpB-3bpoA: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_B_9CRB600_2 (RETINOIC ACID RECEPTOR, BETA)	3bpo	INTERLEUKIN-13 RECEPTOR ALPHA-1 CHAIN (Homo sapiens)	3 / 3	LEU C 258 PHE C 253 ARG C 225	LEU C 258 ( 0.5A) PHE C 253 ( 1.3A) ARG C 225 ( 0.6A)	0.76A	1xdkB-3bpoC: undetectable	1xdkB-3bpoC: 19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_F_9CRF1600_2 (RETINOIC ACID RECEPTOR, BETA)	3bpo	INTERLEUKIN-13 RECEPTOR ALPHA-1 CHAIN (Homo sapiens)	3 / 3	LEU C 258 PHE C 253 ARG C 225	LEU C 258 ( 0.5A) PHE C 253 ( 1.3A) ARG C 225 ( 0.6A)	0.76A	1xdkF-3bpoC: undetectable	1xdkF-3bpoC: 19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA152_0 (ILEAL BILE ACID-BINDING PROTEIN)	3bpo	INTERLEUKIN 13 (Homo sapiens)	3 / 3	VAL A 34 LYS A 89 HIS A 84	VAL A 34 ( 0.6A) LYS A 89 ( 0.0A) HIS A 84 ( 1.0A)	0.94A	3elzA-3bpoA: undetectable	3elzA-3bpoA: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KK6_A_CELA701_1 (PROSTAGLANDIN G/H SYNTHASE 1)	3bpo	INTERLEUKIN 13 (Homo sapiens)	5 / 12	LEU A 103 SER A 50 ILE A 37 GLY A 42 ALA A 41	LEU A 103 ( 0.6A) SER A 50 ( 0.0A) ILE A 37 ( 0.4A) GLY A 42 ( 0.0A) ALA A 41 ( 0.0A)	1.07A	3kk6A-3bpoA: undetectable	3kk6A-3bpoA: 11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G5J_A_0WMA1102_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	3bpo	INTERLEUKIN-13 RECEPTOR ALPHA-1 CHAIN (Homo sapiens)	4 / 7	PHE C 183 TYR C 158 ILE C 213 PRO C 148	PHE C 183 ( 1.3A) TYR C 158 ( 1.3A) ILE C 213 ( 0.6A) PRO C 148 ( 1.1A)	0.78A	4g5jA-3bpoC: undetectable	4g5jA-3bpoC: 20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LG3_I_Z80I401_1 (GAMMA-AMINOBUTYRIC-A CID RECEPTOR SUBUNIT BETA-1)	3bpo	INTERLEUKIN 13 INTERLEUKIN-13 RECEPTOR ALPHA-1 CHAIN (Homo sapiens)	4 / 9	ILE C 78 ASP A 87 TRP A 35 ILE A 90	ILE C 78 ( 0.7A) ASP A 87 ( 0.6A) TRP A 35 ( 0.5A) ILE A 90 ( 0.7A)	1.05A	5lg3I-3bpoC: 2.5	5lg3I-3bpoC: 21.22

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CQP_B_803B311_1","ANTIGEN CD11A (P180);ANTIGEN CD11A (P180)","3bpo","INTERLEUKIN 13","Homo sapiens",4,"VAL A  34;LEU A  28;LEU A  67;LEU A  51","VAL A  34 ( 0.6A);LEU A  28 ( 0.6A);LEU A  67 ( 0.6A);LEU A  51 ( 0.6A)","0.82A","1cqpA-3bpoA:undetectable;1cqpB-3bpoA:undetectable","1cqpA-3bpoA:21.62;1cqpB-3bpoA:21.62"],["1XDK_B_9CRB600_2","RETINOIC ACID RECEPTOR, BETA","3bpo","INTERLEUKIN-13 RECEPTOR ALPHA-1 CHAIN","Homo sapiens",3,"LEU C 258;PHE C 253;ARG C 225","LEU C 258 ( 0.5A);PHE C 253 ( 1.3A);ARG C 225 ( 0.6A)","0.76A","1xdkB-3bpoC:undetectable","1xdkB-3bpoC:19.94"],["1XDK_F_9CRF1600_2","RETINOIC ACID RECEPTOR, BETA","3bpo","INTERLEUKIN-13 RECEPTOR ALPHA-1 CHAIN","Homo sapiens",3,"LEU C 258;PHE C 253;ARG C 225","LEU C 258 ( 0.5A);PHE C 253 ( 1.3A);ARG C 225 ( 0.6A)","0.76A","1xdkF-3bpoC:undetectable","1xdkF-3bpoC:19.94"],["3ELZ_A_CHDA152_0","ILEAL BILE ACID-BINDING PROTEIN","3bpo","INTERLEUKIN 13","Homo sapiens",3,"VAL A  34;LYS A  89;HIS A  84","VAL A  34 ( 0.6A);LYS A  89 ( 0.0A);HIS A  84 ( 1.0A)","0.94A","3elzA-3bpoA:undetectable","3elzA-3bpoA:19.05"],["3KK6_A_CELA701_1","PROSTAGLANDIN G\/H SYNTHASE 1","3bpo","INTERLEUKIN 13","Homo sapiens",5,"LEU A 103;SER A  50;ILE A  37;GLY A  42;ALA A  41","LEU A 103 ( 0.6A);SER A  50 ( 0.0A);ILE A  37 ( 0.4A);GLY A  42 ( 0.0A);ALA A  41 ( 0.0A)","1.07A","3kk6A-3bpoA:undetectable","3kk6A-3bpoA:11.83"],["4G5J_A_0WMA1102_1","EPIDERMAL GROWTH FACTOR RECEPTOR","3bpo","INTERLEUKIN-13 RECEPTOR ALPHA-1 CHAIN","Homo sapiens",4,"PHE C 183;TYR C 158;ILE C 213;PRO C 148","PHE C 183 ( 1.3A);TYR C 158 ( 1.3A);ILE C 213 ( 0.6A);PRO C 148 ( 1.1A)","0.78A","4g5jA-3bpoC:undetectable","4g5jA-3bpoC:20.45"],["5LG3_I_Z80I401_1","GAMMA-AMINOBUTYRIC-ACID RECEPTOR SUBUNIT BETA-1","3bpo","INTERLEUKIN 13;INTERLEUKIN-13 RECEPTOR ALPHA-1 CHAIN","Homo sapiens",4,"ILE C  78;ASP A  87;TRP A  35;ILE A  90","ILE C  78 ( 0.7A);ASP A  87 ( 0.6A);TRP A  35 ( 0.5A);ILE A  90 ( 0.7A)","1.05A","5lg3I-3bpoC:2.5","5lg3I-3bpoC:21.22"]]