SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bpq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GP0_A_NILA1_2 (MITOGEN-ACTIVATED PROTEIN KINASE 11)	3bpq	TOXIN RELE3 (Methanocaldococc us jannaschii)	4 / 7	ARG B 23 VAL B 3 LEU B 13 ILE B 72	None	0.83A	3gp0A-3bpqB: undetectable	3gp0A-3bpqB: 14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MDT_A_VORA506_1 (CHOLESTEROL 24-HYDROXYLASE)	3bpq	ANTITOXIN RELB3 TOXIN RELE3 (Methanocaldococc us jannaschii)	5 / 9	SER B 62 ALA A 31 THR A 35 ALA B 6 THR B 8	None	1.25A	3mdtA-3bpqB: undetectable	3mdtA-3bpqB: 13.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FXS_A_MOAA702_1 (INOSINE-5'-MONOPHOSP HATE DEHYDROGENASE)	3bpq	TOXIN RELE3 (Methanocaldococc us jannaschii)	5 / 9	SER B 34 SER B 36 ASN B 35 ILE B 72 ASP B 70	None	1.32A	4fxsA-3bpqB: undetectable	4fxsA-3bpqB: 10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WM7_A_ACTA603_0 (SALICYLATE-AMP LIGASE)	3bpq	ANTITOXIN RELB3 TOXIN RELE3 (Methanocaldococc us jannaschii; Methanocaldococc us jannaschii)	4 / 4	THR A 35 THR B 8 ALA B 6 ARG B 76	None	1.28A	5wm7A-3bpqA: undetectable	5wm7A-3bpqA: 6.97

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3GP0_A_NILA1_2","MITOGEN-ACTIVATED PROTEIN KINASE 11","3bpq","TOXIN RELE3","Methanocaldococcus jannaschii",4,"ARG B  23;VAL B   3;LEU B  13;ILE B  72","None","0.83A","3gp0A-3bpqB:undetectable","3gp0A-3bpqB:14.41"],["3MDT_A_VORA506_1","CHOLESTEROL 24-HYDROXYLASE","3bpq","ANTITOXIN RELB3;TOXIN RELE3","Methanocaldococcus jannaschii",5,"SER B  62;ALA A  31;THR A  35;ALA B   6;THR B   8","None","1.25A","3mdtA-3bpqB:undetectable","3mdtA-3bpqB:13.12"],["4FXS_A_MOAA702_1","INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE","3bpq","TOXIN RELE3","Methanocaldococcus jannaschii",5,"SER B  34;SER B  36;ASN B  35;ILE B  72;ASP B  70","None","1.32A","4fxsA-3bpqB:undetectable","4fxsA-3bpqB:10.46"],["5WM7_A_ACTA603_0","SALICYLATE-AMP LIGASE","3bpq","ANTITOXIN RELB3;TOXIN RELE3","Methanocaldococcus jannaschii;Methanocaldococcus jannaschii",4,"THR A  35;THR B   8;ALA B   6;ARG B  76","None","1.28A","5wm7A-3bpqA:undetectable","5wm7A-3bpqA:6.97"]]