SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bpv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_D_DESD600_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 LEU A  71
LEU A 103
VAL A 107
LEU A  40
ILE A  77
 None
 1.00A 1s9pD-3bpvA:
undetectable		 1s9pD-3bpvA:
18.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		6 / 8 ALA A  34
CYH A  38
PHE A  57
THR A  63
ILE A  64
THR A  67
 None
 0.51A 3bpxA-3bpvA:
21.7
3bpxB-3bpvA:
21.5		 3bpxA-3bpvA:
100.00
3bpxB-3bpvA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3BPX_B_SALB258_1
(TRANSCRIPTIONAL
REGULATOR)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		6 / 11 ILE A   5
PRO A   6
LYS A   8
GLY A   9
SER A  12
ARG A  16
 None
 0.45A 3bpxA-3bpvA:
21.7
3bpxB-3bpvA:
21.5		 3bpxA-3bpvA:
100.00
3bpxB-3bpvA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		5 / 12 PHE A  21
ILE A  22
ILE A  14
VAL A  36
ARG A 110
 None
 1.08A 3fpjB-3bpvA:
undetectable		 3fpjB-3bpvA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XR4_B_AG2B511_1
(HOMOSPERMIDINE
SYNTHASE)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 VAL A 139
PHE A  56
ARG A  44
 None
 0.69A 4xr4B-3bpvA:
undetectable		 4xr4B-3bpvA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		3 / 3 LEU A  15
ARG A  16
ARG A  19
 None
 0.95A 4yiaB-3bpvA:
undetectable		 4yiaB-3bpvA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 GLU A  45
GLU A  92
THR A  94
LEU A  39
 None
 1.23A 5hm8A-3bpvA:
undetectable		 5hm8A-3bpvA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 GLU A  45
GLU A  92
THR A  94
LEU A  39
 None
 1.23A 5hm8B-3bpvA:
undetectable		 5hm8B-3bpvA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 GLU A  45
GLU A  92
THR A  94
LEU A  39
 None
 1.23A 5hm8C-3bpvA:
undetectable		 5hm8C-3bpvA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 GLU A  45
GLU A  92
THR A  94
LEU A  39
 None
 1.23A 5hm8D-3bpvA:
undetectable		 5hm8D-3bpvA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 GLU A  45
GLU A  92
THR A  94
LEU A  39
 None
 1.23A 5hm8E-3bpvA:
undetectable		 5hm8E-3bpvA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 GLU A  45
GLU A  92
THR A  94
LEU A  39
 None
 1.22A 5hm8F-3bpvA:
undetectable		 5hm8F-3bpvA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bpv TRANSCRIPTIONAL
REGULATOR
(Methanothermobac
ter
thermautotrophic
us) 		4 / 5 GLU A  45
GLU A  92
THR A  94
LEU A  39
 None
 1.22A 5hm8H-3bpvA:
undetectable		 5hm8H-3bpvA:
13.27