SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bqh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 3bqh PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB
(Neisseria
meningitidis) 		5 / 11 LEU A 309
ARG A 311
ILE A 305
LEU A 263
ASP A 264
 None
 1.25A 2q6hA-3bqhA:
undetectable		 2q6hA-3bqhA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 3bqh PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB
(Neisseria
meningitidis) 		5 / 11 LEU A 309
ARG A 311
ILE A 305
LEU A 263
ASP A 264
 None
 1.26A 2qeiA-3bqhA:
undetectable		 2qeiA-3bqhA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 3bqh PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB
(Neisseria
meningitidis) 		4 / 6 ILE A 305
LEU A 309
LEU A 263
ASP A 264
 None
 0.95A 2rlfA-3bqhA:
undetectable
2rlfD-3bqhA:
undetectable		 2rlfA-3bqhA:
12.17
2rlfD-3bqhA:
12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3bqh PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB
(Neisseria
meningitidis) 		4 / 7 GLU A 250
ARG A 291
GLY A 231
LYS A 328
 None
 1.04A 4fgzA-3bqhA:
undetectable		 4fgzA-3bqhA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 3bqh PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB
(Neisseria
meningitidis) 		4 / 6 GLU A 335
GLN A 338
VAL A 252
THR A 251
 None
ACT  A1000 (-3.6A)
None
None
 1.28A 4lnxA-3bqhA:
undetectable		 4lnxA-3bqhA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 3bqh PEPTIDE METHIONINE
SULFOXIDE REDUCTASE
MSRA/MSRB
(Neisseria
meningitidis) 		3 / 5 GLY A 210
GLY A 206
GLU A 250
 None
 0.49A 4z2eA-3bqhA:
undetectable
4z2eD-3bqhA:
undetectable		 4z2eA-3bqhA:
17.78
4z2eD-3bqhA:
19.29