SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bql'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_A_ADNA601_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3bql ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 5 THR A1269
GLU A1307
THR A1308
HIS A1315
 None
 1.42A 1d4fA-3bqlA:
undetectable		 1d4fA-3bqlA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 3bql ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 5 THR A1269
GLU A1307
THR A1308
HIS A1315
 None
 1.40A 1d4fB-3bqlA:
undetectable		 1d4fB-3bqlA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_1
(HISTONE
METHYLTRANSFERASE
DOT1L)		 3bql ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 4 THR A1269
GLN A1270
GLU A1518
ASP A1520
 None
 1.35A 1nw3A-3bqlA:
0.0		 1nw3A-3bqlA:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 3bql ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		3 / 3 GLU A1456
TRP A1249
LYS A1422
 None
 1.33A 1qu2A-3bqlA:
undetectable		 1qu2A-3bqlA:
16.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GLQ_A_RABA602_2
(ADENOSYLHOMOCYSTEINA
SE)		 3bql ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 5 GLN A1270
THR A1269
GLU A1307
HIS A1315
 None
 1.39A 3glqA-3bqlA:
undetectable		 3glqA-3bqlA:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA609_0
(ACETYLCHOLINESTERASE)		 3bql ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		4 / 6 TYR A1530
TYR A1526
ASP A1259
HIS A1257
 None
 1.39A 5ov9A-3bqlA:
undetectable		 5ov9A-3bqlA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NJ9_K_SAMK500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 3bql ERYTHROCYTE MEMBRANE
PROTEIN 1
(Plasmodium
falciparum) 		3 / 3 THR A1234
GLU A1456
ASN A1271
 None
 0.83A 6nj9K-3bqlA:
undetectable		 6nj9K-3bqlA:
22.69