SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bqx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 3bqx GLYOXALASE-RELATED
ENZYME
(Fulvimarina
pelagi) 		5 / 9 LEU A  86
GLY A 111
ALA A 101
ASP A 102
GLY A 108
 None
 1.04A 3ektA-3bqxA:
undetectable		 3ektA-3bqxA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 3bqx GLYOXALASE-RELATED
ENZYME
(Fulvimarina
pelagi) 		4 / 4 ARG A  89
ASP A 102
GLY A 108
THR A  81
 None
 1.40A 3k4vB-3bqxA:
undetectable		 3k4vB-3bqxA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 3bqx GLYOXALASE-RELATED
ENZYME
(Fulvimarina
pelagi) 		3 / 3 THR A  65
SER A  66
ARG A  67
 None
 0.72A 3phnA-3bqxA:
undetectable		 3phnA-3bqxA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 3bqx GLYOXALASE-RELATED
ENZYME
(Fulvimarina
pelagi) 		3 / 3 LEU A  16
GLU A  17
SER A  19
 None
 0.72A 4ccqA-3bqxA:
undetectable		 4ccqA-3bqxA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OH1_C_9UQC202_0
(CEREBLON ISOFORM 4)		 3bqx GLYOXALASE-RELATED
ENZYME
(Fulvimarina
pelagi) 		4 / 8 ASN A 126
PRO A 127
GLU A  80
PHE A 125
 None
 1.34A 5oh1C-3bqxA:
undetectable		 5oh1C-3bqxA:
21.85