SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3br8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA153_1
(CALMODULIN)		 3br8 PROBABLE
ACYLPHOSPHATASE
(Bacillus
subtilis) 		4 / 8 ILE A  88
MET A  23
GLU A  24
VAL A  34
 None
 0.73A 1a29A-3br8A:
undetectable		 1a29A-3br8A:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3br8 PROBABLE
ACYLPHOSPHATASE
(Bacillus
subtilis) 		5 / 12 ALA A  31
GLY A  48
GLY A  82
MET A   1
ALA A  25
 None
 1.16A 3ou6B-3br8A:
undetectable		 3ou6B-3br8A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3br8 PROBABLE
ACYLPHOSPHATASE
(Bacillus
subtilis) 		5 / 12 ALA A  31
GLY A  48
GLY A  82
MET A   1
ALA A  25
 None
 1.17A 3ou7B-3br8A:
undetectable		 3ou7B-3br8A:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3br8 PROBABLE
ACYLPHOSPHATASE
(Bacillus
subtilis) 		5 / 11 GLY A  63
VAL A  60
GLU A  24
SER A  64
VAL A  69
 None
 1.23A 4danA-3br8A:
undetectable		 4danA-3br8A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3br8 PROBABLE
ACYLPHOSPHATASE
(Bacillus
subtilis) 		5 / 12 GLY A  63
VAL A  60
GLU A  24
SER A  64
VAL A  69
 None
 1.19A 4danA-3br8A:
undetectable
4danB-3br8A:
undetectable		 4danA-3br8A:
17.65
4danB-3br8A:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 3br8 PROBABLE
ACYLPHOSPHATASE
(Bacillus
subtilis) 		4 / 5 LEU A  30
ALA A  59
VAL A  74
ILE A  72
 None
 0.95A 4xe3A-3br8A:
undetectable		 4xe3A-3br8A:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_B_CL6B502_1
(CYTOCHROME P-450)		 3br8 PROBABLE
ACYLPHOSPHATASE
(Bacillus
subtilis) 		4 / 5 LEU A  30
ALA A  59
VAL A  74
ILE A  72
 None
 0.90A 4xe3B-3br8A:
undetectable		 4xe3B-3br8A:
12.25