SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bry'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_A_NIOA604_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 5 SER A 399
THR A 381
GLU A   7
GLY A   8
 None
 0.91A 1icrA-3bryA:
undetectable
1icrB-3bryA:
undetectable		 1icrA-3bryA:
20.00
1icrB-3bryA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICR_B_NIOB602_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 5 GLU A   7
GLY A   8
SER A 399
THR A 381
 None
 0.88A 1icrA-3bryA:
undetectable
1icrB-3bryA:
undetectable		 1icrA-3bryA:
20.00
1icrB-3bryA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_A_NIOA221_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 6 SER A 399
THR A 381
GLU A   7
GLY A   8
 None
 0.91A 1icuA-3bryA:
undetectable
1icuB-3bryA:
undetectable		 1icuA-3bryA:
20.00
1icuB-3bryA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_B_NIOB219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 6 GLU A   7
GLY A   8
SER A 399
THR A 381
 None
 0.89A 1icuA-3bryA:
undetectable
1icuB-3bryA:
undetectable		 1icuA-3bryA:
20.00
1icuB-3bryA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICU_C_NIOC225_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 6 SER A 399
THR A 381
GLU A   7
GLY A   8
 None
 0.95A 1icuC-3bryA:
undetectable
1icuD-3bryA:
undetectable		 1icuC-3bryA:
20.00
1icuD-3bryA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_C_NIOC708_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 5 SER A 399
THR A 381
GLU A   7
GLY A   8
 None
 0.90A 1icvC-3bryA:
undetectable
1icvD-3bryA:
undetectable		 1icvC-3bryA:
20.00
1icvD-3bryA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 5 GLU A   7
GLY A   8
SER A 399
THR A 381
 None
 0.90A 1icvC-3bryA:
undetectable
1icvD-3bryA:
undetectable		 1icvC-3bryA:
20.00
1icvD-3bryA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KF6_B_ACTB704_0
(FUMARATE REDUCTASE
FLAVOPROTEIN
FUMARATE REDUCTASE
IRON-SULFUR PROTEIN)		 3bry TBUX
(Ralstonia
pickettii) 		3 / 3 ARG A 222
GLY A 220
ASP A 157
 None
 0.59A 1kf6A-3bryA:
undetectable
1kf6B-3bryA:
undetectable		 1kf6A-3bryA:
21.42
1kf6B-3bryA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_A_BEZA524_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 6 SER A 399
THR A 381
GLU A   7
GLY A   8
 None
 0.92A 1kqbA-3bryA:
undetectable
1kqbB-3bryA:
undetectable		 1kqbA-3bryA:
20.40
1kqbB-3bryA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 5 GLU A   7
GLY A   8
SER A 399
THR A 381
 None
 0.91A 1kqbA-3bryA:
undetectable
1kqbB-3bryA:
undetectable		 1kqbA-3bryA:
20.40
1kqbB-3bryA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_C_BEZC522_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 6 SER A 399
THR A 381
GLU A   7
GLY A   8
 None
 0.89A 1kqbC-3bryA:
undetectable
1kqbD-3bryA:
undetectable		 1kqbC-3bryA:
20.40
1kqbD-3bryA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_D_BEZD523_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 6 GLU A   7
GLY A   8
SER A 399
THR A 381
 None
 0.90A 1kqbC-3bryA:
undetectable
1kqbD-3bryA:
undetectable		 1kqbC-3bryA:
20.40
1kqbD-3bryA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N2X_A_SAMA401_0
(S-ADENOSYL-METHYLTRA
NSFERASE MRAW)		 3bry TBUX
(Ralstonia
pickettii) 		5 / 12 HIS A 244
GLY A 218
GLY A 246
VAL A 138
ASP A 157
 None
 1.21A 1n2xA-3bryA:
undetectable		 1n2xA-3bryA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZZ_A_ACTA421_0
(ACLACINOMYCIN-10-HYD
ROXYLASE)		 3bry TBUX
(Ralstonia
pickettii) 		5 / 8 ASP A 298
GLY A  20
GLY A  18
GLY A  17
SER A 296
 None
 1.14A 1qzzA-3bryA:
undetectable		 1qzzA-3bryA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 8 GLN A 240
VAL A 159
VAL A   3
VAL A 307
 None
 0.77A 2bdmA-3bryA:
undetectable		 2bdmA-3bryA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 5 SER A  13
GLY A  17
ASP A 334
ASP A 298
 None
 1.07A 2oxtB-3bryA:
undetectable		 2oxtB-3bryA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3V_A_TOPA1169_1
(DIHYDROFOLATE
REDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		5 / 12 VAL A 159
TRP A 217
ALA A 216
ILE A 219
THR A 161
 None
 0.97A 2w3vA-3bryA:
undetectable		 2w3vA-3bryA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_D_SALD1300_1
(LYSR-TYPE REGULATORY
PROTEIN)		 3bry TBUX
(Ralstonia
pickettii) 		5 / 12 THR A  55
ILE A  57
GLY A  71
GLY A 107
LEU A 106
 None
 1.22A 2y7kD-3bryA:
undetectable		 2y7kD-3bryA:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 3bry TBUX
(Ralstonia
pickettii) 		5 / 12 LEU A 169
LEU A 168
GLN A 129
LEU A 165
LEU A 328
 None
None
None
None
C8E  A 502 (-4.8A)
 1.20A 3d90B-3bryA:
undetectable		 3d90B-3bryA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 7 LEU A 165
LEU A 248
ILE A 202
PHE A 204
 None
None
C8E  A 502 (-4.0A)
None
 0.86A 3ln1B-3bryA:
undetectable		 3ln1B-3bryA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 3bry TBUX
(Ralstonia
pickettii) 		5 / 12 ASP A  51
GLY A 382
ALA A 397
PHE A 396
ALA A 427
 None
 1.11A 3sudB-3bryA:
undetectable		 3sudB-3bryA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 5 GLY A  20
THR A  19
GLY A 284
GLU A  32
 None
 1.09A 4v20A-3bryA:
undetectable		 4v20A-3bryA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 3bry TBUX
(Ralstonia
pickettii) 		5 / 9 PRO A  34
LEU A  39
GLY A  38
LEU A 225
THR A 226
 None
 1.21A 4x3mB-3bryA:
undetectable		 4x3mB-3bryA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 6 HIS A 357
GLY A   8
GLU A   7
ARG A  14
 None
 1.28A 4zbqA-3bryA:
undetectable		 4zbqA-3bryA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODC_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 3bry TBUX
(Ralstonia
pickettii) 		4 / 4 GLN A 240
GLN A 280
PRO A  34
ALA A 238
 None
 1.39A 5odcA-3bryA:
undetectable
5odcG-3bryA:
undetectable		 5odcA-3bryA:
20.66
5odcG-3bryA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW4_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		5 / 9 THR A 381
GLY A 382
ALA A 397
GLY A 354
GLU A 343
 None
 0.96A 5vw4A-3bryA:
undetectable		 5vw4A-3bryA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3bry TBUX
(Ralstonia
pickettii) 		5 / 8 THR A 381
GLY A 382
ALA A 397
GLY A 354
GLU A 343
 None
 0.95A 5vw9A-3bryA:
undetectable		 5vw9A-3bryA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 3bry TBUX
(Ralstonia
pickettii) 		5 / 12 LEU A  39
GLY A  38
HIS A 145
SER A  47
ARG A  90
 None
 1.29A 6bxlB-3bryA:
undetectable		 6bxlB-3bryA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 3bry TBUX
(Ralstonia
pickettii) 		5 / 12 GLY A 200
GLY A 199
VAL A 123
ASN A 121
GLY A 196
 None
 1.15A 6gneA-3bryA:
undetectable		 6gneA-3bryA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 3bry TBUX
(Ralstonia
pickettii) 		5 / 12 GLY A 200
GLY A 199
VAL A 123
ASN A 121
GLY A 196
 None
 1.15A 6gneB-3bryA:
undetectable		 6gneB-3bryA:
21.85