SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bs5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3bs5 CONNECTOR ENHANCER
OF KINASE SUPPRESSOR
OF RAS 2
(Homo
sapiens) 		5 / 9 LEU B 132
LEU B 157
GLU B 169
ILE B 152
VAL B 121
 None
 1.41A 1gx8A-3bs5B:
undetectable		 1gx8A-3bs5B:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 3bs5 CONNECTOR ENHANCER
OF KINASE SUPPRESSOR
OF RAS 2
PROTEIN AVEUGLE
(Drosophila
melanogaster;
Homo
sapiens) 		3 / 3 LEU B 160
PHE B 139
ARG A  61
 None
 0.79A 1xdkB-3bs5B:
undetectable		 1xdkB-3bs5B:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 3bs5 PROTEIN AVEUGLE
(Drosophila
melanogaster) 		3 / 3 ALA A  22
VAL A  23
GLN A  88
 None
 0.65A 3of4B-3bs5A:
undetectable		 3of4B-3bs5A:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_ACTA608_0
(SERUM ALBUMIN)		 3bs5 PROTEIN AVEUGLE
(Drosophila
melanogaster) 		3 / 3 LYS A  33
ARG A  37
HIS A  38
 None
 1.10A 4zbrA-3bs5A:
2.3		 4zbrA-3bs5A:
9.78