SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bs6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3bs6 INNER MEMBRANE
PROTEIN OXAA
(Escherichia
coli) 		6 / 12 THR A 237
ASP A 236
ALA A 239
GLY A 220
LEU A 256
TYR A 233
 None
 1.32A 1rjdA-3bs6A:
undetectable		 1rjdA-3bs6A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 3bs6 INNER MEMBRANE
PROTEIN OXAA
(Escherichia
coli) 		6 / 12 THR A 237
ASP A 236
ALA A 239
GLY A 220
LEU A 256
TYR A 233
 None
 1.34A 1rjdC-3bs6A:
undetectable		 1rjdC-3bs6A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 3bs6 INNER MEMBRANE
PROTEIN OXAA
(Escherichia
coli) 		4 / 5 VAL A 253
GLN A 198
PHE A 193
ARG A 219
 None
None
PG4  A 336 (-3.9A)
None
 1.30A 3bjwH-3bs6A:
undetectable		 3bjwH-3bs6A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 3bs6 INNER MEMBRANE
PROTEIN OXAA
(Escherichia
coli) 		4 / 5 VAL A 253
GLN A 198
PHE A 193
ARG A 219
 None
None
PG4  A 336 (-3.9A)
None
 1.25A 3bjwB-3bs6A:
undetectable		 3bjwB-3bs6A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)		 3bs6 INNER MEMBRANE
PROTEIN OXAA
(Escherichia
coli) 		3 / 3 MET A 255
GLN A 258
TYR A 259
 None
 0.97A 4udcA-3bs6A:
undetectable		 4udcA-3bs6A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 3bs6 INNER MEMBRANE
PROTEIN OXAA
(Escherichia
coli) 		4 / 7 PHE A 165
ILE A  72
GLY A  77
LYS A 163
 None
 1.03A 4zxiA-3bs6A:
undetectable		 4zxiA-3bs6A:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 3bs6 INNER MEMBRANE
PROTEIN OXAA
(Escherichia
coli) 		3 / 3 THR A 306
HIS A 267
ASN A 304
 None
None
PGE  A 338 (-3.4A)
 0.91A 5n4tA-3bs6A:
undetectable		 5n4tA-3bs6A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0C_D_TA1D502_1
(TUBULIN BETA CHAIN)		 3bs6 INNER MEMBRANE
PROTEIN OXAA
(Escherichia
coli) 		5 / 12 LEU A 167
SER A 305
LEU A  70
THR A  71
GLY A  76
 None
 0.99A 6b0cD-3bs6A:
undetectable		 6b0cD-3bs6A:
14.45