SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bsx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_A_NIOA145_1
(LEGHEMOGLOBIN A)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
4 / 8 PHE A 905
ILE A 885
LEU A 870
VAL A 881
None
0.86A 1fslA-3bsxA:
undetectable
1fslA-3bsxA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
4 / 8 PHE A 905
ILE A 885
LEU A 870
VAL A 881
None
0.81A 1fslB-3bsxA:
undetectable
1fslB-3bsxA:
17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RBP_A_RTLA183_0
(PLASMA
RETINOL-BINDING
PROTEIN PRECURSOR)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
5 / 12 LEU A 986
LEU A 957
ALA A 929
VAL A 954
LEU A 942
None
0.88A 1rbpA-3bsxA:
undetectable
1rbpA-3bsxA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
5 / 10 LEU A1036
LEU A1029
ILE A1046
GLU A 979
LEU A1014
None
1.12A 1wopA-3bsxA:
undetectable
1wopA-3bsxA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
4 / 9 ILE A1061
ALA A1078
VAL A1081
CYH A1085
None
1.06A 2vufB-3bsxA:
undetectable
2vufB-3bsxA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
4 / 6 VAL A1082
LEU A1097
GLU A1100
SER A1073
None
1.21A 3b6rB-3bsxA:
undetectable
3b6rB-3bsxA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
3 / 3 LYS A1060
ARG A1054
LYS A 994
None
1.49A 3okxA-3bsxA:
undetectable
3okxA-3bsxA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_1
(NS3 PROTEASE, NS4A
PROTEIN)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
5 / 12 GLN A 931
VAL A 937
GLY A 934
ALA A 889
ALA A 888
None
0.96A 3sufB-3bsxA:
undetectable
3sufB-3bsxA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_D_VIVD301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
5 / 12 LEU A1026
VAL A1049
LEU A1050
ILE A1065
LEU A1072
None
1.09A 3w67D-3bsxA:
undetectable
3w67D-3bsxA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_C_ADNC501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
3 / 3 PRO A1055
VAL A1049
HIS A1048
None
0.75A 4pevC-3bsxA:
undetectable
4pevC-3bsxA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQY_A_BEZA401_0
(THIOREDOXIN)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
4 / 8 ILE A 866
PHE A 856
GLN A 858
GLU A 855
None
1.02A 5dqyA-3bsxA:
undetectable
5dqyA-3bsxA:
21.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5KLA_A_ACTA1505_0
(MATERNAL PROTEIN
PUMILIO)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
3 / 3 HIS A1075
LYS A1076
PHE A1077
None
G  C   3 ( 3.7A)
U  C   4 ( 4.4A)
0.58A 5klaA-3bsxA:
41.6
5klaA-3bsxA:
78.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
5 / 12 GLY A 970
VAL A1009
ILE A 921
GLY A 934
ALA A 941
None
0.99A 6c2mD-3bsxA:
undetectable
6c2mD-3bsxA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QYA_B_FOZB401_0
(THYMIDYLATE SYNTHASE)
3bsx PUMILIO HOMOLOG 1
(Homo
sapiens)
5 / 12 LEU A 892
ILE A 902
LEU A 928
GLY A 934
ILE A 921
None
1.11A 6qyaB-3bsxA:
undetectable
6qyaB-3bsxA:
23.87