SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bt3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		5 / 10 THR A 252
GLY A 255
CYH A 256
PHE A 158
THR A 148
 None
 1.08A 1h4oA-3bt3A:
undetectable
1h4oB-3bt3A:
undetectable		 1h4oA-3bt3A:
21.51
1h4oB-3bt3A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		5 / 8 THR A 252
GLY A 255
CYH A 256
PHE A 158
THR A 148
 None
 1.11A 1h4oB-3bt3A:
undetectable		 1h4oB-3bt3A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		5 / 9 THR A 252
GLY A 255
CYH A 256
PHE A 158
THR A 148
 None
 1.14A 1h4oC-3bt3A:
undetectable
1h4oD-3bt3A:
undetectable		 1h4oC-3bt3A:
21.51
1h4oD-3bt3A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		5 / 9 THR A 252
GLY A 255
CYH A 256
PHE A 158
THR A 148
 None
 1.16A 1h4oD-3bt3A:
undetectable		 1h4oD-3bt3A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		5 / 9 THR A 252
GLY A 255
CYH A 256
PHE A 158
THR A 148
 None
 1.16A 1h4oE-3bt3A:
undetectable
1h4oF-3bt3A:
undetectable		 1h4oE-3bt3A:
21.51
1h4oF-3bt3A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		5 / 9 THR A 252
GLY A 255
CYH A 256
PHE A 158
THR A 148
 None
 1.14A 1h4oF-3bt3A:
undetectable		 1h4oF-3bt3A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		5 / 9 THR A 252
GLY A 255
CYH A 256
PHE A 158
THR A 148
 None
 1.09A 1h4oH-3bt3A:
undetectable		 1h4oH-3bt3A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		5 / 9 THR A 252
GLY A 255
CYH A 256
PHE A 158
THR A 148
 None
 1.14A 1hd2A-3bt3A:
undetectable		 1hd2A-3bt3A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		5 / 8 THR A 252
GLY A 255
CYH A 256
PHE A 158
THR A 148
 None
 1.11A 1oc3A-3bt3A:
undetectable		 1oc3A-3bt3A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		5 / 9 THR A 252
GLY A 255
CYH A 256
PHE A 158
THR A 148
 None
 1.16A 1oc3B-3bt3A:
undetectable		 1oc3B-3bt3A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		5 / 10 THR A 252
GLY A 255
CYH A 256
PHE A 158
THR A 148
 None
 1.16A 2vl2A-3bt3A:
undetectable
2vl2C-3bt3A:
undetectable		 2vl2A-3bt3A:
21.28
2vl2C-3bt3A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		4 / 7 GLY A 177
ASP A 178
GLY A 175
GLU A 174
 None
 0.89A 4koeA-3bt3A:
undetectable
4koeB-3bt3A:
undetectable
4koeD-3bt3A:
undetectable		 4koeA-3bt3A:
15.30
4koeB-3bt3A:
15.30
4koeD-3bt3A:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		5 / 9 VAL A 169
ALA A 170
TYR A 179
GLY A 166
GLY A 177
 None
 1.39A 4mmfA-3bt3A:
undetectable		 4mmfA-3bt3A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		4 / 7 GLY A 177
ASP A 178
GLY A 175
GLU A 174
 None
 0.86A 4z53A-3bt3A:
undetectable
4z53B-3bt3A:
undetectable		 4z53A-3bt3A:
10.97
4z53B-3bt3A:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 PHE A 260
ILE A 250
ASP A 237
 None
 0.61A 5cswA-3bt3A:
undetectable		 5cswA-3bt3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		3 / 3 PHE A 260
ILE A 250
ASP A 237
 None
 0.65A 5cswB-3bt3A:
undetectable		 5cswB-3bt3A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 3bt3 GLYOXALASE-RELATED
ENZYME, ARAC TYPE
(Lachnoclostridiu
m
phytofermentans) 		4 / 8 LEU A 258
VAL A 227
LEU A 162
ILE A 161
 None
 0.88A 6cb4A-3bt3A:
undetectable		 6cb4A-3bt3A:
14.99