SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3bt5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
3 / 3 GLN A  46
HIS A 134
ARG A 133
None
1.04A 1zlqA-3bt5A:
undetectable
1zlqA-3bt5A:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
4 / 8 LEU A  68
LEU A  72
ALA A  51
LEU A  48
None
0.80A 2vcvP-3bt5A:
undetectable
2vcvP-3bt5A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
3 / 3 HIS A 134
HIS A 135
MET A 131
None
0.74A 3mihA-3bt5A:
undetectable
3mihA-3bt5A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB502_1
(HEMOLYTIC LECTIN
CEL-III)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
4 / 6 GLU A 168
GLY A 167
LEU A  66
GLU A 173
None
1.09A 3w9tB-3bt5A:
undetectable
3w9tB-3bt5A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE502_1
(HEMOLYTIC LECTIN
CEL-III)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
4 / 6 GLU A 168
GLY A 167
LEU A  66
GLU A 173
None
1.10A 3w9tE-3bt5A:
undetectable
3w9tE-3bt5A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF503_1
(HEMOLYTIC LECTIN
CEL-III)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
4 / 6 GLU A 168
GLY A 167
LEU A  66
GLU A 173
None
1.10A 3w9tF-3bt5A:
undetectable
3w9tF-3bt5A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
4 / 5 HIS A  44
ALA A  47
HIS A 134
GLN A 165
None
1.44A 4gboA-3bt5A:
undetectable
4gboA-3bt5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
4 / 5 HIS A  44
ALA A  47
HIS A 134
GLN A 165
None
1.44A 4gboB-3bt5A:
undetectable
4gboB-3bt5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
4 / 8 GLU A  56
GLN A  71
ILE A  70
LEU A  50
None
0.89A 4mj8A-3bt5A:
undetectable
4mj8A-3bt5A:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2D_F_LFXF102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
3 / 4 ARG A 170
GLY A 174
GLU A 173
None
0.64A 4z2dB-3bt5A:
undetectable
4z2dC-3bt5A:
undetectable
4z2dB-3bt5A:
15.06
4z2dC-3bt5A:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
3 / 3 MET A  81
GLN A  80
ARG A  79
None
None
CL  A 200 (-4.4A)
1.00A 5ewzB-3bt5A:
5.0
5ewzB-3bt5A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M35_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
3 / 3 MET A  81
GLN A  80
ARG A  79
None
None
CL  A 200 (-4.4A)
0.99A 5m35B-3bt5A:
undetectable
5m35B-3bt5A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M36_A_BEZA303_0
(14-3-3 PROTEIN
ZETA/DELTA)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
3 / 3 MET A  81
GLN A  80
ARG A  79
None
None
CL  A 200 (-4.4A)
1.02A 5m36A-3bt5A:
3.4
5m36A-3bt5A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_A_CUA301_0
(AA10A)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
4 / 5 HIS A  44
ALA A  47
HIS A 134
GLN A 165
None
1.47A 5uizA-3bt5A:
undetectable
5uizA-3bt5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FN9_A_BEZA302_0
(14-3-3 PROTEIN
ZETA/DELTA)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
3 / 3 MET A  81
GLN A  80
ARG A  79
None
None
CL  A 200 (-4.4A)
1.01A 6fn9A-3bt5A:
5.3
6fn9A-3bt5A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNA_B_BEZB302_0
(14-3-3 PROTEIN
ZETA/DELTA)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
3 / 3 MET A  81
GLN A  80
ARG A  79
None
None
CL  A 200 (-4.4A)
0.99A 6fnaB-3bt5A:
2.9
6fnaB-3bt5A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FNB_A_BEZA301_0
(14-3-3 PROTEIN
ZETA/DELTA)
3bt5 UNCHARACTERIZED
PROTEIN DUF305

(Deinococcus
radiodurans)
3 / 3 MET A  81
GLN A  80
ARG A  79
None
None
CL  A 200 (-4.4A)
1.01A 6fnbA-3bt5A:
2.8
6fnbA-3bt5A:
19.31